Goldfrank's Toxicologic Emergencies-11판

The best edition yet of the landmark text in medical toxicology
A Doody’s Core Title for 2019! 

Covering every aspect of poison management, this indispensable case-based resource has been thoroughly refreshed to 
deliver evidence-based principles viewed through the lens of an active bedside clinical practice. 
In no other reference will you find such a diverse roster of esteemed editors and authors who deliver expert insights 
into every type of toxicologic emergency, whether due to substance abuse or exposure to toxins. 

Fully referenced and supported by a cohesive organization and full-color format, Goldfrank’s begins with a historical 
perspective on medical toxicology principles and the general approach to the patient. 
It then progresses to the fundamental principles of medical toxicology, encompassing biochemical and molecular 
concepts; the effect of xenobiotics on vital organs and body systems; and toxicologic principles in special 
populations. 

The Eleventh Edition of Goldfrank’s Toxicologic Emergencies is the most rigorous volume to date, driven by a precise 
analysis of the latest medical literature and complex cases designed to facilitate differential diagnosis. 

New to this Edition: 
　　
Additional cases and “Special Considerations” chapters designed to enhance clinical decision-making and 
       patient outcomes
　　
New “Antidotes in Depth” provides timely, critical information on toxicologic treatment strategies 
　　
New content on toxicogenomics explores its increasingly important role in predictive toxicology
　　
Chapter-ending bulleted summaries of key points 
　　
Updated coverage of synthetics such as “K2” 
　　
Revised chapters on medical, clinical, and chemical toxicology include updated insights on poison emergencies, 
       treatment strategies, and risk assessment tools




 1. Historical Principles and Perspectives
 2. Toxicologic Misfortunes and Catastrophes in History

PART A　THE GENERAL APPROACH TO THE PATIENT 

 3. Initial Evaluation of the Patient: Vital Signs and Toxic Syndromes
 4. Principles of Managing the Acutely Poisoned or Overdosed Patient
　　-　SC1. Principles of Antidote Stocking
 5. Decontamination Principles: Prevention of Gastrointestinal Absorption
　　-　SC2. Decontamination Principles: Prevention of Dermal, Inhalational and Ocular Absorption
A1. Activated Charcoal

A2. Whole-Bowel Irrigation and Other Intestinal Evacuants

 6. Principles and Techniques Applied to Enhance Elimination
 7. Laboratory Principles
 8. Principles of Diagnostic Imaging
 9. Pharmacokinetic and Toxicokinetic Principles

PART　B　THE FUNDAMENTAL PRINCIPLES OF MEDICAL TOXICOLOGY
-　SECTION　I　BIOCHEMICAL AND MOLECULAR CONCEPTS 

 10. Chemical Principles
 11. Biochemical and Metabolic Principles
 12. Fluid, Electrolyte, and Acid쭯Base Principles
 13. Neurotransmitters and Neuromodulators
 14. Withdrawal Principles

-　SECTION　II　PATHOPHYSIOLOGIC BASIS: ORGAN SYSTEMS 
 15. Cardiologic Principles I: Electrophysiologic and Electrocardiographic Principles
 16. Cardiologic Principles II: Hemodynamics
 17. Dermatologic Principles
　　-　SC3. Transdermal Toxicology
 18. Gastrointestinal Principles
 19. Genitourinary Principles
 20. Hematologic Principles
 21. Hepatic Principles
 22. Neurologic Principles
 23. Oncologic Principles
 24. Ophthalmic Principles
 25. Otolaryngologic Principles
 26. Psychiatric Principles