Chapter 1. Perinatal healthcare system
01.1. Perinatal healthcare system and its regionalization
01.2. Maternal and neonatal transport
01.3. Maternal and Child Health Handbook and medical check-ups for pregnant women
01.4. Health insurance system
01.5. Cost for NICU stay
01.6. Limit of viability and ethical issues

Chapter 2. Physiology of extremely preterm infants
02.1. Terminology
02.2. Organ physiology of extremely preterm infants
02.3. Definition of live birth and limit of viability

Chapter 3. Resuscitation
03.1. Prenatal counseling
03.2. Delivery room management
03.3. Placental transfusion
03.4. Target SpO2 and oxygen concentration

Chapter 4. Respiratory care
04.1. Diagnosis
04.2. Monitoring and evaluation
04.3. Surfactant installation
04.4. Mechanical ventilation
04.5. High-frequency oscillatory ventilation (HFOV) management
04.6. Noninvasive respiratory support
04.7. Persistent pulmonary hypertension of the newborn (PPHN) management

Chapter 5. Respiratory care for chronic lung disease
05.1. Diagnosis and classification
05.2. Prevention of CLD
05.3. Glucocorticoid use
05.4. General support

Chapter 6. Circulatory support
06.1. General support
06.2. Echocardiography
06.3. Monitoring and evaluation (blood pressure, perfusion)
06.4. Volume expander
06.5. Pharmacological support
06.6. Management of anemia

Chapter 7. Patent ductus arteriosus
07.1. Diagnosis
07.2. Prophylaxis
07.3. Pharmacological treatment
07.4. Surgical intervention
07.5. Device closure

Chapter 8. Neurological diseases
08.1. Neuroimagings: Cranial ultrasound and brain MRI
08.2. Intraventricular hemorrhage and posthemorrhagic hydrocephalus
08.3. Periventricular leukomalacia

Chapter 9. Fluid management
09.1. General management
09.2. Thermal and humidity support and fluid balance
09.3. Electrolyte and mineral control during fluid therapy
09.4. Hemodialysis

Chapter 10. Nutritional support
10.1. Nutrition, growth, and requirements
10.2. Venous nutrition
10.3. Enteral feeding and use of breast milk
10.4. Probiotics
10.5. Diagnosis and management of necrotizing enterocolitis
10.6. Diagnosis and management of meconium-related ileus

Chapter 11. Infection control
11.1. Diagnosis and general management
11.2. Bacterial infection and fungal infection
11.3. Viral infection and others

Chapter 12. Working environment
12.1. Characteristics of perinatal medical center in Japan
12.2. Day-to-day management responsibilities
12.3. Overtime work of neonatal physicians

Chapter 13. Nursing care
13.1. Minimal handling
13.2. Skincare
13.3. Glycerin enemas
13.4. Positioning
13.5. Pain management
13.6. Family involvement

Chapter 14. Follow-up
14.1. System
14.2. Current outcomes from the NRNJ database [2003–17]

Appendix 1: Birth weight reference
Appendix 2: Postnatal growth
Appendix 3: Clinical data references by gestational age
Appendix 4: Drug Doses

Index