Introduction to pathology/primer
GOALs
The clinical practice of pathology
Surgical pathology: Inside the box
Neoplasia: Understanding benign and malignant
Gastrointesintal System, Liver, Pancreas
1. A 60-year-old male with a solid pancreatic mass
2. A 54-year-old female with back pain and an incidental pancreatic cystic mass found on CT-scan
3. A 41-year-old man with a liver mass
4. A 45-year-old woman with radiating epigastric pain
5. A 67-year-old male with dysphagia
6. A 45-year-old female with dyspepsia
7. A 52-year-old woman with an incidental terminal ileum mass
8. An 18-year-old male with right upper quadrant abdominal pain
9. A 68-year-old male with hematochezia
Female Genital System
10. A 77-year-old female presenting with a lesion in the vaginal area
11. A 26-year-old female patient presents with pap smear of atypical squamous cells of undetermined significance
(ASCUS)
12. A 61-year-old woman with postmenopausal bleeding
13. A 56-year-old female with pelvic mass
Male Genital System
14. A 37-year-old man with a left testicular swelling
Oral Cavity/ENT
15. A 72-year-old female with a white plaque on her left lateral tongue
16. A 49-year-old man with a neck mass
17. A 23-year-old female with swelling of her parotid region
18. A 72-year-old male with pressure sensation in his face
19. A 57-year-old man with swelling of his lip
Breast
20. A 51-year-old woman with a breast lump
21. A 46-year-old woman with a right breast mass and no other symptoms
22. A 63-year-old female presenting for annual screening
23. A 70-year-old male with a mass around his nipple
Genitourinary System
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24. A 68-year-old woman with a renal mass
The VHL gene and the hypoxia-inducible transcription factor (HIF) pathway
The PI3K/mammalian target of rapamycin (mTOR) pathway
The Birt-Hogg-Dubé syndrome
The mesenchymal–epithelial transition (MET) pathway
Genetic alterations in nephroblastoma (Wilms Tumor)
Clear cell renal cell carcinoma
Papillary renal cell carcinoma
Chromophobe renal cell carcinoma
Nephroblastoma (WT)
Oncocytoma
Angiomyolipoma
Secondary tumors
How are renal tumors treated?
Management of nephroblastoma
Management of benign tumors
25. A 63-year-old male with urinary frequency and gross hematuria
26. A 34-year-old male with edema
Respiratory System
27. A 75-year-old female with shortness of breath and chest pain
28. A 64-year-old male with progressive shortness of breath
29. A 70-year-old male with a history of increased shortness of breath
30. A 59-year-old male with productive cough
31. A 79-year-old woman with a pulmonary, right upper lobe mass
32. An 86-year-old male with cough and dyspnea on exertion
33. A 33-year-old female presenting with shortness of breath and cough
Musculoskeletal System
34. A 12-year-old male with right leg pain
35. A 50-year-old male with right shoulder mass and pain
36. A 30-year-old female with right foot mass
37. A 68-year-old woman with right thigh mass
38. An 18-year-old male with left knee pain and mass
Skin
39. A 61-year-old female with a pruritic rash
40. A 75-year-old male with a blistering skin rash
41. A 65-year-old female with a pre-auricular skin lesion
42. A 32-year-old female with a mole
Nervous System
43. A 70-year-old male with a brain mass
44. An 8-year-old female with brown macules and soft papules
45. An 85-year-old female with progressive dementia
Hematopoietic System
46. A 16-year-old female with fatigue, breathlessness, and pallor
47. A 62-year-old male with fatigue and weight loss
Endocrine System
48. A 35-year-old female with a midline neck mass and no other symptoms
49. A 69-year-old female with weakness, shortness of breath, and syncopal episodes
Index