Laryngeal Cancer

The definitive state-of-the-art guide on laryngeal cancer treatment from world-renowned experts

Ongoing advances in innovative technologies have improved the diagnosis and treatment of laryngeal cancer,
resulting in more optimal oncologic and functional patient outcomes. Laryngeal Cancer: Clinical Case-Based
Approaches, by distinguished head and neck surgeon Rogério R. Dedivitis and internationally recognized coeditors,
is a comprehensive reference that presents multiple options for similar lesions. Contributions from a diverse group of
globally renowned subspecialists reflect the multidisciplinary treatment of laryngeal cancer.

The book focuses on diverse primary subsites of laryngeal cancer; local, early-stage, and advanced disease stages;
and current available treatment modalities for each type. Case study chapters include insightful discussion of several
potential approaches, rationale for surgical decision making, radiographic findings, pearls, and pitfalls.

Key Features

　•　Diverse approaches to glottic cancer including radiotherapy, transoral laser surgery, supracricoid laryngectomy
　　 (SCL), vertical laryngectomy, transoral laser microsurgery, chemoradiotherapy, and combined SCL and
　　 cricohyoidoepiglottopexy.
　•　Treatment modalities for supraglottic cancers such as transoral laser microsurgery, radiation therapy, and
　　 horizontal supraglottic laryngectomy.
　•　Salvage surgery, preservation protocol, and reconstructive flap techniques including pectoralis major
　　 myocutaneous flap, latissimus dorsi myocutaneous flap, and antebrachial flap.
　•　High-quality images accompanying each case enhance clinical understanding of underlying pathologies and
　　 surgical approaches.

Otolaryngologist—head and neck surgeons, radiation oncologists, medical oncologists, pathologists, radiologists,
speech pathologists, and all clinicians who treat laryngeal disorders will benefit from this highly informative
resource.

This book includes complimentary access to a digital copy on https://medone.thieme.com.




1. T₁a Glottic Carcinoma Undergoing Transoral Laser Surgery
　1.1 Case Report
　1.2 Discussion
　1.3 Tips
　1.4 Traps

2. Radiotherapy for T₁a Glottic Cancer
　2.1 Case Presentation
　2.2 Discussion

3. Robotic Surgery for Early-Stage Laryngeal Cancer
　3.1 Case Report
　3.2 Discussion
　3.3 Tips
　3.4 Traps

4. T₁b Glottic Cancer Treated with Transoral Laser Surgery
　4.1 Clinical Case
　4.2 Discussion
　4.3 Tips
　4.4 Traps

5. T₁b Glottic Cancer
　5.1 Introduction
　5.2 Evaluation
　5.3 Selection of Treatment Modality
　5.4 Voice Quality
　5.5 Simulation and Planning
　5.6 Fractionation
　5.7 Long-term Considerations and Secondary Malignancy
　5.8 Smoking Cessation

6. T₁b Glottic Cancer, Vertical Partial Laryngectomy
　6.1 Case Report
　6.2 Discussiong
　6.3 Tips
　6.4 Traps

7. Transoral Laser Microsurgery for Intermediate Supraglottic Cancer
　7.1 Case Report
　7.2 Discussion
　7.3 Tips
　7.4 Traps

8. The Role of Radiation Therapy in Early-Stage Supraglottic Cancer
　8.1 Case Report
　8.2 Discussion
　8.3 Tips
　8.4 Traps

9. Early Supraglottic Cancer: Horizontal Supraglottic Laryngectomy
　9.1 Case Report
　9.2 Discussion
　9.3 Tips
　9.4 Traps

10. Locally Intermediate Glottic Cancer: Transoral Laser Microsurgery
　10.1 Case Report
　10.2 Discussion
　10.3 Tips
　10.4 Traps

11. Locally Intermediate Glottic Cancer: Chemoradiotherapy
　11.1 Case Report
　11.2 Discussion
　11.3 Tips
　11.4 Traps

12. Locally Intermediate Glottic Cancer: Vertical Partial Laryngectomy
　12.1 Case Report
　12.2 Discussion
　12.3 Tips
　12.4 Traps

13. Locally Intermediate Glottic Cancer: Supracricoid Laryngectomy with CHEP
　13.1 Clinical Case
　13.2 Discussiong
　13.3 Tips and Traps

14. Transoral Robotic Surgery for Advanced Laryngeal Cancer
　14.1 Introduction
　14.2 Schematic Overview of Treatment Protocol (TORS Combined with Induction Chemotherapy)
　14.3 Selection of Patients for Treatment Protocol
　14.4 Induction Chemotherapy Protocol
　14.5 Operative Procedure
　14.6 Adjuvant Treatment
　14.7 Treatment Outcomes
　14.8 Consideration

15. Locally Advanced Supraglottic Cancer: Larynx Preservation by Transoral Laser Microsurgery
　15.1 Case Presentation
　15.2 Discussion
　15.3 Conclusion
　15.4 Tips
　15.5 Traps

16. Locally Intermediate Supraglottic Cancer: Radiotherapy
　16.1 Case Report
　16.2 Discussion
　16.3 Tips
　16.4 Traps

17. Locally Intermediate Supraglottic Cancer: Supracricoid Laryngectomy with Cricohyoidopexy
　17.1 Case Report
　17.2 Discussion
　17.3 Tips
　17.4 Traps

18. Locally Advanced Glottic Cancer: Supracricoid Laryngectomy
　18.1 Case Report
　18.2 Discussion
　18.3 Tips
　18.4 Traps

19. Hemicricolaryngectomy with Tracheal Autotransplantation
　19.1 Case Report
　19.2 Discussion
　19.3 Tips
　19.4 Traps

20. Locally Advanced Glottic Cancer: Supratracheal Laryngectomy
　20.1 Clinical Case 1
　20.2 Clinical Case 2
　20.3 Discussiong
　20.4 Tips
　20.5 Traps

21. Locally Advanced Glottic Cancer: Total Laryngectomy and Voice Prostheses
　21.1 Case Report
　21.2 Discussion
　21.3 Tips
　21.4 Traps

22. Transoral Robotic Surgical Total Laryngectomy: The Technique Step by Step
　22.1 Introduction
　22.2 Patients and Methods
　22.3 Discussion
　22.4 Conclusion

23. Locally Advanced Supraglottic Cancer: Organ-Preservation Protocol
　23.1 Case Report
　23.2 Discussion

24. Salvage Surgery after Primary Radiotherapy: Transoral Laser Microsurgery
　24.1 Case Reports
　24.2 Discussion
　24.3 Tips
　24.4 Traps

25. Salvage Surgery after Radiotherapy: Supracricoid Laryngectomy
　25.1 Case Report
　25.2 Discussion
　25.3 Tips
　25.4 Traps

26. Salvage Surgery after Radiotherapy: Total Laryngectomy
　26.1 Case Report
　26.2 Surgical Technique
　26.3 Discussion
　26.4 Tips
　26.5 Traps

27. Strategy for Avoiding Pharyngocutaneous Fistula: Pectoralis Muscle Flap for Salvage Total Laryngectomy
　27.1 Case Report
　27.2 Discussion
　27.3 Tips
　27.4 Traps

28. Reconstruction for Advanced Cancer: Pectoralis Major Myocutaneous Flap
　28.1 Introduction
　28.2 Surgical Technique
　28.3 Primary Indications in the Treatment of Advanced Laryngeal Tumors
　28.4 Complications
　28.5 Functional Result
　28.6 Clinical Cases

29. Reconstruction for Advanced Cancer: Supraclavicular Island Flap
　29.1 Case Report
　29.2 Discussion
　29.3 Tips
　29.4 Traps

30. Reconstruction for Advanced Cancer: Latissimus Dorsi Myocutaneous Flap
　30.1 Case Report
　30.2 Discussiong
　30.3 Tips
　30.4 Traps

31. Gastric Pull-Up
　31.1 History
　31.2 Indications
　31.3 Contraindications
　31.4 Preoperative Preparation
　31.5 Operative Steps
　31.6 Complications

32. Early Primary Tumor with Advanced Neck Disease
　32.1 Introduction
　32.2 Case Example
　32.3 Presentation Evaluation
　32.4 Treatment Options
　32.5 Surgery Followed by Directed Adjuvant Therapy
　32.6 Concurrent Chemoradiaiton
　32.7 Chemoselection
　32.8 Salvage Neck Dissection
　32.9 Case Conclusion

33. Targeted Therapy for the Treatment of Advanced Squamous Cell Carcinoma of the Larynx
　33.1 Introduction
　33.2 Case Discussion
　33.3 Targeting the Epidermal Growth Factor Receptor in the First-line Setting
　33.4 Case Discussion (Continued)
　33.5 Targeted Therapy after Failure of Platinum-Based Chemotherapy
　33.6 Predictive Biomarkers
　33.7 Future Directions

34. Laryngeal Transplantation
　34.1 Case Report
　34.2 Discussion
　34.3 Tips
　34.4 Traps