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Section I: Introduction to Molecular Medicine
1. Molecular Basis of Human Disease
Ivor J. Benjamin
Section II: Cardiovascular Disease
2. Structure and Function of the Normal Heart and Blood Vessels
Nicole Lohr and Ivor J. Benjamin
3. Evaluation of the Patient with Cardiovascular Disease
James Kleczka and Ivor J. Benjamin
4. Diagnostic Tests and Procedures in the Patient with Cardiovascular Disease
Ivor J. Benjamin and James Macioch
5. Heart Failure and Cardiomyopathy
Claudius Mahr, Nunzio Gaglianello and Ivor J. Benjamin
6. Congenital Heart Disease
Michael G. Earing
7. Acquired Valvular Heart Disease
Timothy Woods
8. Coronary Heart Disease
Michael P. Cinquegrani
9. Cardiac Arrhythmias
James A. Roth, Marci Berger and Jason C. Rubenstein
10. Pericardial and Myocardial Disease
Jennifer L. Strande, Panayotis Fasseas and Ivor J. Benjamin
11. Other Cardiac Topics
Robert Love, Mohamed F. Algahim and Ivor J. Benjamin
12. Vascular Diseases and Hypertension
Ronald G. Victor and Wanpen Vongpatanasin
Section III: Pulmonary and Critical Care Medicine
13. The Lung in Health and Disease
Sharon Rounds and Matthew Jankowich
14. General Approach to Patients with Respiratory Disorders
Brian Casserly and Sharon Rounds
15. Evaluating Lung Structure and Function
Jigme Sethi and F. Dennis McCool
16. Obstructive Lung Diseases
Matthew Jankowich
17. Interstitial Lung Diseases
Jason M. Aliotta and Matthew Jankowich
18. Pulmonary Vascular Disease
Sharon Rounds and Matthew Jankowich
19. Disorders of Respiratory Control
Sharon Rounds and Matthew Jankowich
20. Disorders of the Pleura, Mediastinum, and Chest Wall
Eric Gartman and F. Dennis McCool
21. Infectious Diseases of the Lung
Brian Casserly and Sharon Rounds
22. Essentials In Critical Care Medicine
Brian Casserly and Sharon Rounds
23. Neoplastic Disorders of the Lung
Jason M. Aliotta
Section IV: Preoperative and Postoperative Care
24. Preoperative and Postoperative Care
Prashant Vaishnava and Kim Eagle
Section V: Renal Disease
25. Elements of Renal Structure and Function
Orson W. Moe and Biff F. Palmer
26. Approach to the Patient with Renal Disease
Rajiv Agarwal and Biff F. Palmer
27. Fluid and Electrolyte Disorders
Biff F. Palmer
28. Glomerular Diseases
Fernando Fervenza and Biff F. Palmer
29. Major Nonglomerular Disorders
Ramesh Saxena and Biff F. Palmer
30. Vascular Disorders of the Kidney
Jeffrey S. Berns and Biff F. Palmer
31. Acute Kidney Injury
Mark A. Perazella, Jeffrey Turner and Biff F. Palmer
32. Chronic Renal Failure
Kerri L. Cavanaugh, T. Alp Ikizler and Biff F. Palmer
Section VI: Gastrointestinal Disease
33. Common Clinical Manifestations of Gastrointestinal Disease
Michael Wolfe
A. Abdominal Pain
Charles M. Bliss Jr. and Michael Wolfe
B. Gastrointestinal Hemorrhage
D. Roy Ferguson and Michael Wolfe
C. Malabsorption
Elihu Schimmel, Sharmeel Wasan and Michael Wolfe
D. Diarrhea
John S. Maxwell and Michael Wolfe
34. Endoscopic and Imaging Procedures
Christopher S. Huang and Michael Wolfe
35. Esophageal Disorders
Carla Maradey-Romero, Ronnie Fass and Michael Wolfe
36. Diseases of the Stomach and Duodenum
Robert C. Lowe and Michael Wolfe
37. Inflammatory Bowel Disease
Hannah Miller, Francis A. Farraye and Michael Wolfe
38. Diseases of the Pancreas
David Lichtenstein and Michael Wolfe
Section VII: Diseases of the Liver and Biliary System
39. Laboratory Tests in Liver Disease
Shaheryar A. Siddiqui and Michael B. Fallon
40. Jaundice
Klaus E. Mönkemüller, Helmut Neumann and Michael B. Fallon
41. Acute and Chronic Hepatitis
Jenjung Pan and Michael B. Fallon
42. Acute Liver Failure
Brendan Martin McGuire and Michael B. Fallon
43. Cirrhosis of the Liver and its Complications
Shaheryar A. Siddiqui and Michael B. Fallon
44. Disorders of the Gallbladder and Biliary Tract
Matthew P. Spinn and Michael B. Fallon
Section VIII: Hematologic Disease
45. Hematopoiesis and Hematopoietic Failure
Eunice S. Wang and Nancy Berliner
46. Clonal Disorders of the Hematopoietic Stem Cell
Eunice S. Wang and Nancy Berliner
47. Disorders of Red Blood Cells
Michal G. Rose and Nancy Berliner
48. Clinical Disorders of Neutrophils
Michal G. Rose and Nancy Berliner
49. Disorders of Lymphocytes
Jill Lacy and Stuart Seropian
50. Normal Hemostasis
Christine S. Rinder and Henry M. Rinder
51. Disorders of Hemostasis: Bleeding
Christopher Anthony Tormey and Henry M. Rinder
52. Disorders of Hemostasis: Thrombosis 580
Richard Torres and Henry M. Rinder
Section IX: Oncologic Disease
53. Cancer Biology and Etiologic Factors
Aram Hezel and Alok Khorana
54. Cancer Epidemiology and Cancer Prevention
Gary H. Lyman, Nicole Kuderer and Alok Khorana
55. Principles of Cancer Therapy
Davendra Sohal and Alok Khorana
56. Lung Cancer
Patrick C. Ma and Alok Khorana
57. Gastrointestinal Cancers
Davendra Sohal and Alok Khorana
58. Genitourinary Cancers
Jorge A. Garcia, Brian Rini, Timothy D. Gilligan, Robert Dreicer and Alok Khorana
59. Breast Cancer
Gary H. Lyman, Nicole Kuderer and Alok Khorana
60. Other Solid Tumors: Head/Neck, Sarcomas, Melanoma, Unknown Primary
Michael McNamara and Alok Khorana
61. Complications of Cancer and Cancer Treatment
Bassam Estfan and Alok Khorana
Section X: Endocrine Disease & Metabolic Disease
62. Hypothalamic-Pituitary Axis
Kawaljeet Kaur and Diana Maas
63. Thyroid Gland
Theodore C. Friedman
64. Adrenal Gland
Theodore C. Friedman
65. Male Reproductive Endocrinology
Glenn D. Braunstein
66. Diabetes Mellitus, Hypoglycemia
Robert J. Smith
67. Obesity and Eating Disorders
Osama Hamdy and Robert J. Smith
68. Malnutrition, Nutritional Assessment, and Nutritional Support in Adult Patients
Thomas Ziegler
69. Disorders of Lipid Metabolism
Geetha Gopalakrishnan and Robert J. Smith
Section XI: Women's Health
70. Women’s Health Topics
Kelly McGarry, Kimberly Babb, Laura Edmonds, Christine Duffy, Michelle Anvar and Jennifer Jeremiah
Section XII: Men's Health
71. Men's Health Topics
Joseph A. Smith Jr. and Douglas Milam
Section XIII: Diseases of Bone and Bone Mineral Metabolism
72. Normal Physiology of Bone and Mineral Homeostasis
Andrew F. Stewart
73. Disorders of Serum Minerals
Andrew F. Stewart and Steven Hodak
74. Metabolic Bone Diseases
Andrew F. Stewart and Mara J. Horwitz
75. Osteoporosis
Susan L. Greenspan
Section XIV: Musculoskeletal and Connective Tissue Disease
76. Approach to the Patient with Rheumatic Disease
Niveditha Mohan
77. Rheumatoid Arthritis
Larry W. Moreland
78. Spondyloarthropathies
Douglas W. Lienesch
79. Systemic Lupus Erythematosus
Susan Manzi and Amy H. Kao
80. Scleroderma and Mixed Tissue Diseases
Thomas Medsger and Robyn Domsic
81. Systemic Vasculitis
Kimberly P. Liang
82. Crystal Arthropathies
Ghaith Noaiseh
83. Osteoarthritis
C. Kent Kwoh
84. Nonarticular Soft Tissue Disorders
Niveditha Mohan
85. Rheumatic Manifestations of Systemic Disorders; Sjögren Syndrome
Yong Gil Hwang
Section XV: Infectious Disease
86. Host Defenses Against Infection
Bharat Ramratnam
87. Laboratory Diagnosis of Infectious Diseases
Kimberle Chapin
88. Fever and Febrile Syndromes
Ekta Gupta and Maria Denise Mileno
89. Bacteremia and Sepsis Syndrome
Steven M. Opal and Russell McCulloh
90. Infections of the Nervous System
Avindra Nath and Allan Tunkel
91. Infections of the Head and Neck
Edward Wing
92. Infections of the Lower Respiratory Tract
John R. Lonks
93. Infections of the Heart and Blood Vessels
Eleftherios E. Mylonakis and Cheston B. Cunha
94. Skin and Soft Tissue Infections
Sajeev Handa
95. Intra-Abdominal Abscess and Peritonitis
Edward Wing
96. Infectious Diarrhea
Awewura Kwara
97. Infections Involving Bones and Joints
Jerome Larkin
98. Infections of the Urinary Tract
Joao M. Travares and Steven M. Opal
99. Health Care-Associated Infections
S Shaefer Spires and Tom Talbot
100. Sexually Transmitted Infections
Philip A. Chan
101. Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome
Brian Tucker Montague, Aadia Rana and Timothy Flanigan
102. Infections in the Immunocompromised Host
Staci Fischer
103. Infectious Diseases of Travelers: Protozoal and Helminthic Infections
Erna Milunka Kojic
Section XVI: Neurologic Disease
104. Neurologic Evaluation of the Patient
Frederick J. Marshall
105. Disorders of Consciousness
Mohamad Chmayssani and Paul Vespa
106. Disorders of Sleep
Selim R. Benbadis
107. Cortical Syndromes
Sinead M. Murphy and Timothy Counihan
108. Dementia and Memory Disturbances
Frederick J. Marshall
109. Major Disorders of Mood, Thoughts, and Behavior
Jeffrey M. Lyness
110. Autonomic Nervous System Disorders
William P. Cheshire Jr.
111. Headache, Neck and Back Pain and Cranial Neuralgias
Timothy Counihan
112. Disorders of Vision and Hearing
Timothy Counihan
113. Dizziness and Vertigo
Kevin A. Kerber
114. Disorders of the Motor System
Kevin Michael Biglan
115. Developmental and Neurocutaneous Disorders
Maxwell H. Sims and Jennifer M. Kwon
116. Cerebrovascular Disease
Mitchell Elkind
117. Traumatic Brain Injury and Spinal Cord Injury
Geoff Ling
118. Epilepsy
Michel Berg
119. Central Nervous System Tumors
Lisa Rogers
120. Demyelinating and Inflammatory Disorders
Anne Haney Cross
121. Neuromuscular Diseases: Disorders of the Motor Neuron and Plexus and Peripheral Nerve Disease
Carlayne E. Jackson
122. Muscle Diseases
Robert C. Griggs and Jeffrey M. Statland
123. Neuromuscular Junction Disease
Emma Ciafaloni
Section XVII: Geriatrics
124. The Aging Patient
Harvey Jay Cohen and Mitchell Heflin
Section XVIII: Palliative Care
125. Palliative Care
Robert G. Holloway and Timothy Quill
Section XIX: Alcohol and Substance Abuse
126. Alcohol and Substance Abuse
Richard A. Lange and L. David Hillis