This book provides a comprehensive overview of how to use MRI for the imaging of lung disease. Special emphasis
is placed on routine applications and the clinical impact of MRI in each setting. In addition, current technological
developments are reviewed and information presented on dedicated applications of MRI in preclinical and
translational research, clinical trials, and specialized institutions.
During the past two decades, significant advances in the technology have enabled MRI to enter and mature in the
clinical arena of chest imaging. Standard protocols are now readily available on MR scanners, and MRI is
recommended as the first- or second-line imaging modality for a variety of lung diseases, not limited to cystic
fibrosis, pulmonary hypertension, and lung cancer. The benefits and added value of MRI originate from its ability to
both visualize lung structure and provide information on different aspects of lung function, such as perfusion,
respiratory motion, ventilation, and gas exchange. On this basis, novel quantitative surrogates for lung function and
therapy control (imaging biomarkers) are generated.
The second edition of MRI of the Lung has been fully updated to take account of recent advances. It is written by an
internationally balanced team of renowned authors representing all major groups in the field.
Technical
1. General Requirements of MRI of the Lung and Suggested Standard Protocol
2. MR Angiography of the Pulmonary Vasculature
3. MR Perfusion in the Lung
4. MRI of Pulmonary Ventilation
4.1 Hyperpolarised He MRI: Physical Methods for Imaging Human Lung Function
4.2 Hyperpolarized Xenon MRI of the Lung
4.3 Fluorine MRI
4.4 Proton MRI: Oxygen-enhanced Lung MRI and Alternative Approaches
5. Respiratory Mechanics and Pulmonary Motion
Clinical
6. Pulmonary Hypertension and Thromboembolic Disease
7. Vascular Anomalies and Diseases
8. Asthma
9. Chronic Obstructive Pulmonary Diseases
10. Cystic Fibrosis
11. Lung Cancer
12. Mediastinal Disease
13. Pulmonary Infections - Pneumonia
14. Interstitial Lung Disease
15. Diseases of the Pleura and the Chest Wall