Fields Virology 6/e

Fields Virology is the authoritative reference book for virology, providing definitive coverage of all aspects of
virology, including thorough coverage of virus biology as well as replication and medical aspects of specific virus
families. With the regular outbreaks of influenza, noroviruses as well as other emerging and re-emerging viruses it is
essential to have the most up-to-date information available.

With this Sixth Edition, all chapters have been completely updated, an important new emphasis has been placed on virus
discovery and emerging viruses. Viruses associated with cancer, including the new human polyomaviruses, are highlighted
in this Sixth Edition and new chapters have been added on circoviruses and mimiviruses.

While the main focus of this edition continues to be on viruses, information on prions and the infectious spongiform
encephalopathies are also included.

FEATURES
?Full color throughout with over 1,000 illustrations in total and most chapters provide key figures for use as lecture
slides
?Online companion website with fully searchable text, all references linked to PubMed and additional material not
found in the print for access to content anytime
?New coverage of emerging and viruses, including those causing influenza and HIV
?Updated coverage of viruses and cancer
?Coverage includes virus structure, virus entry, replication, and assembly, virus-host cell interactions, host immune
responses and vaccines, antiviral therapeutics, virus evolution and immunization
?Thorough coverage of all viruses of medical importance, including both basic science and clinical features
?New chapters on circoviruses and mimiviruses and a new section on Chikungunya virus have been added
?Important advances in antivirals, including new HCV protease inhibitors and HIV integrase inhibitors


Table of Contents
History of Virology

Principles of Virology

Principles of Virus Structure

Virus Entry and Uncoating

Virus Replication Strategies

Virus Assembly

Viral Conquest of the Host Cell

Cellular Transformation by Viruses

Innate Responses to Viral Infection

Adaptive Immune Responses to Viral Infection

Pathogenesis of Viral Infections

Virus Evolution

Epidemiology

Antiviral Agents

Immunization Against Viral Diseases

Virus Vectors and Their Applications

Diagnostic Virology

Viruses and Biodefense

Emerging and Re-Emerging Viruses

The Virus World ("The Virome")

Plant Viruses

Insect Viruses

Viruses and Prions of Yeasts, Fungi, and Unicellular Organisms

Bacteriophages

Picornaviridae: The Viruses and Their Replication

Enteroviruses: Polioviruses, Coxsackievirus, Echoviruses, and Newer Enteroviruses

Rhinoviruses

Hepatitis A Virus

Human Caliciviriuses

Astroviruses

Togaviridae

Alphaviruses

Rubella Virus

Flaviviridae: The Viruses and Their Replication

Flaviviruses

Hepatitis C Viruses

Nidovirales: Coronoviridae and Ateriviridae

Coronaviridae

Arteriviruses

Mononegavirales

Rhabdoviridae

Filoviridae: Marburg and Ebola Viruses

Paramyxoviridae: The Viruses and Their Replication

Parainfluenza Viruses

Mumps Virus

Measles Virus

Henipaviruses

Respiratory Syncytial Virus and Metapneumoviruses

Orthomyxoviridae: The Viruses and Their Replication

Orthomyxoviruses

Bunyaviridae

Arenaviridae

Bornaviridae

Reoviruses

Rotaviruses

Orbiviruses

Retroviridae: The Retroviruses and Their Replication

Human T-Cell Leukemia Virus Types I and II

HIVs and Their Replication

Human Immunodeficiency Virus

Nonhuman Lentiviruses

Other Human and Primate Retroviruses

Polyomaviridae

Papillomaviridae

Adenoviridae: The Viruses and Their Replication

Adenoviruses

Parvoviridae

The Herpesviridae Family: A Brief Introduction

Herpes Simplex Viruses

Epstein-Barr Virus

Cytomegaloviruses

Varicella-Zoster Virus

Human Herpesviruses 6A, 6B, and 7

Kaposi's Sarcoma-Associated Herpesvirus

Cercopithecine Herpesvirus (B Virus)

Poxviridae: The Viruses and Their Replication

Poxviruses

Hepadnaviridae

Hepatitis Delta Virus

Hepatitis E Virus

Prions