Cutaneous Soft Tissue Tumors

Cutaneous Soft Tissue Tumors
Cover
Title Page
Copyright Information
Dedication
Preface
Acknowledgments
Section 1: Fibrohistiocytic Tumors
Chapter 1: Classification of Fibrohistiocytic Tumors
Classification of Fibrohistiocytic Tumors
Table 1-1: Classification of Fibrohistiocytic Tumors of the Skin
References
Chapter 2: Dermatofibroma
Chapter 2 Introduction
Table 2-1: Clinicopathologic Variants of Dermatofibroma
Clinical Variants of Dermatofibroma
Figure 2-1
Figure 2-2
Figure 2-3
Figure 2-4
Figure 2-5
Figure 2-6
Figure 2-7
Figure 2-8
Histopathologic Characteristics
Figure 2-9
Figure 2-10
Figure 2-11
Figure 2-12
Figure 2-13
Figure 2-14
Figure 2-15
Figure 2-16
Figure 2-17
Figure 2-18
Figure 2-19
Figure 2-20
Figure 2-21
Figure 2-22
Figure 2-23
Figure 2-24
Figure 2-25
Figure 2-26
Treatment
References
Chapter 3: Juvenile Xanthogranuloma
Chapter 3 Introduction
Clinical Features
Figure 3-1
Figure 3-2
Figure 3-3
Figure 3-4
Histopathologic Characteristics
Figure 3-5
Figure 3-6
Figure 3-7
Figure 3-8
Figure 3-9
Treatment
References
Chapter 4: Solitary Reticulohistiocytoma and Multicentric Reticulohistiocytosis
Chapter 4 Introduction
Clinical Features
Figure 4-1
Figure 4-2
Histopathologic Characteristics
Figure 4-3
Figure 4-4
Treatment
References
Chapter 5: Acrochordons and Pendulous Fibromas
Chapter 5 Introduction
Clinical Features
Figure 5-1
Figure 5-2
Figure 5-3
Figure 5-4
Figure 5-5
Figure 5-6
Figure 5-7
Figure 5-8
Figure 5-9
Histopathologic Characteristics
Figure 5-10
Figure 5-11
Figure 5-12
Treatment
References
Chapter 6: Cutaneous Solitary Fibrous Tumor
Chapter 6 Introduction
Clinical Features
Figure 6-1
Histopathologic Characteristics
Figure 6-2
Figure 6-3
Figure 6-3
Figure 6-3
Figure 6-4
Treatment
References
Chapter 7: Sclerotic Fibroma (Storiform Collagenoma)
Chapter 7 Introduction
Clinical Features
Figure 7-1
Figure 7-2
Histopathologic Characteristics
Figure 7-3
Figure 7-4
Figure 7-5
Treatment
References
Chapter 8: Plaque-Like CD34-Positive Dermal Fibroma (Medallion-Like Dermal Dendrocyte Hamartoma)
Chapter 8 Introduction
Clinical Features
Figure 8-1
Histopathologic Characteristics
Figure 8-2
Figure 8-3
Figure 8-4
Treatment
References
Chapter 9: Desmoplastic Fibroblastoma (Collagenous Fibroma)
Chapter 9 Introduction
Clinical Features
Figure 9-1
Histopathologic Characteristics
Figure 9-2
Treatment
References
Chapter 10: Pleomorphic Fibroma of the Skin
Clinical Features
Figure 10-1
Histopathologic Characteristics
Figure 10-2
Treatment
References
Chapter 11: Fibroma of Tendon Sheath
Clinical Features
Figure 11-1
Figure 11-2
Histopathologic Characteristics
Figure 11-3
Treatment
References
Chapter 12: Giant Cell Tumor of Tendon Sheath
Chapter 12 Introduction
Clinical Features
Figure 12-1
Figure 12-2
Histopathologic Characteristics
Figure 12-3
Figure 12-4
Treatment
References
Chapter 13: Cutaneous Myxoma
Clinical Features
Figure 13-1
Figure 13-2
Histopathologic Characteristics
Figure 13-3
Figure 13-4
Treatment
References
Chapter 14: Superficial Acral Fibromyxoma
Clinical Features
Figure 14-1
Figure 14-2
Histopathologic Characteristics
Figure 14-3
Treatment
References
Chapter 15: Cellular Digital Fibroma
Clinical Features
Figure 15-1
Histopathologic Characteristics
Figure 15-2
Figure 15-3
Figure 15-4
Figure 15-5
Treatment
References
Chapter 16: Nuchal Fibroma and Gardner Syndrome–Associated Fibroma
Clinical Features
Figure 16-1
Histopathologic Characteristics
Figure 16-2
Treatment
References
Chapter 17: Cerebriform Collagenoma Associated with Proteus Syndrome
Chapter 17 Introduction
Clinical Features
Figure 17-1
Figure 17-2
Histopathologic Characteristics
Figure 17-3
Treatment
References
Chapter 18: Elastofibroma
Chapter 18 Introduction
Clinical Features
Figure 18-1
Histopathologic Characteristics
Figure 18-2
Treatment
References
Chapter 19: Nodular Fasciitis, Proliferative Fasciitis, and Ischemic Fasciitis
Chapter 19 Introduction
Clinical Features
Figure 19-1
Histopathologic Characteristics
Figure 19-2
Figure 19-3
Figure 19-4
Treatment
References
Chapter 20: Fibromatosis
Chapter 20 Introduction
Table 20-1: Classification of Fibromatoses
Clinical Features
Figure 20-1
Figure 20-2
Figure 20-3
Figure 20-4
Figure 20-5
Histopathologic Characteristics
Figure 20-6
Figure 20-7
Figure 20-8
Treatment
References
Chapter 21: Juvenile Hyaline Fibromatosis
Clinical Features
Figure 21-1
Histopathologic Characteristics
Figure 21-2
Treatment
References
Chapter 22: Fibrous Hamartoma of Infancy
Clinical Features
Figure 22-1
Histopathologic Characteristics
Figure 22-2
Figure 22-3
Treatment
References
Chapter 23: Calcifying Aponeurotic Fibroma
Chapter 23 Introduction
Clinical Features
Figure 23-1
Histopathologic Characteristics
Figure 23-2
Treatment
References
Chapter 24: Dermatofibrosarcoma Protuberans
Chapter 24 Introduction
Clinical Features
Figure 24-1
Figure 24-2
Figure 24-3
Figure 24-4
Histopathologic Characteristics
Figure 24-5
Figure 24-6
Figure 24-7
Figure 24-8
Figure 24-9
Figure 24-10
Figure 24-11
Figure 24-12
Figure 24-13
Figure 24-14
Figure 24-15
Figure 24-16
Treatment
References
Chapter 25: Angiomatoid Fibrous Histiocytoma
Chapter 25 Introduction
Clinical Features
Figure 25-1
Histopathologic Characteristics
Figure 25-2
Treatment
References
Chapter 26: Plexiform Fibrohistiocytic Tumor
Clinical Features
Figure 26-1
Histopathologic Characteristics
Figure 26-2
Figure 26-3
Treatment
References
Chapter 27: Soft Tissue Giant Cell Tumor of Low Malignant Potential
Chapter 27 Introduction
Clinical Features
Figure 27-1
Histopathologic Characteristics
Figure 27-2
Treatment
References
Chapter 28: Inflammatory Myofibroblastic Tumor
Chapter 28 Introduction
Clinical Features
Figure 28-1
Histopathologic Characteristics
Figure 28-2
Treatment
References
Chapter 29: Inflammatory Myxohyaline Tumor of Distal Extremities
Chapter 29 Introduction
Clinical Features
Figure 29-1
Histopathologic Characteristics
Figure 29-2
Treatment
References
Chapter 30: Atypical Fibroxanthoma
Chapter 30 Introduction
Clinical Features
Figure 30-1
Figure 30-2
Figure 30-3
Histopathologic Characteristics
Figure 30-4
Figure 30-5
Figure 30-6
Figure 30-7
Figure 30-8
Figure 30-9
Treatment
References
Chapter 31: Malignant Fibrous Histiocytoma
Chapter 31 Introduction
Clinical Features
Figure 31-1
Figure 31-2
Histopathologic Characteristics
Figure 31-3
Figure 31-4
Figure 31-5
Treatment
References
Chapter 32: Fibrosarcoma
Chapter 32 Introduction
Table 32-1: Classification of Fibrosarcomas
Clinical Features
Figure 32-1
Figure 32-2
Histopathologic Characteristics
Figure 32-3
Figure 32-4
Treatment
References
Chapter 33: Epithelioid Sarcoma
Clinical Features
Figure 33-1
Figure 33-2
Histopathologic Characteristics
Figure 33-3
Figure 33-4
Figure 33-5
Figure 33-5
Figure 33-5
Treatment
References
Chapter 34: Synovial Sarcoma
Chapter 34 Introduction
Clinical Features
Figure 34-1
Histopathologic Characteristics
Figure 34-2
Figure 34-3
Figure 34-4
Figure 34-5
Figure 34-5
Figure 34-5
Figure 34-6
Treatment
References
Chapter 35: Alveolar Soft Part Sarcoma
Clinical Features
Figure 35-1
Histopathologic Characteristics
Figure 35-2
Treatment
References
Section 2: Myofibroblastic and Muscle Tumors
Chapter 36: Myofibroblasts, Muscle Cells, and Classification of Skin Proliferations with Myofibroblastic
and Muscle Differentiation
Chapter 36 Introduction
Table 36-1: Classification of Cutaneous Proliferations with Myofibroblastic and Muscle Differentiation
The Myofibroblast
Table 36-2: Cutaneous Soft Tissue Tumors for Which a Myofibroblastic Differentiation Has Been Suggested
Figure 36-1
Smooth Muscle Cells
Figure 36-2
Figure 36-3
Figure 36-4
Striated Muscle Cells
Figure 36-5
Figure 36-6
References
Chapter 37: Infantile Myofibromatosis
Chapter 37 Introduction
Clinical Features
Table 37-1: Classification of Myofibromatoses
Figure 37-1
Histopathologic Characteristics
Figure 37-2
Figure 37-3
Treatment
References
Chapter 38: Infantile Digital Fibromatosis
Chapter 38 Introduction
Clinical Features
Figure 38-1
Figure 38-2
Histopathologic Characteristics
Figure 38-3
Treatment
References
Chapter 39: Cutaneous Myopericytoma (Adult Cutaneous Myofibroma)
Chapter 39 Introduction
Clinical Features
Figure 39-1
Histopathologic Characteristics
Figure 39-2
Figure 39-3
Figure 39-4
Figure 39-5
Figure 39-6
Figure 39-7
Treatment
References
Chapter 40: Cutaneous PEComa
Chapter 40 Introduction
Clinical Features
Figure 40-1
Histopathologic Characteristics
Figure 40-2
Figure 40-3
Figure 40-4
Treatment
References
Chapter 41: Dermatomyofibroma (Plaque-Like Dermal Fibromatosis)
Chapter 41 Introduction
Clinical Features
Figure 41-1
Histopathologic Characteristics
Figure 41-2
Treatment
References
Chapter 42: Genital Angiomyofibroblastoma
Chapter 42 Introduction
Clinical Features
Figure 42-1
Histopathologic Characteristics
Figure 42-2
Figure 42-3
Treatment
References
Chapter 43: Myofibroblastic Sarcoma
Clinical Features
Figure 43-1
Histopathologic Characteristics
Figure 43-2
Treatment
References
Chapter 44: Smooth Muscle Hamartoma
Clinical Features
Figure 44-1
Figure 44-2
Figure 44-3
Figure 44-4
Histopathologic Characteristics
Figure 44-5
Treatment
References
Chapter 45: Piloleiomyoma
Clinical Features
Figure 45-1
Figure 45-2
Figure 45-3
Figure 45-4
Figure 45-5
Histopathologic Characteristics
Figure 45-6
Figure 45-7
Treatment
References
Chapter 46: Angioleiomyoma
Chapter 46 Introduction
Clinical Features
Figure 46-1
Figure 46-2
Figure 46-3
Histopathologic Characteristics
Figure 46-4
Figure 46-5
Treatment
References
Chapter 47: Cutaneous Angiolipoleiomyoma
Clinical Features
Figure 47-1
Figure 47-2
Table 47-1: Differential Diagnosis between Angiolipoleiomyoma of the Kidney and Cutaneous
Angiolipoleiomyoma
Histopathologic Characteristics
Figure 47-3
Treatment
References
Chapter 48: Leiomyomas of the External Genitalia
Chapter 48 Introduction
Clinical Features
Figure 48-1
Figure 48-2
Figure 48-3
Histopathologic Characteristics
Figure 48-4
Figure 48-5
Figure 48-6
Treatment
References
Chapter 49: Cutaneous Leiomyosarcoma
Chapter 49 Introduction
Clinical Features
Figure 49-1
Figure 49-2
Histopathologic Characteristics
Figure 49-3
Figure 49-4
Figure 49-5
Treatment
References
Chapter 50: Striated Muscle Hamartoma (Rhabdomyomatous Mesenchymal Hamartoma)
Clinical Features
Figure 50-1
Histopathologic Characteristics
Figure 50-2
Treatment
References
Chapter 51: Extracardiac Rhabdomyoma
Chapter 51 Introduction
Adult Rhabdomyoma
Clinical Features
Histopathologic Characteristics
Treatment
Figure 51-1
Figure 51-2
Fetal Rhabdomyoma
Clinical Features
Histopathologic Characteristics
Treatment
Figure 51-3
Genital Rhabdomyoma
Clinical Features
Histopathologic Characteristics
Treatment
References
Chapter 52: Cutaneous Rhabdomyosarcoma
Clinical Features
Figure 52-1
Figure 52-2
Histopathologic Characteristics
Figure 52-3
Figure 52-4
Figure 52-5
Figure 52-6
Figure 52-6
Figure 52-6
Treatment and Prognosis
References
Section 3: Vascular Tumors
Chapter 53: Histology of Cutaneous Vascularization and Classification of Cutaneous Vascular Anomalies
Chapter 53 Introduction
Figure 53-1
Figure 53-2
Special Techniques for the Histopathologic Study of Vessels and Vascular Tumors
Immunohistochemical Studies
Figure 53-3
Figure 53-4
Figure 53-5
Figure 53-6
Figure 53-7
Figure 53-8
Figure 53-9
Figure 53-10
Figure 53-11
Figure 53-12
Figure 53-13
Molecular Biology Techniques
Figure 53-14
Figure 53-15
Cytogenetic Studies
Figure 53-16
Classification of Cutaneous Vascular Proliferations
Table 53-1: Classification of Benign and Malignant Vascular Skin Lesions
Table 53-2: Classification of Cutaneous Vascular Malformations According to Their Flow Characteristics and
Vascular Component
References
Chapter 54: Phakomatosis Pigmentovascularis
Clinical Features
Table 54-1: Classic Classification of Phakomatosis Pigmentovascularis
Figure 54-1
Figure 54-2
Figure 54-3
Figure 54-4
Histopathologic Characteristics
Figure 54-5
Treatment
References
Chapter 55: Eccrine Angiomatous Hamartoma
Chapter 55 Introduction
Clinical Features
Figure 55-1
Figure 55-2
Figure 55-3
Histopathologic Characteristics
Figure 55-4
Figure 55-5
Figure 55-6
Treatment
References
Chapter 56: Nevus Anemicus
Clinical Features
Figure 56-1
Figure 56-2
Figure 56-3
Histopathologic Characteristics
Treatment
References
Chapter 57: Cutis Marmorata Telangiectatica Congenita
Chapter 57 Introduction
Clinical Features
Figure 57-1
Figure 57-2
Figure 57-3
Figure 57-4
Histopathologic Characteristics
Figure 57-5
Treatment
References
Chapter 58: Salmon Patch and Port-Wine Stain or Nevus Flammeus
Chapter 58 Introduction
Clinical Features
Figure 58-1
Figure 58-2
Figure 58-3
Figure 58-4
Figure 58-5
Figure 58-6
Figure 58-7
Figure 58-8
Figure 58-9
Figure 58-10
Figure 58-11
Figure 58-12
Figure 58-13
Histopathologic Characteristics
Figure 58-14
Treatment
Figure 58-15
References
Chapter 59: Cutaneous Venous, Glomus, and Arteriovenous Malformations
Chapter 59 Introduction
Clinical Features
Figure 59-1
Figure 59-2
Figure 59-3
Figure 59-4
Figure 59-5
Figure 59-6
Figure 59-7
Histopathologic Characteristics
Figure 59-8
Treatment
Arteriovenous Malformations
Clinical Features
Histopathologic Characteristics
Figure 59-9
Treatment
References
Chapter 60: Cutaneous Lymphatic Malformations
Chapter 60 Introduction
Microcystic Cutaneous Lymphatic Malformations
Clinical Features
Histopathologic Characteristics
Treatment
Figure 60-1
Figure 60-2
Figure 60-3
Figure 60-4
Figure 60-5
Figure 60-6
Figure 60-7
Macrocystic Cutaneous Lymphatic Malformations (Cystic Hygromas)
Clinical Features
Histopathologic Characteristics
Treatment
Figure 60-8
Figure 60-9
Lymphangiomatosis
Clinical Features
Histopathologic Characteristics
Treatment
Figure 60-10
Figure 60-11
References
Chapter 61: Vascular Spider (Nevus Araneus)
Clinical Features
Figure 61-1
Figure 61-2
Figure 61-3
Figure 61-4
Histopathologic Characteristics
Figure 61-5
Treatment
References
Chapter 62: Caliber-Persistent Artery
Clinical Features
Figure 62-1
Histopathologic Characteristics
Figure 62-2
Treatment
References
Chapter 63: Capillary Aneurysm and Venous Lake
Chapter 63 Introduction
Clinical Features
Figure 63-1
Figure 63-2
Figure 63-3
Figure 63-4
Figure 63-5
Histopathologic Characteristics
Figure 63-6
Figure 63-7
Treatment
References
Chapter 64: Telangiectases
Chapter 64 Introduction
Figure 64-1
Figure 64-2
Unilateral Nevoid Telangiectasia
Figure 64-3
Generalized Essential Telangiectasia
Figure 64-4
Figure 64-5
Hereditary Hemorrhagic Telangiectasia
Figure 64-6
Figure 64-7
Figure 64-8
Figure 64-9
Figure 64-10
Hereditary Benign Telangiectasia
Ataxia Telangiectasia or Louis-Bar Syndrome
Figure 64-11
Figure 64-12
Cutaneous Collagenous Vasculopathy
Figure 64-13
Histopathologic Characteristics
Figure 64-14
Figure 64-15
Treatment
References
Chapter 65: Angiokeratomas
Chapter 65 Introduction
Clinical Features
Figure 65-1
Figure 65-2
Figure 65-3
Figure 65-4
Figure 65-5
Figure 65-6
Figure 65-7
Figure 65-8
Figure 65-9
Figure 65-10
Figure 65-11
Histopathologic Characteristics
Figure 65-12
Figure 65-13
Treatment
References
Chapter 66: Verrucous Hemangioma
Chapter 66 Introduction
Clinical Features
Figure 66-1
Figure 66-2
Histopathologic Characteristics
Figure 66-3
Figure 66-4
Figure 66-4
Figure 66-4
Treatment
References
Chapter 67: Lymphangiectases
Clinical Features
Figure 67-1
Figure 67-2
Histopathologic Characteristics
Figure 67-3
Treatment
References
Chapter 68: Angiolymphoid Hyperplasia with Eosinophilia
Chapter 68 Introduction
Clinical Features
Figure 68-1
Figure 68-2
Figure 68-3
Figure 68-4
Histopathologic Characteristics
Figure 68-5
Figure 68-6
Treatment
References
Chapter 69: Pyogenic Granuloma
Chapter 69 Introduction
Clinical Features
Figure 69-1
Figure 69-2
Figure 69-3
Figure 69-4
Figure 69-5
Figure 69-6
Figure 69-7
Figure 69-8
Histopathologic Characteristics
Figure 69-9
Figure 69-10
Figure 69-11
Figure 69-12
Figure 69-13
Treatment
References
Chapter 70: Bacillary Angiomatosis
Chapter 70 Introduction
Clinical Features
Figure 70-1
Figure 70-2
Histopathologic Characteristics
Figure 70-3
Figure 70-4
Figure 70-5
Treatment
References
Chapter 71: Verruga Peruana
Chapter 71 Introduction
Clinical Features
Figure 71-1
Figure 71-2
Histopathologic Characteristics
Figure 71-3
Treatment
References
Chapter 72: Cutaneous Epithelioid Angiomatous Nodule
Chapter 72 Introduction
Clinical Features
Figure 72-1
Histopathologic Characteristics
Figure 72-2
Treatment
References
Chapter 73: Reactive Angioendotheliomatosis
Chapter 73 Introduction
Clinical Features
Figure 73-1
Figure 73-2
Figure 73-3
Figure 73-4
Figure 73-5
Figure 73-6
Figure 73-7
Figure 73-8
Histopathologic Characteristics
Figure 73-9
Figure 73-10
Figure 73-11
Treatment
References
Chapter 74: Intralymphatic Histiocytosis
Chapter 74 Introduction
Clinical Features
Figure 74-1
Histopathologic Characteristics
Figure 74-2
Figure 74-2
Figure 74-2
Treatment
References
Chapter 75: Intravascular Papillary Endothelial Hyperplasia (Masson Pseudoangiosarcoma)
Chapter 75 Introduction
Clinical Features
Figure 75-1
Figure 75-2
Figure 75-3
Histopathologic Characteristics
Figure 75-4
Figure 75-5
Treatment
References
Chapter 76: Pseudo-Kaposi Sarcoma
Chapter 76 Introduction
Clinical Features
Figure 76-1
Figure 76-2
Figure 76-3
Figure 76-4
Figure 76-5
Histopathologic Characteristics
Figure 76-6
Figure 76-7
Figure 76-8
Treatment
References
Chapter 77: Serpiginous Angioma
Chapter 77 Introduction
Clinical Features
Figure 77-1
Figure 77-2
Figure 77-3
Figure 77-4
Figure 77-5
Histopathologic Characteristics
Figure 77-6
Treatment
References
Chapter 78: Infantile Hemangiomas
Chapter 78 Introduction
Clinical Features
Figure 78-1
Figure 78-2
Figure 78-3
Figure 78-4
Figure 78-5
Figure 78-6
Figure 78-7
Figure 78-8
Figure 78-9
Figure 78-10
Figure 78-11
Histopathologic Characteristics
Figure 78-12
Figure 78-13
Figure 78-14
Figure 78-15
Figure 78-16
Figure 78-17
Treatment
References
Chapter 79: Senile Hemangioma
Clinical Features
Figure 79-1
Figure 79-2
Histopathologic Characteristics
Figure 79-3
Treatment
References
Chapter 80: Acral Arteriovenous Hemangioma
Chapter 80 Introduction
Clinical Features
Figure 80-1
Figure 80-2
Figure 80-3
Figure 80-4
Figure 80-5
Histopathologic Characteristics
Figure 80-6
Figure 80-7
Treatment
References
Chapter 81: Hobnail Hemangioma (Targetoid Hemosiderotic Hemangioma)
Chapter 81 Introduction
Clinical Features
Figure 81-1
Figure 81-2
Figure 81-3
Figure 81-4
Figure 81-5
Histopathologic Characteristics
Figure 81-6
Figure 81-7
Figure 81-8
Treatment
References
Chapter 82: Microvenular Hemangioma
Chapter 82 Introduction
Clinical Features
Figure 82-1
Figure 82-2
Histopathologic Characteristics
Figure 82-3
Figure 82-4
Treatment
References
Chapter 83: Tufted Hemangioma
Chapter 83 Introduction
Clinical Features
Figure 83-1
Figure 83-2
Figure 83-3
Histopathologic Characteristics
Figure 83-4
Figure 83-5
Treatment
References
Chapter 84: Glomeruloid Hemangioma
Chapter 84 Introduction
Clinical Features
Figure 84-1
Histopathologic Characteristics
Figure 84-2
Figure 84-3
Treatment
References
Chapter 85: Acquired Elastotic Hemangioma
Clinical Features
Figure 85-1
Histopathologic Characteristics
Figure 85-2
Treatment
References
Chapter 86: Sinusoidal Hemangioma
Clinical Features
Figure 86-1
Histopathologic Characteristics
Figure 86-2
Figure 86-3
Treatment
References
Chapter 87: Spindle Cell Hemangioma
Chapter 87 Introduction
Clinical Features
Figure 87-1
Figure 87-2
Histopathologic Characteristics
Figure 87-3
Figure 87-4
Figure 87-5
Treatment
References
Chapter 88: Benign Lymphangioendothelioma
Chapter 88 Introduction
Clinical Features
Figure 88-1
Figure 88-2
Figure 88-3
Figure 88-4
Histopathologic Characteristics
Figure 88-5
Treatment
References
Chapter 89: Atypical Postradiation Vascular Lesions of the Skin
Chapter 89 Introduction
Clinical Features
Figure 89-1
Figure 89-2
Histopathologic Characteristics
Figure 89-3
Figure 89-4
Figure 89-5
Figure 89-6
Treatment
References
Chapter 90: Glomus Tumors
Clinical Features
Figure 90-1
Figure 90-2
Figure 90-3
Figure 90-4
Figure 90-5
Histopathologic Characteristics
Figure 90-6
Figure 90-7
Figure 90-8
Treatment
References
Chapter 91: Kaposi Sarcoma
Chapter 91 Introduction
Clinical Features
Figure 91-1
Figure 91-2
Figure 91-3
Figure 91-4
Figure 91-5
Figure 91-6
Figure 91-7
Figure 91-8
Figure 91-9
Figure 91-10
Figure 91-11
Histopathologic Characteristics
Figure 91-12
Figure 91-13
Figure 91-14
Figure 91-15
Figure 91-16
Figure 91-16
Figure 91-16
Figure 91-16
Treatment
References
Chapter 92: Kaposiform Hemangioendothelioma
Clinical Features
Figure 92-1
Figure 92-2
Figure 92-3
Histopathologic Characteristics
Figure 92-4
Figure 92-5
Figure 92-6
Treatment
References
Chapter 93: Papillary Intralymphatic Angioendothelioma (PILA) (Dabska Tumor)
Clinical Features
Figure 93-1
Histopathologic Characteristics
Figure 93-2
Figure 93-3
Treatment
References
Chapter 94: Retiform Hemangioendothelioma
Clinical Features
Figure 94-1
Histopathologic Characteristics
Figure 94-2
Figure 94-3
Treatment
References
Chapter 95: Epithelioid Hemangioendothelioma
Chapter 95 Introduction
Table 95-1: Suggested Terms for Neoplasms Currently Classified as Hemangioendothelioma
Clinical Features
Figure 95-1
Histopathologic Characteristics
Figure 95-2
Figure 95-3
Figure 95-4
Treatment
References
Chapter 96: Pseudomyogenic Hemangioendothelioma
Chapter 96 Introduction
Clinical Features
Figure 96-1
Histopathologic Characteristics
Figure 96-2
Figure 96-3
Figure 96-4
Treatment
References
Chapter 97: Composite Hemangioendothelioma
Clinical Features
Figure 97-1
Histopathologic Characteristics
Figure 97-2
Figure 97-3
Treatment
References
Chapter 98: Cutaneous Angiosarcoma of the Face and Scalp in Elderly Patients (Wilson Jones Angiosarcoma)
Chapter 98 Introduction
Clinical Features
Figure 98-1
Figure 98-2
Figure 98-3
Figure 98-4
Figure 98-5
Figure 98-6
Figure 98-7
Figure 98-8
Figure 98-9
Histopathologic Characteristics
Figure 98-10
Figure 98-11
Figure 98-12
Figure 98-13
Figure 98-14
Figure 98-14
Figure 98-14
Figure 98-15
Figure 98-16
Figure 98-17
Treatment
References
Chapter 99: Cutaneous Angiosarcoma with Associated Lymphedema
Chapter 99 Introduction
Clinical Features
Figure 99-1
Figure 99-2
Figure 99-3
Figure 99-4
Figure 99-5
Figure 99-6
Histopathologic Characteristics
Figure 99-7
Figure 99-8
Treatment
References
Chapter 100: Postirradiation Cutaneous Angiosarcoma
Chapter 100 Introduction
Clinical Features
Figure 100-1
Figure 100-2
Figure 100-3
Figure 100-4
Figure 100-5
Histopathologic Characteristics
Figure 100-6
Figure 100-7
Treatment
References
Chapter 101: Epithelioid Angiosarcoma
Clinical Features
Figure 101-1
Histopathologic Characteristics
Figure 101-2
Figure 101-3
Figure 101-4
Treatment
References
Chapter 102: Malignant Glomus Tumor (Glomangiosarcoma)
Chapter 102 Introduction
Clinical Features
Figure 102-1
Histopathologic Characteristics
Figure 102-2
Figure 102-3
Figure 102-3
Figure 102-3
Treatment
References
Chapter 103: Multinucleate Cell Angiohistiocytoma
Clinical Features
Figure 103-1
Figure 103-2
Histopathologic Characteristics
Figure 103-3
Treatment
References
Chapter 104: Angiofibroma
Chapter 104 Introduction
Clinical Features
Figure 104-1
Figure 104-2
Figure 104-3
Histopathologic Characteristics
Figure 104-4
Figure 104-5
Treatment
References
Chapter 105: Aggressive Angiomyxoma
Clinical Features
Figure 105-1
Histopathologic Characteristics
Figure 105-2
Treatment
References
Chapter 106: Kimura Disease
Clinical Features
Figure 106-1
Histopathologic Characteristics
Figure 106-2
Treatment
References
Chapter 107: Pseudolymphomatous Angiokeratoma in Children
Clinical Features
Figure 107-1
Histopathologic Characteristics
Figure 107-2
Treatment
References
Section 4: Neural Tumors
Chapter 108: Histology, Ultrastructure, and Immunohistochemistry of Peripheral Nerves: Classification of
Skin Tumors of Neural Origin
Histology and Ultrastructure of Peripheral Nerves
Figure 108-1
Figure 108-2
Figure 108-3
Figure 108-4
Immunohistochemistry of Peripheral Nerves
Figure 108-5
Figure 108-6
Figure 108-7
Specialized Cutaneous Nerve Endings
Figure 108-8
Figure 108-9
Classification of Skin Tumors of Neural Differentiation
Table 108-1: Classification of Skin Proliferations with Neural Differentiation
References
Chapter 109: Neural Hamartomas
Chapter 109 Introduction
Neuromuscular Hamartoma
Clinical Features
Histopathologic Characteristics
Treatment
Figure 109-1
Figure 109-2
Fibrolipomatous Hamartoma of Nerve (Neural Fibrolipoma)
Clinical Features
Histopathologic Characteristics
Treatment
Figure 109-3
Figure 109-4
Congenital Neurovascular Hamartoma of the Skin
Clinical Features
Histopathologic Characteristics
Treatment
Meningothelial Hamartoma
Clinical Features
Histopathologic Characteristics
Treatment
Figure 109-5
Figure 109-6
Figure 109-7
Congenital Neural Hamartoma (Fascicular Schwannoma)
Clinical Features
Histopathologic Characteristics
Treatment
Figure 109-8
Neurofollicular Hamartoma
Clinical Features
Histopathologic Characteristics
Treatment
Figure 109-9
Figure 109-10
References
Chapter 110: Hyperplasia of Pacini Corpuscles
Chapter 110 Introduction
Clinical Features
Figure 110-1
Histopathologic Characteristics
Figure 110-2
Treatment
References
Chapter 111: Glial Heterotopia (Nasal Glioma)
Chapter 111 Introduction
Clinical Features
Figure 111-1
Histopathologic Characteristics
Figure 111-2
Figure 111-3
Treatment
References
Chapter 112: Meningeal Heterotopia (Cutaneous Meningioma)
Chapter 112 Introduction
Clinical Features
Histopathologic Characteristics
Treatment
Figure 112-1
Figure 112-2
Figure 112-3
Figure 112-4
References
Chapter 113: Neuromas
Chapter 113 Introduction
Traumatic or Amputation Neuroma
Clinical Features
Histopathologic Characteristics
Treatment
Figure 113-1
Figure 113-2
Figure 113-3
Figure 113-4
Figure 113-4
Figure 113-4
Figure 113-4
Solitary Circumscribed Neuroma
Clinical Features
Histopathologic Characteristics
Treatment
Figure 113-5
Figure 113-6
Figure 113-7
Figure 113-8
Figure 113-9
Figure 113-10
Figure 113-11
Multiple Mucosal Neuromas
Clinical Features
Histopathologic Characteristics
Treatment
Figure 113-12
Figure 113-13
Figure 113-14
References
Chapter 114: Neurofibroma and Neurofibromatosis
Chapter 114 Introduction
Clinical Features
Figure 114-1
Figure 114-2
Figure 114-3
Figure 114-4
Table 114-1: Neurofibromatosis Types According to Riccardi
Figure 114-5
Figure 114-6
Figure 114-7
Figure 114-8
Figure 114-9
Figure 114-10
Figure 114-11
Figure 114-12
Figure 114-13
Figure 114-14
Figure 114-15
Figure 114-16
Histopathologic Characteristics
Figure 114-17
Figure 114-18
Figure 114-19
Figure 114-20
Figure 114-21
Figure 114-22
Figure 114-23
Treatment
References
Chapter 115: Schwannoma
Chapter 115 Introduction
Clinical Features
Figure 115-1
Figure 115-2
Figure 115-3
Histopathologic Characteristics
Figure 115-4
Figure 115-5
Figure 115-6
Figure 115-7
Figure 115-8
Figure 115-9
Figure 115-10
Figure 115-11
Figure 115-12
Figure 115-13
Treatment
References
Chapter 116: Granular Cell Tumor
Chapter 116 Introduction
Clinical Features
Figure 116-1
Figure 116-2
Histopathologic Characteristics
Figure 116-3
Figure 116-4
Figure 116-5
Figure 116-6
Treatment
References
Chapter 117: Nerve Sheath Myxoma and Neurothekeoma
Chapter 117 Introduction
Clinical Features
Figure 117-1
Figure 117-2
Figure 117-3
Histopathologic Characteristics
Figure 117-4
Figure 117-5
Figure 117-6
Figure 117-7
Figure 117-7
Figure 117-7
Treatment
References
Chapter 118: Perineurioma
Chapter 118 Introduction
Clinical Features
Figure 118-1
Figure 118-2
Histopathologic Characteristics
Figure 118-3
Figure 118-4
Figure 118-5
Figure 118-6
Figure 118-6
Figure 118-6
Treatment
References
Chapter 119: Cutaneous Ganglioneuroma
Clinical Features
Histopathologic Characteristics
Figure 119-1
Figure 119-2
Figure 119-3
Treatment
References
Chapter 120: Malignant Peripheral Nerve Sheath Tumor
Chapter 120 Introduction
Clinical Features
Figure 120-1
Histopathologic Characteristics
Figure 120-2
Figure 120-3
Figure 120-4
Figure 120-5
Figure 120-6
Figure 120-7
Treatment
References
Chapter 121: Primary Primitive Neuroectodermal Cutaneous Tumor
Chapter 121 Introduction
Clinical Features
Figure 121-1
Figure 121-2
Histopathologic Characteristics
Figure 121-3
Figure 121-4
Treatment
References
Chapter 122: Malignant Granular Cell Tumor
Clinical Features
Figure 122-1
Histopathologic Characteristics
Treatment
Figure 122-2
Figure 122-2
Figure 122-2
Figure 122-2
References
Section 5: Adipose Tumors
Chapter 123: Histology of Normal Subcutis and Classification of Adipose Proliferations
Anatomy and Histology of Normal Subcutis
Figure 123-1
Classification of Skin Proliferations with Adipocytic Differentiation
Table 123-1: Classification of Skin Proliferations with Adipocytic Differentiation
Table 123-2: Chromosomal Abnormalities Described in Benign Adipocyte Proliferations
References
Chapter 124: Piezogenic Papules
Clinical Features
Figure 124-1
Histopathologic Characteristics
Figure 124-2
Treatment
References
Chapter 125: Nevus Lipomatosus Cutaneous Superficialis
Chapter 125 Introduction
Clinical Features
Figure 125-1
Histopathologic Characteristics
Figure 125-2
Treatment
References
Chapter 126: Fibrolipomatous Hamartoma of the Nerve
Clinical Features
Figure 126-1
Histopathologic Characteristics
Figure 126-2
Treatment
References
Chapter 127: Lipomas and Lipomatosis
Clinical Features
Figure 127-1
Figure 127-2
Table 127-1: Disorders Associated with Multiple Lipomas
Figure 127-3
Figure 127-4
Figure 127-5
Figure 127-6
Figure 127-7
Figure 127-8
Table 127-2: Drugs Reported to be Capable of Causing Lipomas
Histopathologic Characteristics
Figure 127-9
Figure 127-10
Figure 127-11
Figure 127-12
Treatment
References
Chapter 128: Angiolipoma
Clinical Features
Figure 128-1
Histopathologic Characteristics
Figure 128-2
Figure 128-3
Treatment
References
Chapter 129: Chondroid Lipoma
Chapter 129 Introduction
Clinical Features
Figure 129-1
Histopathologic Characteristics
Figure 129-2
Treatment
References
Chapter 130: Spindle Cell Lipoma/Pleomorphic Lipoma
Chapter 130 Introduction
Clinical Features
Figure 130-1
Histopathologic Characteristics
Figure 130-2
Figure 130-3
Figure 130-4
Figure 130-5
Figure 130-6
Treatment
References
Chapter 131: Lipofibromatosis
Chapter 131 Introduction
Clinical Features
Figure 131-1
Histopathologic Characteristics
Figure 131-2
Treatment
References
Chapter 132: Hemosiderotic Fibrolipomatous Tumor
Chapter 132 Introduction
Clinical Features
Histopathologic Characteristics
Figure 132-1
Treatment
References
Chapter 133: Lipoblastoma and Lipoblastomatosis
Chapter 133 Introduction
Clinical Features
Figure 133-1
Histopathologic Characteristics
Figure 133-2
Figure 133-3
Treatment
References
Chapter 134: Hibernoma
Chapter 134 Introduction
Clinical Features
Figure 134-1
Histopathologic Characteristics
Figure 134-2
Treatment
References
Chapter 135: Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma
Chapter 135 Introduction
Clinical Features
Figure 135-1
Figure 135-2
Figure 135-2
Figure 135-2
Histopathologic Characteristics
Figure 135-3
Treatment
References
Chapter 136: Undifferentiated Liposarcoma
Chapter 136 Introduction
Clinical Features
Figure 136-1
Histopathologic Characteristics
Figure 136-2
Other Histopathologic Variants of Liposarcoma
Figure 136-3
Figure 136-4
Figure 136-5
Figure 136-5
Figure 136-5
Treatment
References
Section 6: Cartilage Tumors
Chapter 137: Histology of Normal Cartilage and Classification of Cartilaginous Lesions of the Skin
Histology of Normal Cartilage
Figure 137-1
Classification of Skin Proliferations with Cartilaginous Differentiation
Table 137-1: Classification of Skin Proliferations with Cartilaginous Differentiation
References
Chapter 138: Accessory Tragus
Clinical Features
Figure 138-1
Histopathologic Characteristics
Figure 138-2
Treatment
References
Chapter 139: Extraskeletal Chondroma
Chapter 139 Introduction
Clinical Features
Figure 139-1
Histopathologic Characteristics
Figure 139-2
Treatment
References
Chapter 140: Subungual Osteochondroma (Subungual Exostosis)
Clinical Features
Table 140-1: Criteria for Differentiation between Subungual Exostosis and Subungual Osteochondroma
Figure 140-1
Histopathologic Characteristics
Figure 140-2
Treatment
References
Section 7: Ossifying Tumors
Chapter 141: Normal Bone Histology and Classification of Ossifying Lesions Presenting in the Skin
Normal Bone Histology
Figure 141-1
Classification of Ossifying Lesions Presenting in the Skin
Table 141-1: Classification of Cutaneous and Subcutaneous Tumors with Osseous Differentiation
References
Chapter 142: Osteoma Cutis
Clinical Features
Table 142-1: Classification of Cutaneous Ossifications
Figure 142-1
Histopathologic Characteristics
Figure 142-2
Treatment
References
Chapter 143: Fibro-Osseous Pseudotumor of the Digits
Clinical Features
Figure 143-1
Histopathologic Characteristics
Figure 143-2
Treatment
References
Chapter 144: Ossifying Plexiform Tumor
Clinical Features
Figure 144-1
Histopathologic Characteristics
Figure 144-2
Treatment
References
Chapter 145: Ossifying Fibromyxoid Tumor
Clinical Features
Figure 145-1
Histopathologic Characteristics
Figure 145-2
Treatment
References
Chapter 146: Extraskeletal Osteosarcoma
Clinical Features
Figure 146-1
Histopathologic Characteristics
Figure 146-2
Treatment
References
Section 8: Myoepithelial Tumors
Chapter 147: Myoepithelioma and Myoepithelial Carcinoma
Chapter 147 Introduction
Clinical Characteristics
Figure 147-1
Histopathologic Characteristics
Figure 147-2
Figure 147-3
Figure 147-4
Figure 147-5
Treatment
References
Section 9: Melanocytic Tumors
Chapter 148: Cutaneous Clear Cell Sarcoma
Chapter 148 Introduction
Clinical Features
Figure 148-1
Histopathologic Characteristics
Figure 148-2
Figure 148-2
Figure 148-2
Figure 148-2
Figure 148-2
Figure 148-3
Treatment
References
Section 10: Tumors of Unknown Histogenesis
Chapter 149: Primary Cutaneous Ewing Sarcoma
Chapter 149 Introduction
Clinical Features
Figure 149-1
Histopathologic Characteristics
Figure 149-2
Figure 149-2
Figure 149-2
Table 149-1: Chromosomal Rearrangements Found in Ewing Sarcoma and “Ewing-Like Sarcoma”
References
Appendix
Remarks