Spermatogenesis: Biology and Clinical Implications

Senior investigators internationally have here collaborated to produce an international reference work.
Each contributor provides critical and thought provoking concepts and ideas based on the latest
developments in their field. The result is a must read and timely reference work for investigators who are
interested in how spermatogenesis is currently understood and which are the most promising avenues
for future research; an Introduction sets the context for the chapter and points out the relevance of the
research for basic research scientists and clinicians.




1. Golgi apparatus regulation of differentiation: A case study for male germ cells of the rat testis
　　Louis Hermo, Regiana L. Oliveira, Charles E. Smith, Catherine E. Au, and John J. M. Bergeron

2. Androgen regulation of spermatogenesis
　　William H. Walker

3. Testicular immunoregulation: The role of Tyro3, Axl, and Mer receptor tyrosine kinases and
　 pattern recognition receptors
　　Fei Wang, Qian Jiang, and Daishu Han

4. Inflammation and Spermatogenesis
　　Maria Susana Theas, Patricia VerŦnica Jacobo, Cecilia Valeria PIJrez, Vanesa Anabella Guazzone,
　　and Livia Lustig

5. Junctional adhesion molecule (JAM) family: Recent findings and their role and regulation
　 in spermatogenesis
　　Kun Huang and Wing-Yee Lui

6. Sertoli cell immune regulation within the testis
　　Gurvinder Kaur, Kandis Wright, Robin Hannah Greer, Karl Mueller, Allan Haynes, and Jannette M. Dufour

7. The mitotic phase of spermatogenesis: Recent advances and perspectives
　　Kin Lam Fok and Hsiao Chang Chan

8. Genetics of mammalian meiosis
　　Fang Yang and P. Jeremy Wang

9. Roles of membrane and nuclear estrogen receptors in spermatogenesis
　　Paul S. Cooke, Manjunatha K. Nanjappa, Sergei G. Tevosian, and Rex A. Hess

10. Regulation of fertility and infertility in humans
　　Nahid Punjani, Ryan Flannigan, and Peter N. Schlegel

11. Male infertility: Evaluation and treatment
　　Ryan Flannigan and Marc Goldstein

12. Effects of chemical pollutants on spermatogenesis and implications in male infertility
　　Chris KC Wong

13. Advances in our understanding of human spermatogenesis
　　Qing Wen, Elizabeth I. Tang, Tito Jesus, Bruno Silvestrini, and C. Yan Cheng

14. A look into the testis as a reservoir for HIV and ZIKV―A reproductive biologist’s perspective
　　Elizabeth I. Tang, Christopher L. Robinson, Chi Nok Chong, Shuibing Chen, and C. Yan Cheng

15. Cytoskeletons (F-actin) and spermatogenesis
　　Liza O’Donnell and Peter G. Stanton

16. Roles of mTOR signaling in spermatogenesis
　　Lan Ye and Ke Zheng

17. Does planar cell polarity matter during spermatogenesis?
　　Linxi Li, Haiqi Chen, Qingquan Lian, Ren-Shan Ge, and C. Yan Cheng

18. Computational characterization and integrative analysis of proteins involved in Spermatogenesis
　　Pranitha Jenardhanan, Manivel Panneerselvam, and Premendu P. Mathur

19. Effects of chemical exposures on testis cell-cell interactions and endocrine function
　　Rachel C. Knight, Jennifer R. Panizzi, and Benson T. Akingbemi

20. Environmental toxicants on Leydig cell function
　　Leping Ye, Xiaoheng Li, Xiaomin Chen, Qingquan Lian, and Ren-Shan Ge