Bone Marrow Pathology-5판

Comprehensively updated with new information on bone marrow pathology – incorporating new advances in the diagnosis,
classification and understanding of haematological disorders

This fifth edition has been extensively revised and expanded to reflect the significant advances that have occurred in the
application of cytogenetics and, in particular, molecular genetics in the diagnosis, classification and understanding of
haematological disorders. It not only provides information on all common disease entities but also covers rare disorders in
which bone marrow examination is useful. Designed as a practical resource for clinical use, it features 'Problems and Pitfalls'
sections throughout to aid diagnosis.

Bone Marrow Pathology, 5th Edition is comprised of chapters covering: normal bone marrow; special techniques applicable to
bone marrow diagnosis; infection and reactive changes; acute myeloid leukaemia, mixed phenotype acute leukaemia,
myelodysplastic syndromes and histiocytic neoplasms; myeloproliferative and myelodysplastic/myeloproliferative neoplasms and
related conditions; lymphoproliferative disorders; plasma cell neoplasms; disorders of erythropoiesis, granulopoiesis and
thrombopoiesis; miscellaneous disorders; metastatic and non-haemopoietic tumours; and diseases of bone.

Offers specific information for clinicians working in low- and middle-income countries

Practical and highly applicable, Bone Marrow Pathology, 5th Edition is an essential resource for haematologists,
haemato- oncologists, haematopathologists and pathologists, plus trainees and laboratory scientists in these disciplines.

ABOUT THE AUTHOR
Barbara J. Bain, MBBS, FRACP, FRCPath, is Professor of Diagnostic Haematology, St Mary's Hospital Campus, Imperial College Faculty of Medicine, and Honorary Consultant Haematologist, St Mary's Hospital, London, UK.

David M. Clark MD, MRCP (UK), FRCPath, is Consultant Haematopathologist, Nottingham University Hospitals NHS Trust, Nottingham and Honorary Clinical Senior Lecturer, Imperial College London.

Bridget S. Wilkins DM, PhD, FRCPath, is Consultant Haematopathologist, Guy's and St Thomas' Hospitals NHS Foundation Trust, London and Hampshire Hospitals NHS Foundation Trust, Winchester, and Honorary Clinical Senior Lecturer, Imperial College London.




01 The normal bone marrow, 1

02 Special techniques applicable to bone marrow diagnosis, 61

03 Infection and reactive changes, 109

04 Acute myeloid leukaemia, mixed phenotype acute leukaemia,the myelodysplastic syndromes and histiocytic neoplasms, 185

05 Myeloproliferative and myelodysplastic/myeloproliferative neoplasms and related conditions, 267

06 Lymphoproliferative disorders, 346

07 Plasma cell neoplasms, 487

08 Disorders of erythropoiesis, granulopoiesis and thrombopoiesis, 537

09 Miscellaneous disorders, 585

10 Metastatic and non‐haemopoietic tumours, 645

11 Diseases of bone, 685

Appendix, 699

Index, 709