Hematopathology 2/e

The world's leading reference in hematopathology returns with this completely updated second edition. Authored by
international experts in the field, it covers a broad range of hematologic disorders -- both benign and malignant --
with information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. Comprehensive in
scope, it's a must-have resource for both residents and practicing pathologists alike.
Authored by the chief architects of the WHO classification in neoplasms of hematopoietic and lymphoid tissue.
Covers the newest diagnostic techniques, including molecular, immunohistochemical, and genetic studies.
Confirm or challenge your diagnostic interpretations by comparing specimens to over 1,000 high-quality color images.
Boasts detailed, practical advice from world leaders in hematopathology.
Places an emphasis on pathologic diagnoses, including molecular and genetic testing.
Updated with the most current WHO classifications of hematologic disease, including lymphoma and leukemia and
peripheral T-cell lymphomas.
Covers hot topics in hematopathology, such as the latest genetic insights into lymphoma and leukemia; the new
nomenclature for myelodysplastic syndromes; new developments on the subject of Grey zone lymphoma; and much more.
Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the
text, figures, images, and references from the book on a variety of devices. There's also a downloadable image bank,
and Virtual Microscope Slides are featured in several chapters.

Give your clinicians the best guidance with this comprehensive reference in hematopathology.

Contents


Part I: TECHNICAL ASPECTS

1. Processing of the Lymph Node Biopsy Specimen 　　


2. Fine Needle Aspiration of Lymph Nodes 　　


3. Collection, Processing, and Examination of Bone Marrow Specimens


4. Immunohistochemistry for the Hematopathology Laboratory

　　

5. Flow Cytometry

　　

6. Molecular Diagnosis in Hematopathology

　　

7. Important Chromosomal Aberrations in Hematologic Neoplasms and Key Techniques to Diagnose Them　　


Part II: NORMAL and REACTIVE CONDTIONS of HEMATOPOIETIC TISSUES

8. Normal Lymphoid Organs and Tissues

　　

9. The Reactive Lymphadenopathies


10. The Normal Bone Marrow

　　

11. Evaluation of Anemia, Leukopenia, and Thrombocytopenia

　　

12. Bone Marrow Findings in Inflammatory, Infectious, and Metabolic Disorders


Part III: LYMPHOID NEOPLASMS

13. Principles of Classification of Lymphoid Neoplasms

　　

Section 1: Mature B-Cell Neoplasms

14. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and B-Cell Prolymphocytic Leukemia

　　

15. Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia

　　

16. Hairy Cell Leukemia

　　

17. Splenic Marginal Zone Lymphoma and Other Small B-Cell Neoplasms in the Spleen

　　

18. Follicular Lymphoma

　　

19. Extranodal Marginal Zone Lymphoma: MALT Lymphoma

　　

20. Primary Cutaneous B-Cell Lymphomas

　　

21. Nodal Marginal Zone Lymphoma

　　

22. Mantle Cell Lymphoma

　　

23. Diffuse Large B-Cell Lymphoma


24. Burkitt Lymphoma and its Mimics


25. Plasmablastic Neoplasms Other Than Plasma Cell Myeloma


26. Plasma Cell Neoplasms

　　

27. Nodular Lymphocyte-Predominant Hodgkin's Lymphoma

　　

28. Classical Hodgkin's Lymphoma and Related Lesions


29. Virally Associated B-Cell Lymphoproliferative Disease

　　

Section 2: MATURE T-CELL AND NK-CELL NEOPLASMS


30. Virally Associated T-Cell and NK-Cell Neoplasms

　　

31. T-Cell and NK-Cell Large Granular Lymphocyte Proliferations

　　

32. T-Cell Prolymphocytic Leukemia


33. Adult T-Cell Leukemia/Lymphoma

　　

34. Hepatosplenic T-Cell Lymphoma

　　

35. Peripheral T-Cell Lymphoma, Not Otherwise Specified

　　

36. Angioimmunoblastic T-Cell Lymphoma

　　

37. Anaplastic Large-Cell Lymphoma, ALK Positive and ALK Negative

　　

38. Enteropathy-Associated T-Cell Lymphoma and Other Primary Intestinal T-Cell Lymphomas

　　
39. Mycosis Fungoides and Sézary Syndrome

　　

40. Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders

　　

41. Primary Cutaneous T-Cell Lymphomas: Rare Subtypes

　　

Section 3: Precursor B- and T-Cell Neoplasms


42. Precursor B- and T-Cell Neoplasms

　　

43. Acute Leukemias of Ambiguous Lineage


Part IV: MYELOID NEOPLASMS

44. Principles of Classification of Myeloid Neoplasms

　　

45. The Myelodysplastic Syndromes

　　

46. Acute Myeloid Leukemia


47. Myeloproliferative Neoplasms

　　

48. Myelodysplastic/Myeloproliferative Neoplasms

　　

49. Mastocytosis

　　

50. Eosinophilia and Chronic Eosinophilic Leukemia, Including Myeloid/Lymphoid Neoplasms with Eosinophilia and
Rearrangement of PDGFRA, PDGFRB, FGFR1, or JAK2

　　

51. Blastic Plasmacytoid Dendritic Cell Neoplasm

　　

Part V: HISTIOCYTIC PROLIFERATIONS

52. Nonneoplastic Histiocytic Proliferations of Lymph Nodes and Bone Marrow

　　

53. Histiocytic and Dendritic Cell Neoplasms Including Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma

　　

Part VI: IMMUNODEFICIENCY DISORDERS

54. The Pathology of Primary Immunodeficiencies

　　

55. Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorder

　　

Part VII: SITE-SPECIFIC ISSUES in the DIAGNOSIS of LYMPHOMA and LEUKEMIA

56. Bone Marrow Evaluation for Lymphoma


57. Evaluation of the Bone Marrow After Therapy


58. Non-Hematopoietic Neoplasms of the Bone Marrow

　　

59. Nonlymphoid Lesions of the Lymph Nodes

　　

60. Spleen: Normal Architecture and Neoplastic and Nonneoplastic Lesions

　　

61. Diagnosis of Lymphoma in Extranodal Sites Other Than Skin