Table of Contents
Chapter 1: The Human Immune Response
Chapter 2: Organization of the Immune System
Chapter 3: Innate Immunity
Chapter 4: Antigen Receptor Genes, Gene Products, and Coreceptors
Chapter 5: The Major Histocompatibility Complex
Chapter 6: Overview of T-Cell Recognition: Making Pathogens Visible to the Immune System
Chapter 7: B-Cell Development and Differentiation
Chapter 8: T-Cell Development
Chapter 9: Cytokines and Cytokine Receptors
Chapter 10: Chemokines and Chemokine Receptors
Chapter 11: Lymphocyte Adhesion and Trafficking
Chapter 12: T-Cell Activation and Tolerance
Chapter 13: Regulated Necrosis and Its Immunogenicity
Chapter 14: The Microbiota in Immunity and Inflammation
Chapter 15: Immunoglobulin Function
Chapter 16: Helper T-Cell Subsets and Control of the Inflammatory Response
Chapter 17: Cytotoxic T Lymphocytes and Natural Killer Cells
Chapter 18: Regulatory Immune Cells
Chapter 19: Host Defenses in Skin
Chapter 20: Host Defenses at Mucosal Surfaces
Chapter 21: The Human Complement System: Basic Concepts and Clinical Relevance
Chapter 22: Phagocyte Deficiencies
Chapter 23: Mast Cells, Basophils, and Mastocytosis
Chapter 24: Eosinophils and Eosinophilia
Chapter 25: Host Defenses to Viruses
Chapter 26: Host Defenses to Intracellular Bacteria
Chapter 27: Host Defenses to Extracellular Bacteria
Chapter 28: Host Defenses to Spirochetes
Chapter 29: Host Defenses to Fungal Pathogens
Chapter 30: Host Defenses to Protozoa
Chapter 31: Immune Responses to Helminth Infection
Chapter 32: Approach to the Evaluation of the Patient with Suspected Immunodeficiency
Chapter 33: Human Genomics in Immunology
Chapter 34: Primary Antibody Deficiencies
Chapter 35: Primary T-Cell Immunodeficiencies
Chapter 36: Immunodeficiencies at the Interface of Innate and Adaptive Immunity
Chapter 37: Infections in the Immunocompromised Host
Chapter 38: Immune Deficiencies at the Extremes of Age
Chapter 39: Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome
Chapter 40: Autoantibody-Mediated Phenocopies of Primary Immunodeficiency Diseases
Chapter 41: Immunological Mechanisms of Airway Diseases and Pathways to Therapy
Chapter 42: Urticaria, Angioedema, and Anaphylaxis
Chapter 43: Allergic Reactions to Stinging and Biting Insects
Chapter 44: Atopic and Contact Dermatitis
Chapter 45: Food Allergy
Chapter 46: Eosinophil-Associated Gastrointestinal Disorders
Chapter 47: Allergic Disorders of the Eye
Chapter 48: Drug Hypersensitivity
Chapter 49: Occupational Respiratory Allergies
Chapter 50: Mechanisms of Autoimmunity
Chapter 51: Systemic Lupus Erythematosus
Chapter 52: Rheumatoid Arthritis
Chapter 53: Juvenile Idiopathic Arthritis
Chapter 54: Sj?ren Syndrome
Chapter 55: Scleroderma뻊ystemic Sclerosis
Chapter 56: Inflammatory Muscle Diseases
Chapter 57: Spondyloarthritis
Chapter 58: Small- and Medium-Vessel Primary Vasculitis
Chapter 59: Large-Vessel Vasculitides
Chapter 60: Systemic Autoinflammatory Syndromes
Chapter 61: Antiphospholipid Syndrome
Chapter 62: Immunohematological Disorders
Chapter 63: Bullous Diseases of the Skin and Mucous Membranes
Chapter 64: Immunology of Psoriasis
Chapter 65: Myasthenia Gravis
Chapter 66: Multiple Sclerosis
Chapter 67: Autoimmune Peripheral Neuropathies
Chapter 68: Immunological Renal Diseases
Chapter 69: Inflammation and Atherothrombosis
Chapter 70: Autoimmune Thyroid Diseases
Chapter 71: Type 1 Diabetes
Chapter 72: Immunological Lung Diseases
Chapter 73: Sarcoidosis
Chapter 74: Immunological Ocular Disease
Chapter 75: Immunological Diseases of the Gastrointestinal Tract
Chapter 76: Inflammatory Hepatobiliary Diseases
Chapter 77: Immunotherapy of Cancer
Chapter 78: Lymphoid Leukemias
Chapter 79: Lymphomas
Chapter 80: Monoclonal Gammopathies
Chapter 81: Concepts and Challenges in Organ Transplantation: Rejection, Immunosuppression, and Tolerance
Chapter 82: Immune Reconstitution Therapy for Immunodeficiency
Chapter 83: Hematopoietic Stem Cell Transplantation for Malignant Diseases
Chapter 84: Immunoglobulin Therapy: Replacement and Immunomodulation
Chapter 85: Gene Therapy for Primary Immune Deficiency Diseases
Chapter 86: Glucocorticoids
Chapter 87: Immunomodulating Pharmaceuticals
Chapter 88: Protein Kinase Antagonists in Therapy of Immunological and Inflammatory Diseases
Chapter 89: Biological Modifiers of Inflammatory Diseases
Chapter 90: Vaccines
Chapter 91: Immunotherapy of Allergic Disease
Chapter 92: Flow Cytometry
Chapter 93: Assessment of Functional Immune Responses in Lymphocytes
Chapter 94: Assessment of Neutrophil Function
Chapter 95: Assessment of Human Allergic Diseases
Chapter 96: Molecular Methods