Gout and Other Crystal Arthropathies - Expert Consult: Online and Print

Gout and Other Crystal Arthropathies, by Dr. Robert Terkeltaub, presents the state-of-the-art, clinically-focused
coverage you need to manage these increasingly prevalent diseases. Diagnose the full range of crystal arthropathies-
including pseudogout, intercritical gout, hyperuricemia, and gouty arthritis-and treat your patients effectively with
discussions of recently-approved drugs like Uloric and those currently under review, such as Kristexxa and Colcryst.
With coverage of the latest therapies, preventions, and imaging studies, along with access to the fully searchable text
online at www.expertconsult.com, this comprehensive resource is ideal for any physician who diagnoses, treats, and
manages gout and crystal-induced arthropathies.

Key Features
뷒ccess the fully searchable contents online at www.expertconsult.com.


뷨tay current on recent developments such as uricosuric therapy and inhibitor therapy; gout flare prophylaxis and
colchicines; ultrasound in the diagnosis of crystal deposition diseases; imaging of gout, CPPD, and hydroxyapatitie
deposition diseases; and uricase therapy of gout.



뷢anage the full range of crystal arthropathies with 25 clinically-focused chapters on pseudogout, intercritical gout,
hyperuricemia, gouty arthritis, and more.



뷪reat your patients effectively using the latest information on drug treatments, from the recently-approved Uloric to
Kristexx and Colcryst, which are still under review.


Author Information
By Robert Terkeltaub, VA Rheumatology Section Chief, San Diego Professor of Medicine, University of California San
Diego

Table of Contents
I

Foreword


II

Introduction


1

Pathology of Crystal Deposition Diseases


2

Synovial Fluid Crystal Analysis


3

Purine Metabolism in the Pathogenesis of Hyperuricemia, and Inborn Errors of Purine Metabolism Associated with Disease


4

Renal Basis of Hyperuricemia


5

Pathogenesis of Tophus Formation and Gouty Inflammation


6

Gout: Epidemiology and Risk Factors


7

Genetics of Gout


8

Diagnosis of Gout


9

Clinical Features of Gout


10

Treatment of Acute Gout


11

Diet, Alcohol, Obesity, and Hyperuricemia


12

Uricosuric Therapy of Hyperuricemia in Gout


13

Xanthine Oxidase Inhibitor Treatment of Hyperuricemia


14

Uricase Therapy of Gout


15

Prophylaxis of Attacks of Acute Gouty Arthritis


16

Overview of Gout Therapy Strategy and Targets and Management of Refractory Disease


17

Quality of Care in Gout


18

Health-Related Quality of Life and Outcome Measures in Gout


19

Asymptomatic Hyperuricemia: Cardiovascular and renal Implications


20

Pathogenesis and Molecular Genetics of Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

21

Clinical Features, Diagnosis, and Treatment of CPPD Crystal Arthropathy


22

Basic Calcium Phosphate Crystal Arthropathy


23

Crystalline Disorders Associated with Renal Disease Including Oxalate Arthropathy


24

Plain Radiography and Advanced Imaging of Gout


25

Plain Radiography and Advanced Imaging of CPPD and Hydroxyapatite Deposition Diseases


26

Ultrasound in the Diagnosis of Crystal Deposition Disease


27

Developing the future of diagnosis and management of gout and other crystal deposition arthropathies