Practical Hepatic Pathology: A Diagnostic Approach

Practical Hepatic Pathology-a new volume in the new Pattern Recognition series-offers you a practical guide to
diagnosing every challenging liver biopsy that you encounter in your daily practice. Dr. Romil Saxena presents
diagnoses according to a pattern-based organization that guides you from a histological pattern of injury, through the
appropriate work-up, around the pitfalls, and to the best diagnosis. Lavish, full-color images capture key hepatic
pathology patterns of injury, pathognomonic features and common variations of all major liver diseases and hepatic
neoplasms, while a "visual index" at the beginning of the book directs you to the exact location of in-depth diagnostic
guidance. No other single source delivers the practical, hands-on information you need to solve even the toughest
diagnostic challenges in liver biopsies.

Key Features
Access the fully searchable contents online at www.expertconsult.com, along with a downloadable image bank.

Recognize the basic patterns of liver injury through an algorithmic approach and establish diagnosis by a pattern-based
visual index present at the beginning of the book.


Evaluate and interpret biopsy samples using superb, high-quality, full-color images that illustrate pathognomonic
features and common variations.


Get comprehensive information on major adult and childhood liver diseases, hepatic neoplasms and pre-neoplastic nodules
including clinical features, laboratory tests, imaging findings and differential diagnosis.


Understand the pathology and practice of liver transplantation with coverage of the clinical aspects of this procedure.

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Table of Contents
Section I: Applied Anatomy and Pathophysiology

1. Microscopic Anatomy, Basic Terms, and Elemental Lesions


2. Immunobiology of the Liver


3. Bile Physiology and Transporter Proteins


4. Metabolism of Drugs and Xenobiotics


Section II: Clinical Features, Laboratory tests and Imaging

5. Laboratory Tests in Liver Disease


6. Clinical Features of Liver Disease


7. Investigative Imaging of the Liver


Section III: Common Liver Diseases of Childhood

8. Common Liver Diseases of Childhood


Section IV. Inherited and Metabolic Disorders

9. Medical Genetics and Biochemistry in Diagnosis and Management


10. Histologic Patterns of Metabolic Disease


11. Intrahepatic Cholestasis: Inherited Disorders


12. Wilson Disease


13. Alpha-1 Antitrypsin Deficiency


14. Hemachromatosis


15. Cystic Fibrosis


Section V: Infectious Diseases

16. Chronic Hepatitis: Grading and Staging


17. Hepatitis B


18. Hepatitis C


19. Acute Viral Hepatitides


20. Nonviral Infections of the Liver


21. Human Immunodeficiency Virus Infection


Section VI: Granulomatous Diseases


22. Hepatic Granulomas: Differential Diagnosis


23. Hepatic Sarcoidosis


Section VII: Drug-Induced Liver Injury

24. Liver Injury Due to Drugs and Herbal Agents


Section VIII: Disorders of the Bile Ducts

25. Fibrocystic Liver Diseases


26. Primary Biliary Cirrhosis


27. Primary Sclerosing Cholangitis


28. Loss of Intrahepatic Bile Ducts in Adults


Section IX: Autoimmune Hepatitis

29. Autoimmune Hepatitis and Overlap Syndromes


Section X: Fatty Liver Disease

30. Alcohol-Induced Liver Disease


31. Nonalcoholic Fatty Liver Disease


Section XI: Vascular Disorders

32. Vascular Disorders of the Liver


Section XII: Liver Tumors and Tumor-like Lesions

33. Premalignant Hepatocellular Lesions


34. Benign Hepatocellular Tumors


35. Hepatocellular Carcinoma


36. Benign and Malignant Tumors of Bile Ducts


37. Mixed Hepatobiliary Carcinoma


38. Liver Tumors of Childhood


39. Miscellaneous Tumors and Tumor-like Lesions


Section XIII: Systemic Diseases and Diseases of Other Organs

40. Liver Pathology in Systemic Diseases and Diseases of Other Organs


Section XIV: Liver Transplantation

41. Clinical Aspects of Liver Transplantation


42. Pathology of Liver Transplantation


Index