Transplantation at a Glance

Transplantation at a Glance


The first basic overview of all aspects of transplantation with a clarity not to be found in more inaccessible
textbooks.




This brand new title provides a succinct overview of both the scientific and clinical principles of organ
transplantation and the types of organ transplant, featuring highly-illustrated information covering core topics in
transplantation including:
- Organ donors
- Organ preservation
- Assessment of transplant recipients
- Indications for transplantation
- Immunology of transplantation
- Immunosuppression and its complications
- Overviews of thoracic and abdominal organ transplantation, including the kidneys, liver, heart and lungs




Transplantation at a Glance is the ideal introduction for medical students, junior doctors, surgical trainees,
immunology students, pharmacists, and nurses on transplant wards.


Table of Contents




1 History of transplantation 10




Organ donors




2 Diagnosis of death and its physiology 12




3 Deceased organ donation 14




4 Live donor kidney transplantation 16




5 Live donor liver transplantation 18




Organ preservation




6 Organ preservation 20




Immunology of organ transplantation




7 Innate immunity 22




8 Adaptive immunity and antigen presentation 24




9 Humoral and cellular immunity 26




Histocompatibility in transplantation




10 Tissue typing and HLA matching 28




11 Detecting HLA antibodies 30




12 Antibody-incompatible transplantation 32




Organ allocation




13 Organ allocation 34




Immunosuppression




14 Immunosuppression: induction vs maintenance 36




15 Biological agents 37




16 T cell-targeted immunosuppression 38




Complications of immunosuppression




17 Side effects of immunosuppressive agents 40




18 Post-transplant infection 42




19 CMV infection 44




20 Post-transplant malignancy 46




Kidney transplantation




21 End-stage renal failure 48




22 Complications of ESRF 50




23 Dialysis and its complications 52




24 Assessment for kidney transplantion 54




25 Kidney transplantation: the operation 56




26 Surgical complications of kidney transplantation 58




27 Delayed graft function 60




28 Transplant rejection 62




29 Chronic renal allograft dysfunction 64




Pancreas and islet transplantation




30 Transplantation for diabetes mellitus 66




31 Pancreas transplantation 68




32 Islet transplantation 70




Liver transplantation




33 Causes of liver failure 72




34 Assessment for liver transplantation 74




35 Liver transplantation: the operation 76




36 Complications of liver transplantation 78




Intestinal transplantation




37 Intestinal failure and assessment 80




38 Intestinal transplantation 82




Heart transplantation




39 Assessment for heart transplantation 84




40 Heart transplantation: the operation 86




41 Complications of heart transplantation 88




Lung transplantation




42 Assessment for lung transplantation 90




43 Lung transplantation: the operation 92




44 Complications of lung transplantation 94




Composite tissue transplantation




45 Composite tissue transplantation 96




Xenotransplantation




46 Xenotransplantation 98




Index 100