Liver Disease in Children 4/e

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd
Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents.
Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of
these disorders in the pediatric population. The third edition has been thoroughly updated and features new
contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of
metabolism. An essential resource for all physicians involved in the care of children with liver disease.
This book contains black-and-white illustrations.


Table of Contents
Preface; Part I. Pathophysiology of Pediatric Liver Disease: 1. Liver development Yiwei Zong and Joshua R. Friedman; 2.
Functional development of the liver Frederick J. Suchy; 3. Mechanisms of bile formation and cholestasis Nitika A. Gupta
and Saul J. Karpen; 4. Acute liver failure in children Robert H. Squires and Estella M. Alonso; 5. Cirrhosis and
chronic liver failure Evelyn K. Hsu and Karen F. Murray; 6. Portal hypertension Benjamin L. Shneider; 7. Laboratory
assessment of liver function and injury in children Vicky Lee Ng; Part II. Cholestatic Liver Disease: 8. Approach to
the infant with cholestasis Amy Feldman and Frederick J. Suchy; 9. Medical and nutritional management of cholestasis in
infants and children Andrew P. Feranchak, Frederick J. Suchy and Ronald J. Sokol; 10. Neonatal hepatitis and congenital
infections Philip Rosenthal; 11. Biliary atresia and other disorders of the extrahepatic bile ducts William F.
Balistreri, Jorge A. Bezerra and Frederick C. Ryckman; 12. Neonatal jaundice and disorders of bilirubin metabolism Mark
Bartlett and Glenn R. Gourley; 13. Familial hepatocellular cholestasis Frederick J. Suchy, Shikha S. Sundaram and
Benjamin L. Shneider; 14. Alagille syndrome Binita M. Kamath, Nancy B. Spinner and David A. Piccoli; 15. Intestinal
failure associated liver disease Jason Soden and Ronald J. Sokol; 16. Disease of the gallbladder in infancy, childhood,
and adolescence Frank W. DiPaola and James E. Heubi; Part III. Hepatitis and Immune Disorders: 17. Hepatitis A and
hepatitis E virus infection Philip Rosenthal; 18. Hepatitis B virus infection Mei-Hwei Chang; 19. Hepatitis C virus
infection Maureen M. Jonas; 20. Autoimmune hepatitis Nanda Kerkar and Cara L. Mack; 21. Sclerosing cholangitis
Alexander G. Miethke and William F. Balistreri; 22. Drug-induced liver disease Eve A. Roberts; 23. Liver disease in
immunodeficiencies Nedim Hadžić; Part IV. Metabolic Liver Disease: 24. Laboratory diagnosis of inborn errors of
metabolism Piero Rinaldo; 25. α1-antitrypsin deficiency David H. Perlmutter; 26. Cystic fibrosis liver disease Meghana
Sathe and Andrew P. Feranchak; 27. Inborn errors of carbohydrate metabolism Rana F. Ammoury and Fayez K. Ghishan; 28.
Copper metabolism and copper storage disorders Ronald J. Sokol; 29. Iron storage disorders Michael R. Narkewicz and
Peter F. Whittington; 30. Heme biosynthesis and the porphyrias Robert J. Desnick, Manisha Balwani and Karl E. Anderson;
31. Tyrosinemia Grant Mitchell, Pierre A. Russo, Josée Dubois and Fernando Alvarez; 32. Lysosomal storage disorders T.
Andrew Burrow and Gregory A. Grabowski; 33. Disorders of bile acid synthesis and metabolism Kenneth D. R. Setchell; 34.
Inborn errors of fatty acid oxidation Melanie B. Gillingham and Robert B. Steiner; 35. Mitochondrial hepatopathies
Ronald J. Sokol; 36. Nonalcoholic fatty liver disease in children Rohit Kohli, Kevin E. Bove and Stavra A. Xanthakos;
37. Peroxisomal diseases Paul A. Watkins and Kathleen B. Schwarz; 38. Urea cycle disorders Derek Wong and Stephen
Cederbaum; Part V. Other Considerations and Issues in Pediatric Hepatology: 39. Bacterial, parasitic, and fungal
infections of the liver Donald A. Novak, Gregory Y. Lauwers and Richard L. Kradin; 40. Systemic disease and the liver
Kathleen M. Campbell; 41. Fibrocystic liver disease Ronen Arnon, Maureen M. Jonas, Antonio R. Perez-Atayde and
Frederick J. Suchy; 42. Tumors of the liver Dolores López-Terrada and Milton J. Finegold; 43. Liver transplantation in
children: indications and surgical aspects M. Kyle Jensen, Maria H. Alonso, Jaimie D. Nathan, Frederick C. Ryckman,
Gregory M. Tiao and William F. Balistreri; 44. Liver transplantation in children: post-transplant care Estella M.
Alonso and Riccardo A. Superina; Index.