Fast Facts: Thrombotic Thrombocytopenic Purpura

Cover
Title Page
Copyright
Contents
List of abbreviations
Introduction
Disease overview
Epidemiology
Etiology
Clinical presentation
Classic presentation of acute TTP
Atypical presentations in adulthood
Childhood and adolescent onset
Association with other autoimmune diseases
Congenital (hereditary) TTP
End-organ damage in cTTP
Subacute features of cTTP
Presentation in pregnancy
Differential diagnosis
Immune-mediated TTP
STEC-HUS (typical or diarrhea-associated HUS)
Atypical HUS
Drug-induced TMA
Secondary TMA
Systemic causes of anemia and/or thrombocytopenia that mimic TMA
Differential diagnostic approach
Laboratory findings and diagnosis
Diagnosing TTP
Confirming the diagnosis
Screening for severe ADAMTS13 deficiency
Management
Immune-mediated TTP
Congenital TTP
Useful resources
Index