Comprehensive Management of Arteriovenous Malformations of the Brain and Spine

Vascular malformations of the brain and spine pose many management challenges. This text provides a comprehensive,
state-of-the-art review of the natural history, treatment options, and outcomes of patients with these conditions.
Despite their relative rarity, these lesions are responsible for devastating injury to individuals and can cause an
enduring physical, psychological, and economic burden on patients and families. Many new therapeutic options are now
available with the advent of novel surgical, endovascular, and radiosurgical techniques. The basic sciences have
fuelled development of small molecule and biologic therapies targeting the molecular basis of disease. Authored by
international experts in the fields of neurosurgery, neurology, radiology, and radiation oncology, this book provides
state-of-the-art treatment plans and discussions of ideal therapy. This text is aimed at practitioners in the fields of
neurology, neurosurgery, neuroradiology, radiation oncology, rehabilitation medicine and allied fields who care for
patients with brain and spinal vascular malformations.

Talbe of Contents

Preface
Part I. Development, Anatomy, and Physiology of Arteriovenous Malformations of the Central Nervous System:
1. Development of the central nervous system vasculature and the pathogenesis of brain arteriovenous malformations
2. Cranial vascular anatomy and implications for arteriovenous malformation and dural arteriovenous fistula treatment
3. Spinal vascular anatomy and implications for treatment of arteriovenous malformations
4. Physiology and hemodynamics of arteriovenous malformations
5. Natural history of arteriovenous malformations and indications for treatment
Part II. Evaluation and Treatment Considerations for Arteriovenous Malformations:
6. Imaging evaluation of arteriovenous malformations
7. Intraoperative evaluation of blood flow with indocyanine green videoangiography
8. Neuromonitoring for arteriovenous malformation surgery
9. Neuroanesthesia for treatment of arteriovenous malformations
10. Classification of brain and spinal arteriovenous malformations and arteriovenous fistulas
Part III. Surgical Approaches to the Treatment of Arteriovenous Malformations:
11. Surgical approaches and nuances for supratentorial arteriovenous malformations
12. Surgical approaches and nuances for arteriovenous malformations in the posterior fossa
13. Surgical management of cerebral dural arteriovenous fistulas
14. Surgery of spinal arteriovenous malformations and arteriovenous fistulas
15. Surgery of basal ganglia, thalamic, and brainstem arteriovenous malformations
Part IV. Medical, Endovascular, and Radiosurgical Treatment of Arteriovenous Malformations:
16. Complications of arteriovenous malformation rupture and medical management of hemorrhage
17. Endovascular treatment of supratentorial arteriovenous malformations
18. Endovascular treatment of arteriovenous malformations of the posterior fossa
19. Endovascular treatment of arteriovenous fistulas of the brain
20. Endovascular management of vein of Galen malformations
21. Endovascular treatment of spinal arteriovenous malformations and arteriovenous fistulas
22. Radiosurgical basics for the treatment of arteriovenous malformations: indications and techniques
23. Radiosurgery for brain arteriovenous malformations and arteriovenous fistulas
24. Radiosurgery for spinal arteriovenous malformations and arteriovenous fistulas
25. Multidisciplinary treatment of arteriovenous malformations
26. Palliative treatment of inoperable arteriovenous malformations
27. Pediatric arteriovenous malformations: special considerations
28. Management of residual or recurrent arteriovenous malformations
Index.