Transplantation of the Liver: Expert Consult - Online and Print 3e

Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3rd Edition, which has been thoroughly revised to
offer you the latest protocols, surgical approaches, and techniques used in this challenging procedure. Encompassing
today's expert knowledge in the field, this medical reference book is an ideal single source for authoritative, up-to-
date guidance on every imaginable aspect of liver transplantation.

뷒ccess valuable pearls, pitfalls, and insights from Dr. Ronald Busuttil and Dr. Goran Klintmalm, two of the world's
preeminent experts in liver surgery.
뷫nderstand today's full range of transplantation techniques with complete step-by-step descriptions of each, and
access the background information and management options for each hepatic disease entity.
뷪ake advantage of detailed discussions of everything from pathophysiology and patient and donor selection, to
transplantation anesthesia and operative procedures; immunosuppression; postoperative care; and ethical issues.
뷤vercome your toughest challenges in liver transplantation. Many new and thoroughly revised chapters include: Deceased
Organ Donation after Cardiac and Brain Death; Liver Transplantation for Non-Alcoholic Steatohepatitis; Extended
Criteria Donors; Best Techniques for Biliary and Vascular Reconstruction in Living Donor Transplantation; Small for
Size Syndrome; Dual Grafts for Transplantation; Arterial Reconstructions-Pitfalls; Transition of Pediatric Patients to
Adulthood; Immunosuppressive Biologic Agents; Long Term Toxicity of Immunosuppressive Therapy; Stem Cell and Liver
Regeneration; and Extracorporeal Perfusion for Resuscitation of Marginal Grafts.
뷨tay current in your field and optimize patient outcomes with coverage of the most recent advances in living donor
transplantation, pediatric transplantation, and gene and stem cell therapy.
뷒ccess the latest information on anti-rejection/immunosuppressive drugs, as well as comprehensive discussions of each
drug or combination of drugs used to suppress immune system.
뷙ffortlessly search the entire text online at Expert Consult.

Table of Contents
I: Considerations


1. History of Liver and Multivisceral Transplantation


2. Surgical Anatomy of the Liver


3. Molecular and Cellular Basics of Hepatic Failure


4. Influence of Transplantation on Liver Surgery


5. Liver Allocation: The US Model


6. Liver Allocation: The European Models


7. Donation After Brain Death or Cardiac Death: Regulatory and Ethical Principles

II: Patient Evaluation: Adult


8. Current Indications, Contraindications, De-listing Criteria and Timing for Transplantation


9. Transplantation for Hepatitis A and B


10. Natural History of Hepatitis C


11. Hepatitis C and Transplantation


12. Transplantation for Fulminant Hepatic Failure


13. Transplantation for Primary Biliary Cirrhosis


14. Transplantation for Sclerosing Cholangitis


15. Transplantation for Autoimmune Hepatitis


16. Transplantation for Hepatocellular Carcinoma


17. Transplantation for Cholangiocarcinoma


18. Transplantation for Metastases of the Liver


19. Transplantation for Hematological Disorders


20. Transplantation for Budd-Chiari Syndrome


21. Transplantation for Alcoholic Liver Disease


22. Transplantation for NASH


23. Unusual Indications for Transplantation

III: Patient Evaluation: Pediatric


24. General Criteria for Pediatric Transplantation


25. Transplantation for Cholestatic Liver Disease


26. Transplantation for Biliary Atresia


27. Transplantation for Metabolic Disease


28. Transplantation for Hepatic Malignancy

IV: Special Considerations in Patient Evaluation


29. Ethical Decisions in Transplantation


30. The Psychiatric Assessment of Liver Transplant Candidates


31. Pretransplantation Evaluation: Cardiac


32. Pretransplantation Evaluation: Renal


33. Pretransplantation Infectious Disease Screening for Candidates and Donors


34. Clinical Nurse Coordinator: Nursing Focus on Care of Patients with End-Stage Liver Disease


35. Radiologic Evaluation in the Transplant Patient


36. Monitoring and Care of the Patient Before Transplantation


37. Nutritional Aspects of Adult Transplantation


38. Management of Portal Hypertensive Hemorrhage


39. Portopulmonary Hypertension and Hepatopulmonary Syndrome

V: Operation


40. Donor Selection and Management


41. Extended Criteria Donors


42. Non-Heart Beating Donors


43. Donor Operations


44. Principles of Preservation


45. Recipient Hepatectomy and Grafting


46. Anesthesia for Transplantation

VI: Split and Living Donor Transplantation


47. Imaging Techniques for Partial Grafting


48. Living Related Transplantation in Pediatric Recipients


49. Donor and Recipient Evaluation and Selection for Adult-to-Adult Transplantation


50. Adult Living Donor Right Hepatectomy and Recipient Operation


51. Adult Living Donor Left Hepatectomy and Recipient Operation


52. Split Liver Transplantation for the Pediatric and Adult Recipients


53. Split Liver Transplantation for Two Adults


54. Best Techniques for Biliary and Vascular Reconstruction in Living Donor Transplantation


55. Small for Size Syndrome


56. Minimally Invasive Living Donor Hepatectomy


57. Dual Grafts for Transplantation


58. Outcomes of Living Donor Transplantation: Western Perspective


59. Outcomes of Living Donor Transplantation: Eastern Perspective


60. Ethics of Living Donor Transplantation

VII: Unusual Operative Problems


61. Arterial Reconstructions - Pitfalls


62. Portal Vein Thrombosis and Other Venous Anomalies in Liver Transplantation


63. Combined Liver-Kidney Transplantation


64. Retransplantation


65. Clinical Management of Necrotic Liver During Transplantation


66. Transplantation with Digestive Organs


67. Transplantation and Situs Inversus


68. Auxiliary Transplants

VIII: Postoperative Care


69. Postoperative Intensive Care Management in Adults


70. Postoperative Intensive Care Management in Children


71. Postoperative Management Beyond the Intensive Care Unit: Adults


72. Postoperative Care of Pediatric Transplant Recipients


73. Transition of Pediatric Patients to Adulthood


74. Renal Failure in Adult Transplant Recipients


75. Graft Failure: Etiology, Recognition, and Treatment


76. Technical Problems: Biliary


77. Management of Arterial Complications after Transplantation


78. Infections After Transplantation


79. Recurrent Hepatitis C


80. Late Complications and Recurrence of Disease


81. Neuropsychiatric Outcomes in Recipients


82. Postoperative Neurological Disorders and Prognosis


83. Role of the Posttransplantation Coordinator

IX: Transplant Pathology


84. Histological Patterns of Rejection and Other Causes of Dysfunction


85. Pathology of Recurrence of Non-Neoplastic Disease After Transplantation


86. Transplant Related Malignancies


X: Immunology of Liver Transplantation


87. Rejection After Transplantation


88. Cell Migration, Chimerism, and Graft Acceptance


89. ABO, Tissue Typing, and Crossmatching Incompatibility


90. GVHD after Transplantation

XI: Immunosuppression


91. Induction and Maintenance of Immunosuppression


92. Special Considerations for Pediatric Immunosuppression After Transplantation


93. Treatment of Acute and Chronic Rejection


94. Novel Immunosuppression of Patients with Hepatic Malignancies


95. Non-Biologic New Immunosuppressive Drugs


96. Immunosuppressive Biologic Agents


97. Long-term Toxicity of Immunosuppressive Therapy

XII: Survival and Results


98. Outcome Predictors in Transplantation


99. U.S. Trends in Transplantation: 1988-Present


100. Long-term Functional Recovery and Quality of Life: Childhood, Adulthood, Employment, Pregnancy, and Family Planning


101. Results: Survival and Quality of Life after Transplantation in Children

XIII: Future Developments in Liver Transplantation


102. Genetic and Genomic Potentials in Transplantation


103. Xenotransplantation


104. Hepatocyte Transplantation


105. Stem Cell and Liver Regeneration


106. Ischemia-Reperfusion Injury


107. Extracorporeal Perfusion for Resuscitation of Marginal Grafts


108. Extracorporeal Xenogeneic Support


109. Development of Bioartificial Liver