Tumors of the Pediatric Central Nervous System 2/e

Praise for the first edition:
A superb overview ... each chapter is well written and concise ... provides a succinct summary of the clinical,
radiological, and pathological features of each tumor ... a useful reference for the treatment of pediatric central
nervous system tumors. ?Journal of Neurosurgery

Tumors of the Pediatric Central Nervous System, Second Edition, provides readers with both medical management and
surgical perspectives on the clinical, pathological, and radiological diagnoses and treatment of pediatric CNS tumors.
It includes complete coverage of the latest diagnostic and management techniques, state-of-the-art technologies, and
trends in the surgical treatment of pediatric tumors.

Highlights of the Second Edition:

Contains 19 new chapters on such topics as recent advances in the cytogenetics and molecular biology of pediatric brain
tumors, gangliogliomas and miscellaneous spinal cord tumors in children, post-chemotherapy morbidity, and many more
Addresses the important issues of long-term chronic treatment of pediatric tumor patients and related outcome measures
Includes summary boxes and tables that distill large amounts of information for quick review
Written by editors and contributors who are world-renowned experts in the field of pediatric neurosurgery and oncology
Neurosurgeons, neurologists, oncologists, radiation oncologists, and pediatricians caring for patients with tumors of
the central nervous system will find this book to be an essential resource that they will repeatedly consult as they
strive to enhance patient care.



Contributors
Foreword
Preface
1 Pediatric Neuro-oncology: A Historical Perspective 3
2 Epidemiology of Brain Tumors 14
3 Diagnostic Principles 22
4 Neuroradiology 27
5 Surgical Neuropathology 44
6 Anesthetic Considerations 103
7 Critical Care Considerations 110
8 Radiotherapy 135
9 Stereotactic Radiosurgery 157
10 Chemotherapy 168
11 Gene Therapy 184
12 Infratentorial Astrocytoma 199
13 Brain Stem Tumors 206
14 Supratentorial Astrocytoma 221
15 Infratentorial Ependymoma 232
16 Supratentorial Ependymoma 239
17 Infratentorial Primitive Neuroectodermal Tumors 251
18 Supratentorial Primitive Neuroectodermal Tumors 265
19 Craniopharyngioma 276
20 Pituitary Tumors 292
21 Optic Nerve Glioma 302
22 Pineal Region Tumors 308
23 Phakomatoses 326
24 Choroid Plexus Tumors 339
25 Intracranial Meningioma 351
26 Oligodendroglioma 361
27 Extraneural Metastasis 367
28 Infantile Brain Tumors 376
29 Miscellaneous Brain Tumors 398
30 Astrocytoma 415
31 Ependymoma 423
32 Neurofibromatosis 436
33 Peripheral Nerve Tumors 453
34 Uncommon Pediatric Spinal Cord Tumors 464
35 Postoperative Considerations 477
36 Rehabilitation 502
37 Cooperative Group Trials 511
38 Chemosensitivity Testing 524
39 Late Effects of Therapy in Long-Term Survivors 535
40 Ethical Issues in Pediatric Neuro-oncology 541
Index