Lung Cancer:Part I-1판

This issue of Clinics in Chest Medicine guest-edited by Dr. M. Patricia Rivera is the first of two issues
focused on Lung Cancer. Topics discussed in this issue include but are not limited to: Lung Cancer in the
21st Century; Epidemiology Etiology and Prevention; Lung Cancer in Women: A Modern Epidemic; Primary
Prevention of Lung Cancer: Tobacco Treatment; The Biology of Lung Cancer: Development of More Effective
Methods for Prevention Diagnosis and Treatment; Pathology of Lung Cancer; Lung Cancer Screening: Patient
Selection and Implementation; The Approach to the Subsolid Nodule; Bronchoscopic Diagnostic Procedures
Available to the Pulmonologist; Bronchoscopic Therapeutic Procedures Available to the Pulmonologist; and
Biomarkers in Lung Cancer.

Author Information
Edited by M. Patricia Rivera, MD, Division of Pulmonary and Critical Care, Department of Medicine, The
University of North Carolina at Chapel Hill, NC


Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Lung Cancer 2020: Epidemiology, Etiology, and Prevention
Key points
Epidemiology of lung cancer
Etiology and prevention of lung cancer
Summary
The Biology of Lung Cancer: Development of More Effective Methods for Prevention, Diagnosis, and Treatment
Key points
Introduction: the biology of lung cancer
Development of more effective methods for prevention, diagnosis, and treatment
Summary
Primary and Secondary Prevention of Lung Cancer: Tobacco Treatment
Key points
Introduction
Benefits to incorporating tobacco treatment into the lung cancer care continuum
Barriers to tobacco treatment in the lung cancer care continuum
Guideline-recommended pharmacotherapy and counseling
Role of harm reduction approaches in tobacco dependence treatment
Summary
Lung Cancer in Women: A Modern Epidemic
Key points
Introduction
Epidemiology of lung cancer in women
Differences in lung cancer risk between men and women
Biologic factors
Additional risk factors
Histologic distribution of lung cancer in women
Treatment response, complication, and outcomes
Lung cancer screening
Impact of tobacco cessation
Summary
Lung Cancer Pathology: Current Concepts
Key points
Introduction
Lung cancer classification in small biopsies and cytology
Preinvasive lesions
Adenocarcinoma
Squamous cell carcinoma
Neuroendocrine lung tumors
Small cell carcinoma
Combined small cell lung cancer
Large cell neuroendocrine carcinoma
Typical and atypical carcinoid tumors
Large cell carcinoma
Adenosquamous carcinoma
Sarcomatoid carcinomas
Carcinosarcoma and pulmonary blastoma
Lung Cancer Screening: Patient Selection and Implementation
Key points
Introduction
Evidence for lung cancer screening
Patient selection for lung cancer screening
Implementation of lung cancer screening
Future
Summary
Approach to the Subsolid Nodule
Key points
Introduction
The nature of ground glass nodules
How should we manage patients?
Treatment of ground glass nodules
Multifocal ground glass nodules
Summary
Biomarkers in Lung Cancer
Key points
Introduction
Biomarker development
Clinical utility evaluation
Current utilization of biomarkers
Current trends and future directions
Summary
Bronchoscopic Diagnostic Procedures Available to the Pulmonologist
Key points
Introduction
Flexible bronchoscopy
Convex (linear) probe endobronchial ultrasound뻝uided transbronchial needle aspiration
Approaches to sampling peripheral pulmonary lesions
Emerging technologies
Summary
Therapeutic Bronchoscopic Techniques Available to the Pulmonologist: Emerging Therapies in the Treatment
of Peripheral Lung Lesions and Endobronchial Tumors
Key points
Introduction
What patients benefit from therapeutic interventions to the central airways?
Does relieving central airway obstruction improve clinically meaningful outcomes?
What new and emerging therapies are available for the treatment of endobronchial tumors?
What options are available for the treatment of peripheral lung cancers by bronchoscopy?
Summary