Cover image
Title Page
Table of Contents
Award page
Copyright
Dedication
Contributors
Preface
Acknowledgments
Get the most out of The Developing Human 11th Edition!
1. Introduction to Human Development
Developmental Periods
Significance of Embryology
Historical Gleanings
Genetics and Human Development
Molecular Biology of Human Development
Descriptive Terms in Embryology
Clinically Oriented Problems
Bibliography and Suggested Reading
2. First Week of Human Development
Gametogenesis
Meiosis
Spermatogenesis
Oogenesis
Comparison of Gametes
Uterus, Uterine Tubes, and Ovaries
Female Reproductive Cycles
Ovarian Cycle
Menstrual Cycle
Transportation of Gametes
Maturation of Sperms
Viability of Gametes
Sequence of Fertilization
Cleavage of Zygote
Formation of Blastocyst
Summary of First Week
Clinically Oriented Problems
Bibliography and Suggested Reading
3. Second Week of Human Development
Completion of Implantation of Blastocyst
Formation of Amniotic Cavity, Embryonic Disc, and Umbilical Vesicle
Development of Chorionic Sac
Implantation Sites of Blastocysts
Summary of Implantation
Summary of Second Week
Clinically Oriented Problems
Bibliography and Suggested Reading
4. Third Week of Human Development
Gastrulation: Formation of Germ Layers
Primitive Streak
Notochordal Process and Notochord
Allantois
Neurulation: Formation of Neural Tube
Development of Somites
Development of Intraembryonic Coelom
Early Development of Cardiovascular System
Development of Chorionic Villi
Summary of Third Week
Clinically Oriented Problems
Bibliography and Suggested Reading
5. Fourth to Eighth Weeks of Human Development
Phases of Embryonic Development
Folding of Embryo
Germ Layer Derivatives
Control of Embryonic Development
Highlights of Fourth to Eighth Weeks
Estimation of Embryonic Age
Summary of Fourth to Eighth Weeks
Clinically Oriented Problems
Bibliography and Suggested Reading
6. Fetal Period
Estimation of Fetal Age
Highlights of Fetal Period
Expected Date of Delivery
Factors Influencing Fetal Growth
Procedures for Assessing Fetal Status
Summary of Fetal Period
Clinically Oriented Problems
Bibliography and Suggested Reading
7. Placenta and Fetal Membranes
Placenta
Parturition
Umbilical Vesicle
Allantois
Multiple Pregnancies
Summary of Placenta and Fetal Membranes
Neonatal Period
Clinically Oriented Problems
Bibliography and Suggested Reading
8. Body Cavities, Mesenteries, and Diaphragm
Embryonic Body Cavity
Development of Diaphragm
Summary of Development of Body Cavities, Mesenteries, and Diaphragm
Clinically Oriented Problems
Bibliography and Suggested Reading
9. Pharyngeal Apparatus, Face, and Neck
Pharyngeal Arches
Pharyngeal Pouches
Pharyngeal Grooves
Pharyngeal Membranes
Development of Thyroid Gland
Development of Tongue
Development of Salivary Glands
Development of Face
Development of Nasal Cavities
Development of Palate
Summary of Pharyngeal Apparatus, Face, and Neck
Clinically Oriented Problems
Bibliography and Suggested Reading
10. Respiratory System
Respiratory Primordium
Development of Larynx
Development of Trachea
Development of Bronchi and Lungs
Summary of Respiratory System
Clinically Oriented Problems
Bibliography and Suggested Reading
11. Alimentary System
Foregut
Midgut
Hindgut
Enteric Nervous System
Summary of Alimentary System
Clinically Oriented Problems
Bibliography and Suggested Reading
12. Urogenital System
Development of Urinary System
Development of Suprarenal Glands
Development of Genital System
Development of External Genitalia
Development of Inguinal Canals
Relocation of Testes and Ovaries
Summary of Urogenital System
Clinically Oriented Problems
Bibliography and Suggested Reading
13. Cardiovascular System
Early Development of Heart and Blood Vessels
Later Development of Heart
Birth Defects of Heart and Great Vessels
Derivatives of Pharyngeal Arch Arteries
Fetal and Neonatal Circulation
Development of Lymphatic System
Summary of Cardiovascular System
Clinically Oriented Problems
Bibliography and Suggested Reading
14. Skeletal System
Development of Bone and Cartilage
Development of Joints
Development of Axial Skeleton
Development of Appendicular Skeleton
Summary of Skeletal System
Clinically Oriented Problems
Bibliography and Suggested Reading
15. Muscular System
Development of Skeletal Muscle
Development of Smooth Muscle
Development of Cardiac Muscle
Summary of Muscular System
Clinically Oriented Problems
Bibliography and Suggested Reading
16. Development of Limbs
Early Stages of Limb Development
Final Stages of Limb Development
Birth Defects of Limbs
Summary of Limb Development
Clinically Oriented Problems
Bibliography and Suggested Reading
17. Nervous System
Development of Nervous System
Development of Spinal Cord
Development of Brain
Birth Defects of Brain
Development of Peripheral Nervous System
Development of Autonomic Nervous System
Summary of Nervous System
Clinically Oriented Problems
Bibliography and Suggested Reading
18. Development of Eyes and Ears
Development of Eyes and Related Structures
Development of Ears
Summary of Eye Development
Summary of Ear Development
Clinically Oriented Problems
Bibliography and Suggested Reading
19. Integumentary System
Development of Skin and Appendages
Summary of Integumentary System
Clinically Oriented Problems
Bibliography and Suggested Reading
20. Human Birth Defects
Classification of Birth Defects
Teratology: Study of Abnormal Development
Birth Defects Caused by Genetic Factors
Birth Defects Caused by Environmental Factors
Birth Defects Caused by Multifactorial Inheritance
Summary of Birth Defects
Clinically Oriented Problems
Bibliography and Suggested Reading
21. Common Signaling Pathways Used During Development
Intercellular Communication
Morphogens
Protein Kinases
NOTCH-DELTA Pathway
Transcription Factors
Epigenetics
Stem Cells: Differentiation Versus Pluripotency
Summary of Common Signaling Pathways Used During Development
Bibliography and Suggested Reading
Appendix Discussion of Clinically Oriented Problems
Chapter 1
Chapter 2
Chapter 3
Chapter 4
Chapter 5
Chapter 6
Chapter 7
Chapter 8
Chapter 9
Chapter 10
Chapter 11
Chapter 12
Chapter 13
Chapter 14
Chapter 15
Chapter 16
Chapter 17
Chapter 18
Chapter 19
Chapter 20
Index