Fast Facts: Measurable Residual Disease: A clearer picture for treatment decisions

Conventional methods of detecting disease remission in cancers such as leukemia rely on microscopic analysis of tissue samples.
Measurable (or minimal) residual disease (MRD) describes the presence of disease beyond the levels of sensitivity afforded by
microscopy.
Fast Facts: Measurable Residual Disease describes what is meant by MRD, the opportunities and challenges afforded by its
identification and the advantages and disadvantages of the methods used for its detection.
Specific examples are given to illustrate the implications of detecting MRD in different disease scenarios, with emphasis on
acute myeloid and lymphoblastic leukemias.
With the recognition and monitoring of MRD likely to play an increasingly important role in disease prognosis and subsequent
treatment direction, this accessible resource is ideal for any healthcare professional wanting to know more about this exciting
and fast-moving area.

• What is measurable residual disease?
• How is MRD measured?
• What is the significance of MRD?