Williams Textbook of Endocrinology 13/e

For more than 65 years, Williams Textbook of Endocrinology has been the gold standard in the field, delivering
authoritative guidance on every aspect of adult and pediatric endocrine system disorders. The 13th Edition has been
thoroughly updated by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg, to bring you
state-of-the-art coverage of diabetes, metabolic syndrome, obesity, thyroid disease, testicular disorders, and much
more, all designed to help you provide optimal care to every patient. Bridging the gap between basic science and
clinical information, it is an essential, relevant resource for endocrinologists, endocrine surgeons, gynecologists,
internists, and pediatricians - any clinician who needs the most reliable coverage available on the diverse features
across the spectrum of endocrine disease.
Obtain a better understanding of both scientific insight and clinical data from the classic reference that delivers
the current information you need in a highly illustrated, user-friendly format.
Stay up to date with expanded discussions of autoimmune thyroid diseases, mechanisms, and the appropriate treatment of
the ophthalmopathy of Graves’ disease; a new section on the interpretation of fine needle aspiration results in
patients with thyroid nodules; and new coverage of when and when not to use radioiodine in the treatment of patients
with thyroid cancer.

Update your knowledge and skills with all-new chapters on Genetics of Endocrine Disease, Endocrinology of Population
Health, and Laboratory Techniques for Recognition of Endocrine Disorders.

Confidently manage any clinical endocrinopathy you may encounter thanks to new information on recent FDA-approved
drugs for pituitary disorders, a new focus on pediatrics, and new content on diabetes, obesity, and appetite control.

Benefit from the expertise of dynamic new contributors who offer fresh perspectives throughout.


table of contents
Section I: Hormones and Hormone Action

1. Principles of Endocrinology

2. Clinical Endocrinology: A Personal View

3. Principles of Hormone Action

4. Genetics of Endocrine Disease

5. Endocrinology of Population Health

6. Laboratory Techniques for Recognition of Endocrine Disorders


Section II: Hypothalamus and Pituitary

7. Neuroendocrinology

8. Pituitary Physiology and Diagnostic Evaluation

9. Pituitary Masses and Tumors

10. Posterior Pituitary


Section III: Thyroid

11. Thyroid Pathophysiology and Diagnostic Evaluation

12. Hyperthyroid Disorders

13. Hypothyroidism and Thyroiditis

14. Nontoxic Diffuse and Nodular Goiter and Thyroid Neoplasia


Section IV: Adrenal Cortex and Endocrine Hypertension

15. The Adrenal Cortex

16. Endocrine Hypertension


Section V: Reproduction

17. Physiology and Pathology of the Female Reproductive Axis

18. Hormonal Contraception

19. Testicular Disorders

20. Sexual Dysfunction in Men and Women


Section VI: Endocrinology and the Life Span



Section VI A: Maternal Fetal

21. Endocrine Changes in Pregnancy

22. Endocrinology of Fetal Development


Section VI B: Childhood

23. Pediatric Disorders of Sex Development

24. Normal and Aberrant Growth in Children

25. Physiology and Disorders of Puberty


Section VI C: Adult

26. Hormones and Athletic Performance

27. Endocrinology and Aging


Section VII: Mineral Metabolism

28. Hormones and Disorders of Mineral Metabolism

29. Osteoporosis and Other Metabolic Bone Diseases

30. Kidney Stones


Section VIII: Carbohydrates and Fat Metabolism

31. Type 2 Diabetes Mellitus

32. Type 1 Diabetes Mellitus

33. Complications of Diabetes Mellitus

34. Hypoglycemia

35. Neuroendocrine Control of Energy Stores

36. Obesity

37. Disorders of Lipid Metabolism

38. Gastrointestinal Hormones and Gut Endocrine Tumors


Section IX: Polyendocrine and Neoplastic Disorders

39. Multiple Endocrine Neoplasia

40. The Immunoendocrinopathy Syndromes

41. Endocrinology of HIV/AIDS

42. Endocrine Management of the Cancer Survivor

43. Neuroendocrine Tumors