Fast Facts: Prostate Cancer: If when and how to intervene

Cover
Title Page
Copyright
Contents
List of abbreviations
Introduction
Epidemiology and pathophysiology
Global patterns
Risk factors
Histological features
Patterns of disease spread
Diet, lifestyle and chemoprevention
Effect on development
Effect on progression
Screening and early detection
Early detection
Screening
Clinical symptoms
Diagnosis, staging and prognostic indicators
Diagnosis
Staging
Prognostic indicators
Summary of diagnostic and staging options
Management of clinically localized disease
Active surveillance
Radical prostatectomy
Radiotherapy
Watchful waiting
Experimental techniques
Antiandrogen monotherapy
Management of local complications
Managing recurrence after initial therapy
Recurrence after prostatectomy
Recurrence following radiation therapy
Managing metastatic hormone-sensitive prostate cancer
Oligometastatic cancer and widespread metastases
Orchiectomy
LHRH analogs
LHRH antagonists
Antiandrogens
Maximal androgen blockade
The timing of hormonal therapy
Intermittent hormonal therapy
ADT in combination therapy
Local treatment of the primary tumor
Treatment of oligometastatic disease
Management of castrate-resistant prostate cancer
Further hormonal manipulation
Non-metastatic castrate-resistant prostate cancer
Metastatic castrate-resistant prostate cancer
Immunotherapy
PARP inhibitors
PSMA radioligand therapy
Management of bone metastases
Palliative care
Treatment algorithm
Survivorship and management of treatment-related side effects and complications
Survivorship
Sexual function
Urinary and bowel symptoms
Other side effects
Useful resources
Index