Topics in Pediatric Transfusion Medicine-1판

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Transfusion in Pediatric Patients: Review of Evidence-Based Guidelines

Key points
Introduction
Red blood cells
Platelets
Plasma
Cryoprecipitate
Summary
Transfusion in Neonatal Patients: Review of Evidence-Based Guidelines

Key points
Introduction
Fetal and neonatal hematopoiesis
Neonatal red blood cell transfusion
Neonatal platelet transfusion
Neonatal plasma transfusion
Massive Transfusion in Pediatric Patients

Key points
Introduction
Epidemiology of life-threatening hemorrhage in children
Definition of massive transfusion in children
Indications for massive transfusion protocol activation
Complications of massive transfusion
Ratios of blood products
Barriers to massive transfusion protocol adherence and implementation
Whole blood
Adjuncts
Future directions
Pediatric Hemovigilance and Adverse Transfusion Reactions

Key points
Introduction
Hemovigilance systems
Acute transfusion reactions
Delayed transfusion reactions
Other
Component modifications and storage duration

Summary
Inventory Management and Product Selection in Pediatric Blood Banking

Key points
Process steps for active inventory management
Manufacturing aliquots
Special populations for inventory management
Evaluation and Management of Coagulopathies and Thrombophilias in Pediatric Patients

Key points
Introduction
Content
Evaluation and management of pediatric thrombosis

Summary
Transfusion and Cellular Therapy in Pediatric Sickle Cell Disease

Key points
Transfusion management of sickle cell disease
Allogeneic hematopoietic stem cell transplant and transfusion support
Complications of peri-hsct red blood cell transfusion
Autologous hematopoietic stem cell transplant and transfusion support

Summary
Cellular Therapy in Pediatric Hematologic Malignancies

Key points
Introduction
Hematopoietic stem cell transplant
Chimeric antigen receptor T-cell therapy
Regulatory T cells
Natural killer cell adoptive therapy
αβ and T-cell depletions
Regulatory considerations in the United States

Summary
Hemolytic Disease of the Fetus and Newborn: Historical and Current State

Key points
Introduction
History
Pathophysiology
Epidemiology
History of treatment
Current management
Current burden of care and future directions

Summary
Novel Blood Component Therapies in the Pediatric Setting

Key points
Introduction
Whole blood
Pathogen-reduced blood products
Fibrinogen concentrate

Summary