Tumors of the Uterine Corpus and Gestational Trophoblastic Diseases

Description

AFIP Atlas: Tumors of the Uterine Corpus and Trophoblastic Diseases
Since the publication of the Third Series Fascicle of the Uterine Corpus nearly thirty years ago, molecular
discoveries have deepened our understanding of epithelial, mesenchymal, and mixed müllerian tumors of the uterus,
fueling a new and still evolving classification of the different categories of uterine neoplasms. Enormous insights
have been made to refine the classification of the different subtypes of endometrial carcinoma linked to important
prognostic and therapeutic implications.

At the same time, molecular findings have allowed for the discovery of familial syndromes associated with uterine
corpus neoplasms, and identification of patients at increased risk for developing specific tumors, with the
subsequent implementation of genetic counseling and appropriate treatment guidelines. Molecular underpinnings
have also assisted in the development of new and potentially more predictive morphologic criteria for endometrial
preneoplasia, namely the endometrial intraepithelial neoplasia (or EIN) system.
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