DeVita Hellman and Rosenberg s Cancer: Principles and Practice of Oncology 10/e

(Cancer: Principles & Practice (DeVita)(Single Vol.))

DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology has garnered universal acclaim as the
world's definitive, standard-setting oncology reference. More than 400 respected luminaries explore today's most
effective strategies for managing every type of cancer by stage of presentation - discussing the role of all
appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help
your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every
cancer patient.

Features

Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking
developments in cancer care.
Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer,
Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive
updates throughout ?including coverage of the newest biologic therapies.
Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon,
a medical oncologist, and a radiation oncologist in each major treatment chapter.
Review the latest molecular biology knowledge for each type of cancer and its implications for improved management.
Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life
issues.
Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access
to:

Complete content with enhanced navigation
A powerful search that pulls results from content in the book, your notes, and even the web
Cross-linked pages, references, and more for easy navigation
Highlighting tool for easier reference of key content throughout the text
Ability to take and share notes with friends and colleagues
Quick reference tabbing to save your favorite content for future use



Table of Contents

Chapter 1: The Cancer Genome




Chapter 2: Hallmarks of Cancer: An Organizing Principle for Cancer Medicine




Chapter 3: Molecular Methods in Cancer




Chapter 4: Tobacco




Chapter 5: Oncogenic Viruses




Chapter 6: Inflammation




Chapter 7: Chemical Factors




Chapter 8: Physical Factors




Chapter 9: Dietary Factors




Chapter 10: Obesity and Physical Activity




Chapter 11: Epidemiologic Methods




Chapter 12: Trends in United States Cancer Mortality




Chapter 13: Essentials of Radiation Therapy




Chapter 14: Cancer Immunotherapy




Chapter 15: Pharmacokinetics and Pharmacodynamics of Anticancer Drugs




Chapter 16: Pharmacogenomics




Chapter 17: Alkylating Agents




Chapter 18: Platinum Analogs




Chapter 19: Antimetabolites




Chapter 20: Topoisomerase Interactive Agents




Chapter 21: Antimicrotubule Agents




Chapter 22: Kinase Inhibitors as Anticancer Drugs




Chapter 23: Histone Deacetylase Inhibitors and Demethylating Agents




Chapter 24: Proteasome Inhibitors




Chapter 25: Poly (ADP-ribose) Polymerase Inhibitors




Chapter 26: Miscellaneous Chemotherapeutic Agents




Chapter 27: Hormonal Agents




Chapter 28: Antiangiogenesis Agents




Chapter 29: Monoclonal Antibodies




Chapter 30: Assessment of Clinical Response




Chapter 31: Tobacco Use and the Cancer Patient




Chapter 32: Role of Surgery in Cancer Prevention




Chapter 33: Cancer Risk Reducing Agents




Chapter 34: Cancer Screening




Chapter 35: Genetic Counseling




Chapter 36: Design and Analysis of Clinical Trials




Chapter 37: Molecular Biology of Head and Neck Cancers




Chapter 38: Cancer of the Head and Neck




Chapter 39: Rehabilitation After Treatment of Head and Neck Cancer




Chapter 40: Molecular Biology of Lung Cancer




Chapter 41: Non-Small Cell Lung Cancer




Chapter 42: Small Cell and Neuroendocrine Tumors of the Lung




Chapter 43: Neoplasms of the Mediastinum




Chapter 44: Molecular Biology of the Esophagus and Stomach




Chapter 45: Cancer of the Esophagus




Chapter 46: Cancer of the Stomach




Chapter 47: Genetic Testing in Stomach Cancer




Chapter 48: Molecular Biology of Pancreas Cancer




Chapter 49: Cancer of the Pancreas




Chapter 50: Genetic Testing in Pancreatic Cancer




Chapter 51: Molecular Biology of Liver Cancer




Chapter 52: Cancer of the Liver




Chapter 53: Cancer of the Biliary Tree




Chapter 54: Cancer of the Small Bowel




Chapter 55: Gastrointestinal Stromal Tumor




Chapter 56: Molecular Biology of Colorectal Cancer




Chapter 57: Cancer of the Colon




Chapter 58: Genetic Testing in Colon Cancer (Polyposis Syndromes)




Chapter 59: Genetic Testing in Colon Cancer (Nonpolyposis Syndromes)




Chapter 60: Cancer of the Rectum




Chapter 61: Cancer of the Anal Region




Chapter 62: Molecular Biology of Kidney Cancer




Chapter 63: Cancer of the Kidney




Chapter 64: Molecular Biology of Bladder Cancer




Chapter 65: Cancer of the Bladder, Ureter, and Renal Pelvis




Chapter 66: Genetic Testing in Urinary Tract Cancers




Chapter 67: Molecular Biology of Prostate Cancer




Chapter 68: Cancer of the Prostate




Chapter 69: Cancer of the Urethra and Penis




Chapter 70: Cancer of the Testis




Chapter 71: Molecular Biology of Gynecologic Cancers




Chapter 72: Cancer of the Cervix, Vagina, and Vulva




Chapter 73: Cancer of the Uterine Body




Chapter 74: Genetic Testing in Uterine Cancer




Chapter 75: Gestational Trophoblastic Diseases




Chapter 76: Ovarian Cancer, Fallopian Tube Carcinoma, and Peritoneal Carcinoma




Chapter 77: Genetic Testing in Ovarian Cancer




Chapter 78: Molecular Biology of Breast Cancer




Chapter 79: Malignant Tumors of the Breast




Chapter 80: Genetic Testing in Breast Cancer




Chapter 81: Molecular Biology of Endocrine Tumors




Chapter 82: Thyroid Tumors




Chapter 83: Parathyroid Tumors




Chapter 84: Adrenal Tumors




Chapter 85: Pancreatic Neuroendocrine Tumors




Chapter 86: Carcinoid Tumors and the Carcinoid Syndrome




Chapter 87: Multiple Endocrine Neoplasias




Chapter 88: Genetic Testing in the Endocrine System




Chapter 89: Molecular Biology of Sarcomas




Chapter 90: Soft Tissue Sarcoma




Chapter 91: Sarcomas of Bone




Chapter 92: Cancer of the Skin




Chapter 93: Molecular Biology of Cutaneous Melanoma




Chapter 94: Cutaneous Melanoma

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Chapter 95: Genetic Testing in Skin Cancer




Chapter 96: Molecular Biology of Central Nervous System Tumors




Chapter 97: Neoplasms of the Central Nervous System




Chapter 98: Molecular Biology of Childhood Cancers




Chapter 99: Solid Tumors of Childhood




Chapter 100: Leukemias and Lymphomas of Childhood




Chapter 101: Molecular Biology of Lymphomas




Chapter 102: Hodgkin’s Lymphoma




Chapter 103: Non-Hodgkin’s Lymphoma




Chapter 104: Cutaneous Lymphomas




Chapter 105: Primary Central Nervous System Lymphoma




Chapter 106: Molecular Biology of Acute Leukemias




Chapter 107: Management of Acute Leukemias




Chapter 108: Molecular Biology of Chronic Leukemias




Chapter 109: Chronic Myelogenous Leukemia




Chapter 110: Chronic Lymphocytic Leukemias




Chapter 111: Myelodysplastic Syndromes




Chapter 112: Plasma Cell Neoplasms




Chapter 113: Cancer of Unknown Primary Site




Chapter 114: Benign and Malignant Mesothelioma




Chapter 115: Peritoneal Metastases and Peritoneal Mesothelioma




Chapter 116: Intraocular Melanoma




Chapter 117: HIV-Associated Malignancies




Chapter 118: Transplantation-Related Malignancies




Chapter 119: Superior Vena Cava Syndrome




Chapter 120: Increased Intracranial Pressure




Chapter 121: Spinal Cord Compression




Chapter 122: Metabolic Emergencies




Chapter 123: Metastatic Cancer to the Brain




Chapter 124: Metastatic Cancer to the Lung




Chapter 125: Metastatic Cancer to the Liver




Chapter 126: Metastatic Cancer to the Bone




Chapter 127: Malignant Pleural and Pericardial Effusions




Chapter 128: Malignant Ascites




Chapter 129: Paraneoplastic Syndromes




Chapter 130: Autologous Stem Cell Transplantation




Chapter 131: Allogeneic Stem Cell Transplantation




Chapter 132: Infections in the Cancer Patient




Chapter 133: Neutropenia and Thrombocytopenia




Chapter 134: Cancer Associated Thrombosis




Chapter 135: Nausea and Vomiting




Chapter 136: Diarrhea and Constipation




Chapter 137: Oral Complications




Chapter 138: Pulmonary Toxicity




Chapter 139: Cardiac Toxicity




Chapter 140: Hair Loss




Chapter 141: Gonadal Dysfunction




Chapter 142: Fatigue




Chapter 143: Second Cancers




Chapter 144: Neurocognitive Effects




Chapter 145: Cancer Survivorship




Chapter 146: Management of Cancer Pain




Chapter 147: Nutritional Support




Chapter 148: Sexual Problems




Chapter 149: Psychological Issues




Chapter 150: Communicating News to the Cancer Patient




Chapter 151: Specialized Care of the Terminally III




Chapter 152: Rehabilitation of the Cancer Patient




Chapter 153: Complementary, Alternative, and Integrative Therapies in Cancer Care