Pathfinder of Bone Tumor

머리말

Twenty years ago, when I was a callow fellow who hatched out of the residency program, my initial intent was just
having a taste of specialized orthopedic field. Nevertheless, sometimes flattering myself as being a fairly good tumor
surgeon, I have been engaged in orthopedic oncology ever since. However, about 6 years ago, I realized that all I know
was how to perform surgery rather than understanding the disease itself. Clearly, my lack of perspicacity would be
largely responsible for this kind of enlightenment that came too late; still, there seems to be additional factors
that
make difficult to figure out the pathophysiology underlying the bone tumors.

Firstly, the various diagnostic groupings, the relatively low incidence and prevalence of many of the diagnoses, and
the myriad radiologic feature make bone tumor a source of anxiety.

Secondly, the majority of textbooks are limited to describe the whole spectrum of management, i.e., radiology and
pathology texts focus on the diagnosis while surgery texts more concentrate on the surgical procedure. Further, those
texts usually demonstrate typical findings only. As such, the field of bone tumors intimidates to surgical or medical
trainee and even to experienced practitioners.

Accordingly, I tried to construct a textbook encompassing radiologic diagnosis, treatment, complication, and ultimate
outcome. For better understanding of the disease, this book consists mainly of the radiologic images including various
atypical presentations. Through this book, it is hoped that awareness of these interesting, not infrequently fatal
neoplasm can be raised among medical personnel.

Dae-Geun Jeon, MD, MBA

August, 2012



목차



Part 1 General Principle of Bone Tumors _11

1. Classification of bone tumors 13

2. Diagnostic Evaluation 21

3. Biopsy 45

4. Staging 55

5. Principle of Surgery 63

6. Adjuvant treatment 101

7. Post-treatment surveillance 111





Part 2 Benign Bone Tumors and Non-neoplastic conditions simulating bone tumors _117

8. Bone forming tumors 119

9. Cartilage lesions 129

10. Fibrous lesions 151

11. Cystic lesions 177

12. Fatty tumors 197

13. Vascular tumors 201

14. Other non-neoplastic lesions 207





Part 3 Benign/Aggressive Tumors of Bone _225

15. Giant cell tumor 227

16. Chondroblastoma 253

17. Chondromyxoid Fibroma 263

18. Osteoblastoma 269

19. Langerhans Cell Histiocytosis 275




Part 4 Malignant Bone Tumor _285

20. Osteosarcoma 287

21. Chondrosarcoma 345

22. Ewing Sarcoma 377

23. Chordoma 391

24. Adamantinoma 397

25. Malignant vascular tumors 405

26. Maligant fibrous histiocytoma (MFH) and fibrosarcoma 409

27. Multiple myeloma and plasmacytoma 421

28. Lymphoma 431

29. Metastatic Carcinoma 441



INDEX _461