Handbook of Genetic Diagnostic Technologies in Reproductive Medicine-2판

1. The Brave New World of Genomics
2. Genetics at the Cell Level: The Human Cell Atlas
3. The Genetic Risk of a Couple Aiming to Conceive
4. Carrier Screening for Single-Gene Disorders
5. Meiotic Abnormalities in Infertile Males
6. Chromosomal Analysis of Sperm
7. Epigenetics in Sperm, Epigenetic Diagnostics, and Transgenerational Inheritance
8. Aneuploidy in Human Oocytes and Preimplantation Embryos
9. Epigenetics from Oocytes to Embryos
10. Embryo Kinetics and Aneuploidy
11. Preimplantation Genetic Testing of Aneuploidies (PGT-A)
12. Preimplantation Genetic Testing for Structural Rearrangements
13. Mosaicism in Preimplantation Embryos
14. Embryo Cell-Free DNA in the Culture Medium and Its Potential for Non-Invasive
15. Mitochondria and Embryo Viability
16. Preimplantation Genetic Diagnosis for Single Gene Disorders
17. Preimplantation Genetic Testing for Polygenic Disorders
18. Should Genome Editing Replace Embryo Selection Following PGT?
19. Molecular Diagnosis of Endometrial Receptivity
20. The Vaginal Microbiome
21. The Uterine Microbiota
22. Endometritis: New Times, New Opportunities
23. Decidualization Resistance: A New Condition Identified in Severe Preeclampsia
24. Advanced Cell Therapy for Asherman’s Syndrome
25. Differential Genetic Diagnosis between Leiomyoma and Leiomyosarcoma
26. Non-Invasive Prenatal Testing (NIPT)
27. Advances in Non-Invasive Diagnosis of Single-Gene Disorders and Fetal Exome
28. Chromosome Abnormalities in Human Pregnancy Loss: A Review of Cytogenetic and Molecular Analyses
29. Products of Conception: Current Methodologies and Clinical Applications
30. Mother and Embryo Cross Communication during Conception
31. Perinatal and Pediatric Outcome of Pregnancies Following PGT-M/SR/A
32. Genetic Counseling in Assisted Reproductive Technology

Index


Different genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to the clinic, aiming to improve outcomes in the clinic and result in a healthy baby in the home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus.

This expanded new edition covers the range of the latest genetic diagnostic technologies being translated into practice internationally to improve routine IVF procedures for the benefit of patients. Bringing together international experts to discuss their work, this text gives a context for the developments in this very fast-moving area of research and offers a comprehensive and rounded appraisal of hot topics.