Cardiac Electrophysiology: From Cell to Bedside 6/e

Cardiac Electrophysiology: From Cell to Bedside puts the latest knowledge in this subspecialty at your fingertips,
giving you a well-rounded, expert grasp of every cardiac electrophysiology issue that affects your patient management.
Drs. Zipes, Jalife, and a host of other world leaders in cardiac electrophysiology use a comprehensive,
multidisciplinary approach to guide you through all of the most recent cardiac drugs, techniques, and technologies.


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Section

Chapter

Title

Part I. Structural and Molecular Bases of Ion Channel Function

1

Voltage-Gated Sodium Channels and Electrical Excitablility of the Heart

Part I. Structural and Molecular Bases of Ion Channel Function

2

Cardiac Calcium Channels

Part I. Structural and Molecular Bases of Ion Channel Function

3

Voltage-Regulated Potassium Channels

Part I. Structural and Molecular Bases of Ion Channel Function

4

Inward Rectifying Potassium Channels

Part I. Structural and Molecular Bases of Ion Channel Function

5

Membrane Pumps and Exchangers

Part I. Structural and Molecular Bases of Ion Channel Function

6

Sarcoplasmic Reticulum Ion Channels

Part I. Structural and Molecular Bases of Ion Channel Function

7

Mitochondrial Ion Channels

Part I. Structural and Molecular Bases of Ion Channel Function

8

Molecular Organization and Regulation of the Cardiac Gap Junction Channel Connexin

Part II. Biophysics of Cardiac Ion Channel Function

9

Biophysics of Normal and Abnormal Cardiac Sodium Channel Function

Part II. Biophysics of Cardiac Ion Channel Function

10

Regulation of Cardiac Calcium Channels

Part II. Biophysics of Cardiac Ion Channel Function

11

Molecular physiology of slow delayed rectifier channels

Part II. Biophysics of Cardiac Ion Channel Function

12

Structural Determinants and biophysical properties of hERG channel gating

Part II. Biophysics of Cardiac Ion Channel Function

13

Molecular regulation of cardiac inward rectifier potassium (KIR) channels by pharmacological agents

Part II. Biophysics of Cardiac Ion Channel Function

14

Cardiac Stretch-Activated Channels

Part II. Biophysics of Cardiac Ion Channel Function

15

Biophysical Properties of Gap Junctions

Part II. Biophysics of Cardiac Ion Channel Function

16

Excitation-Contraction Coupling

Part III. Intermolecular Interactions and Cardiomyocyte Electrical Function

17

Ion Channel Trafficking

Part III. Intermolecular Interactions and Cardiomyocyte Electrical Function

18

Macromolecular Complexes and the Regulation of Sodium Channels

Part III. Intermolecular Interactions and Cardiomyocyte Electrical Function

19

Calmodulin and CaMKII as Ca2+ switches for cardiac ion channels

Part III. Intermolecular Interactions and Cardiomyocyte Electrical Function

20

Macromolecular Complexes and Potassium Channels

Part III. Intermolecular Interactions and Cardiomyocyte Electrical Function

21

Reciprocity of Cardiac Sodium and Potassium channels in the control o Excitability

Part III. Intermolecular Interactions and Cardiomyocyte Electrical Function

22

Moecular Organization of the Intercalated Disc

Part III. Intermolecular Interactions and Cardiomyocyte Electrical Function

23

Scaffolding Proteins and Ion Channel Diseases

Part III. Intermolecular Interactions and Cardiomyocyte Electrical Function

24

Epigenetics in Cardiac Rhythm Diseases

Part IV. Cell Biology of Cardiac Impulse Initiation and Propagation

25

The Sinoatrial Node

Part IV. Cell Biology of Cardiac Impulse Initiation and Propagation

26

Biological Pacemaker therapy

Part IV. Cell Biology of Cardiac Impulse Initiation and Propagation

27

Iintercellular Communication and Impulse Propagation

Part IV. Cell Biology of Cardiac Impulse Initiation and Propagation

28

Mechanisms of AV Nodal Excitability and Propagation

Part IV. Cell Biology of Cardiac Impulse Initiation and Propagation

29

Cell Biology of the Specialized Cardiac Conduction System

Part IV. Cell Biology of Cardiac Impulse Initiation and Propagation

30

Myocyte-Fibroblast Interactions

Part V. Models of Cardiac Excitation

31

IONIC MECHANISMS OF ATRIAL ACTION POTENTIALS

Part V. Models of Cardiac Excitation

32

Models of the Ventricular Action Potential in Health and Disease

Part V. Models of Cardiac Excitation

33

Calcium Signaling in a Cardiomyocyte Model with Realistic Geometry

Part V. Models of Cardiac Excitation

34

Rotors and Spiral Waves in the Heart

Part V. Models of Cardiac Excitation

35

Supraventricular Arrhythmias in a Realistic 3-D model of the Human Atria

Part V. Models of Cardiac Excitation

36

Cardiac Electromechanical Models

Part VI. Neural Control of Cardiac Electrical Activity

37

CaV1.2 and beta adrenergic regulation of cardiac function

Part VI. Neural Control of Cardiac Electrical Activity

38

cholinergic and constitutive regulation of atrial potassium channels

Part VI. Neural Control of Cardiac Electrical Activity

39

Pulomnary vein ganglia and the neural regulation of heart rate

Part VI. Neural Control of Cardiac Electrical Activity

40

Neural activity and atrial tachyarrhythmias

Part VI. Neural Control of Cardiac Electrical Activity

41

Sympathetic denervation and cardiac arrhythmias

Part VII. Arrhythmia Mechanisms

42

Mechanisms of rotor initiation and maintenance in atrial fibrillation

Part VII. Arrhythmia Mechanisms

43

Rotors in Human Atrial Fibrillation

Part VII. Arrhythmia Mechanisms

44

Atrial circulation, atrial ischemia and fibrillation

Part VII. Arrhythmia Mechanisms

45

Molecular pathophysiology of atrial fibrillation

Part VII. Arrhythmia Mechanisms

46

Myofibroblasts, Cytokines and Persistent Atrial Fibrillation

Part VII. Arrhythmia Mechanisms

47

ROLE OF THE AUTONOMIC NERVOUS SYSTEM IN ATRIAL FIBRILLATION

Part VII. Arrhythmia Mechanisms

48

Mechanisms of ventricular tachycardia/fibrillation

Part VIII. Molecular Genetics and Pharmacogenomics

49

Genetics of atrial fibrillation

Part VIII. Molecular Genetics and Pharmacogenomics

50

Inheritable Sodium Channel Diseases (Long QT Syndrome, Brugada Syndrome)

Part VIII. Molecular Genetics and Pharmacogenomics

51

Inheritable potassium channel diseases

Part VIII. Molecular Genetics and Pharmacogenomics

52

Arrhythmia Mechanisms in the J Wave Syndrome

Part VIII. Molecular Genetics and Pharmacogenomics

53

Inheritable Diseases of Intracellular Calcium Regulation (CPVT, HCM)

Part IX. Pharmacologic, Genetic and Cell Therapy of Ion Channel Dysfunction

54

Pharmacologic bases of antiarrhythmic therapy

Part IX. Pharmacologic, Genetic and Cell Therapy of Ion Channel Dysfunction

55

Pharmacogenomics of cardiac arrhythmias

Part IX. Pharmacologic, Genetic and Cell Therapy of Ion Channel Dysfunction

56

Optogenetic control of heart muscle

Part IX. Pharmacologic, Genetic and Cell Therapy of Ion Channel Dysfunction

57

Cell therapy and regeneartive electrophysiology

Part X. Diagnostic Evaluation

58

Assessment and Diagnosis of the Patient with a Cardiac Arrhythmia

Part X. Diagnostic Evaluation

59

Differential Diagnosis of Narrow and Wide Complex Tachycardias

Part X. Diagnostic Evaluation

60

EP Mapping and Navigation

Part X. Diagnostic Evaluation

61

CT and MR Imaging for electrophysiology

Part X. Diagnostic Evaluation

62

Intracardiac echocardiography for electrophysiology

Part X. Diagnostic Evaluation

63

Exercise -induced arrhythmias

Part X. Diagnostic Evaluation

64

Holter, event and long term recordings

Part X. Diagnostic Evaluation

65

Electrocardiographic imaging in patients with acute coronary syndrome

Part X. Diagnostic Evaluation

66

Head-up Tilt Table Testing

Part X. Diagnostic Evaluation

67

Electrocardiographic and autonomic testing

Part X. Diagnostic Evaluation

68

Monophasic Action Potential Recording

Part X. Diagnostic Evaluation

69

T-Wave Alternans

Part X. Diagnostic Evaluation

70

Noninvasive Electrocardiographic Imaging (ECGI) of human ventricular arrhythmias and electrophysiologic substrate

Part X. Diagnostic Evaluation

71

Genetic testing

Part XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

72

Sinus node abnormalities

Part XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

73

Atrial tachycardia: focal, multifocal, and macroreentrant

Part XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

74

Atrial flutter: typical and atypical

Part XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

75

Atrial fibrillation: paroxysmal, persistent, and permanent

Part XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

76

Preexcitation and atrioventricular reentrant tachycardia, variants

Part XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

77

Atrioventricular nodal reentrant tachycardia, variants

Part XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

78

Atrial arrhythmias in congenital heart disease, pre and post surgical repair

Part XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management

79

Junctional tachycardia

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

80

Premature ventricular complexes

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

81

Outflow Tract

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

82

Fascicular

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

83

Bundle branch reentry

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

84

Ischemic heart disease

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

85

Nonischemic dilated cardiomyopathy

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

86

Hypertrophic cardiomyopathy

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

87

Right ventricular cardiomyopathy

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

88

Catecholaminergic cardiomyopathy

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

89

Heart Failure

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

90

Noncompaction cardiomyopathy

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

91

Takatsubo cardiomyopathy

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

92

Brugada syndrome

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

93

Long and short QT syndromes

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

94

Andersen-Tawil syndrome

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

95

Timothy syndrome

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

96

J wave syndromes

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

97

Idiopathic ventricular fibrillation

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

98

Sudden infant death syndrome

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

99

Sudden cardiac arrest/death in adults

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

100

Neurologic disorders

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

101

Drug induced

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

102

Congenital heart disease, pre and post surgical repair

Part XII. Ventricular Tacharrhythmias: Mechanisms, Cliinical Features, and Management

103

Parasystole

Part XIII. Syncope and AV Block

104

Syncope

Part XIII. Syncope and AV Block

105

Postural orthostatic tachycardia syndrome

Part XIII. Syncope and AV Block

106

Progressive conduction system disease

Part XIII. Syncope and AV Block

107

Atrioventricular block

Part XIV. Arrhythmias in Special Populations

108

Gender Differences in Arrhythmias

Part XIV. Arrhythmias in Special Populations

109

Arrhythmias in Athletes

Part XIV. Arrhythmias in Special Populations

110

Arrhythmias in Pediatric Age Group

Part XIV. Arrhythmias in Special Populations

111

Sleep Disordered Breathing and Arrhythmias

Part XV. Pharmocologic Therapy

112

Standard Antiarrhythmic Drugs

Part XV. Pharmocologic Therapy

113

New Antiarrhythmic Drugs

Part XV. Pharmocologic Therapy

114

Impact of Nontraditional Antiarrhythmic Drugs (Including CAM) on Sudden Cardiac Death

Part XV. Pharmocologic Therapy

115

Prevention of Thromboemboli in Valvular and Non-Valvular Atrial Fibrillaiton

Part XVI. Electrical Therapy

116

Implantable Cardioverter-Defibrillators: Technical Aspects

Part XVI. Electrical Therapy

117

Implantable Cardioverter-Defibrillators: Clinical Aspects

Part XVI. Electrical Therapy

118

Implantable Pacemakers

Part XVI. Electrical Therapy

119

Cardiac Resynchronization Therapy

Part XVI. Electrical Therapy

120

Newer Applications of Pacemakers

Part XVI. Electrical Therapy

121

Catheter ablation: Technical aspects

Part XVI. Electrical Therapy

122

Catheter ablation: Clinical aspects

Part XVI. Electrical Therapy

123

Ablation for Atrial fibrillation

Part XVI. Electrical Therapy

124

Ablation of Supraventricular tachyarrhythmias

Part XVI. Electrical Therapy

125

Ablation of Ventricular tachyarrhythmias

Part XVI. Electrical Therapy

126

Special ablation approaches: epicardial, other

Part XVI. Electrical Therapy

127

Ablation in Pediatrics

Part XVI. Electrical Therapy

128

Catheter Ablation in Patients with Congenital Heart Disease

Part XVII. Surgery for Arrhythmias

129

Atrial fibrillation and other SVTs

Part XVII. Surgery for Arrhythmias

130

Ventricular arrhythmias

Part XVIII. New Approaches

131

Vagal stimulation

Part XVIII. New Approaches

132

Spinal cord stimulation

Part XVIII. New Approaches

133

Left atrial occluders/isolation