Principles of Cancer Genetics-2판

This is the second edition of a widely used textbook that consolidates the basic concepts of the cancer gene theory and
provides a framework for understanding the genetic basis of cancer. Particular attention is devoted to the origins of
the mutations that cause cancer, and the application of evolutionary theory to explain how the cell clones that harbor
cancer genes tend to expand. Focused on the altered genes and pathways that cause the growth of the most common tumors,
Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory coursework in
genetics, biology and biochemistry, medical students and medical house staff. For students with a general interest in
cancer, this book provides a highly accessible and readable overview. For more advanced students contemplating future
study in the field of oncology and cancer research, this concise book will be useful as a primer.



Frontmatter
1. The Genetic Basis of Cancer
2. Oncogenes
3. Tumor Suppressor Genes
4. Genetic Instability and Cancer
5. Cancer Genomes
6. Cancer Gene Pathways
7. Genetic Alternations in Common Cancers
8. Cancer Genetics in the Clinic
Backmatter