01 History
References
02 Donor Evaluation
Introduction
Steps in Donor Evaluation
Step 1
Step 2a
Step 2b
Step 3
Step 4
Outcome of Donor Evaluation
High-Urgency versus Elective LDLT
Complications of Donor Evaluation
Summary
References
Annex I
Annex II
03 Psychological Assessment of Recipients and Donors in Liver Transplantation
Introduction
Psychological Work with Recipients of Liver Transplantation
Aims and process
Psychological Work with Potential Donors of Liver Transplantation
Aims and process
The Issue of Screening Out Potential Donors
Some Observed Psychosocial Issues
Collectivistic pressures
Pressures on females
Donor motivation and conflicting needs
Balancing conflicting demands to achieve a truly informed consent
Pressure on donor
Expectations on donor-recipient relationship
The issue of gains
Urgent versus Elective Transplantation
Influence of the Transplant Team Members and the Workup Procedure
Conclusion and Summary
References
Annex I
Annex II
Annex III
04 Segment II/III Graft
Donor Operation
Recipient Operation
Postoperative Care
References
05 Left Liver Graft (Including the Caudate and the Middle Hepatic Vein)
Donor Operation
Recipient Operation
Postoperative Care
References
06 Right Liver Graft (Including the Middle Hepatic Vein)
Donor Operation
Backtable Procedure
Recipient Operation
Postoperative Care
References
07 Microvascular Technique of Hepatic Artery Anastomosis
Introduction
Microvascular Surgery Technique
Instrument
Microinstruments
Microsutures
Other accessories
Position of Instruments and Exposure
Selection and Preparation of Vessel Ends
Microvascular Anastomosis Techniques
Solutions to Problems Encountered
Bleeding
Separation of intima from media
Catching the posterior wall
Anastomosis in deep wounds
Movement of vessel ends
Special Situations
Short vessel ends
Anastomosis of two vessels
Shortage of recipient artery
References
08 Anesthesia Management of the Adult Liver Transplant Recipient and Living Donor
Preoperative Assessment
Anesthesia Technique
Intraoperative Set-Up
Cell Salvage
Monitoring
Warming Measures
The Pre-Anhepatic Stage
The Anhepatic Phase
Veno-Venous Bypass
Management of Reperfusion
The Post-Anhepatic Phase
Anesthesia Management of the Living Donor
References
09 Anesthesia for Pediatric Liver Transplantation
Introduction
Indications for Liver Transplantation
Prioritization of Patients for Liver Transplantation
Clinical Manifestations of End-Stage Liver Disease
Cardiovascular system
Respiratory system
Renal system
Neurological system
Gastrointestinal system
Hematological system
Metabolic derangement
Fulminant hepatic failure
Anesthetic Management
Preoperative assessment
Preoperative preparation
Induction and maintenance of anesthesia
Congenital Heart Disease and Liver Transplantation
References
10 Perioperative ICU Care of Donors and Recipients
Donor Care
Transfer of Liver Failure Patients
Renal Issues
Diagnosis
Prevention of renal failure
Hepatorenal syndrome
Renal failure after transplantation
Renal replacement therapy
Anticoagulation in Liver Failure
Cardiac and Hemodynamic Issues
Cardiac conditions in liver failure
Cardiovascular assessment
Central venous pressure
Arrhythmia
Cardiac arrest
Pulmonary Issues
Pulmonary edema
Pneumonia
Hepatopulmonary syndrome
Portopulmonary Hypertension
Neurological Issues
Hepatic encephalopathy
Nursing management
Pharmacological therapies for hepatic encephalopathy
Sedation and tranquilizers
Central pontine myelinolysis
Endocrine Issues
Adrenal insufficiency
Glycemic control in liver failure
Artificial Liver Support
Nutrition
Drug Issues
Tacrolimus
Mycophenolate mofetil (MMF)
Basiliximab (Simulect)
Sirolimus
References
11 The Middle Hepatic Vein Controversy
Introduction
Anatomy of the MHV
Venous Drainage of Segment IV
Disadvantages of Not Including the MHV in the Right Liver Graft
Donor Risk
Reconstruction of Segment V and VIII Hepatic Veins
Conclusion
References
12 Biliary Complications of Right Liver LDLT
Introduction
Anatomy
Preoperative Recognition of Biliary Anatomy
Donor Intraoperative Cholangiography
Bile Leakage in the Donor
Injury to the Confluence of Hepatic Ducts in the Donor
Preparation of Recipient Common Hepatic Duct for Duct-to-Duct Anastomosis
Duct-to-Duct Anastomosis
Suturing method
Suture material
Stenting of anastomosis
Hepaticojejunostomy
Bile Leakage in the Recipient
Anastomotic Stenosis
Our Results
Conclusion
References
13 Small-for-Size Graft and Injury
Minimum Graft Size Required for a Recipient
Definitions
Histopathological Changes
Mechanism of Injury
Strategies to Rescue Small-for-Size Graft after Reperfusion
Impact of Small-for-Size Graft Injury
Summary
References
14 Donor Results
Our Results
Morbidity and mortality
Results of Other Centers
Comments on Donor Hepatectomy Complications
Long-Term Outcome
Conclusion
References
15 Recipient Results
Our Results
Results of Other Centers
LDLT versus DDLT
Acute Liver Failure
Left Liver Graft versus Right Liver Graft
Hepatocellular Carcinoma
Hepatitis B
Hepatitis C
Conclusion
References
Index이 책의 특징
The book describes in detail the technical aspects of Living Donor Liver Transplantation (LDLT), the routine practice
of the world renowned Liver Transplant Team at Hong Kong's Queen Mary Hospital, and our views on various issues of the
operation. The thorough review on the history and technical procedures of LDLT and discussion on various aspects of the
operation and its future perspectives will serve as a unique reference for surgeons, researchers, nurses, medical
students, patients and laypersons seeking information on LDLT.
This latest edition offers updated operative results from our center and the latest modifications of the technique.
With contributions from a leading microvascular surgeon, a critical care clinician, a psychiatrist, and two
anesthetists from the same liver transplant team, the LDLT experience at Queen Mary Hospital is depicted in an even
greater extent.