Description:
With more international contributors than ever before, Block's Disinfection, Sterilization, and Preservation, 6th
Edition, is the first new edition in nearly 20 years of the definitive technical manual for anyone involved in
physical and chemical disinfection and sterilization methods. The book focuses on disease prevention-rather than
eradication-and has been thoroughly updated with new information based on recent advances in the field and
understanding of the risks, the technologies available, and the regulatory environments.
control of infection risks.
test methodologies, and more.
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PART I: INTRODUCTION
1. Historical Perspective
2. Definition of Terms
PART II: FUNDAMENTAL PRINCIPLES OF ACTIVITY
3. Microorganisms and Resistance
4. Bacterial Resistance to Biocides
5. Principles of Antimicrobial Activity
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6. The Impact of Formulary Components on Antimicrobial Products
7. Kinetics of the Inactivation of Microorganisms
8. Importance and Processes of Cleaning
PART III: DISINFECTION BY ANTIMICROBIAL TYPES
9. Ultraviolet Disinfection
10. Nonionizing Radiation: Microwave Radiation, Infrared Radiation, and Pulsed Light
11. Microbial Inactivation Kinetics and Heat Disinfection
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12. Acids and Alkalis
13. Antimicrobial Dyes
14. Essential Oils
15. Chlorine and Chlorine Compounds
16. Iodine and Iodine-Containing Compounds
17. Bromine and Bromine-Releasing Biocides
18. Peroxygen Compounds
19. Alcohols
20. Phenolic Compounds
21. Surface-Active Agents
22. Chlorhexidine
23. Aldehydes
24. Copper Alloy Surfaces Kill Bacteria and Reduce Infections
25. Silver and Silver Nanoparticles
26. Peptides, Enzymes, and Bacteriophages
27. Chlorine Dioxide
PART IV: STERILIZATION BY ANTIMICROBIAL TYPES
28. Sterilization and Depyrogenation by Heat
29. Sterilization and Preservation by Radiation
30. Sterile Filtration of Liquids and Gases
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31. Ethylene Oxide Sterilization
32. Disinfection and Sterilization With Hydrogen Peroxide
33. Disinfection and Sterilization Using Ozone
34. Plasma Sterilization
35. Nitrogen Dioxide
36. Formaldehyde
PART V: PRESERVATION
37. Prevention of Infection From Food and Water
38. Preservation of Industrial Products and Processes
39. Preservation of Pharmaceutical Dosage Forms
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40. Cosmetic Preservatives and Preservation
41. Sterile Packaging
PART VI: MEDICAL AND HEALTH-RELATED APPLICATIONS
42. Hand Hygiene
43. Surgical Antisepsis
44. Infection Prevention for Skin and Burns
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45. Oral and Mucous Membrane Treatments
46. Laundry Hygiene
47. Processing of Reusable Medical Devices
48. Targeted Decontamination of Environmental Surfaces in Everyday Settings
49. Basic Principles of Infection Prevention and Control
50. Disinfection and Sterilization of Living and Scaffold Tissue Engineered Medical Products
51. Sterilization, Disinfection, and Asepsis in Dentistry
52. Disinfection and Biosecurity in the Prevention and Control of Disease in Veterinary Medicine
53. Disinfection of Contact Lenses
54. Infectious Waste Management, Treatment, and Disposal
55. Reprocessing and Remanufacturing of Single-Use Medical Devices
PART VII: INDUSTRIAL AND RESEARCH APPLICATIONS
56. Food- and Waterborne Microorganisms
57. Groundwater Purification
58. Aseptic Processing and Facilities for the Control of Microbial Contamination
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59. Safe Handling of Biological Agents in the Laboratory
60. Control and Monitoring of Microbiological Quality in Nonsterile Manufacturing Facilities
PART VIII: METHODS OF TESTING
61. Disinfectant Efficacy Testing
62. Standard Microbiological Methods for Antimicrobial Products in North America
63. Antimicrobial Test Methods in the European Union
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64. Bioburden Assessment and Tests for Sterility
65. Biological Indicators, Chemical Indicators, and Parametric Release
PART IX: MISCELLANEOUS TOPICS
66. Bacterial Endotoxin
67. Biofilm and Biofilm Control
68. Prions
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69. Fungal Contamination in the Built Environment: Shipping and Storage
70. Regulation of Preservation, Disinfection, and Sterilization Agents, Equipment, and Processes
71. Federal Regulation of Liquid Chemical Germicides and Healthcare Sterilization by the US Food and Drug
Administration
72. Regulation of Antimicrobial Pesticides by the US Environmental Protection Agency
73. Antimicrobial Surfaces
74. Nanotechnology for Disinfection and Sterilization