Mechanical Circulatory Support: A Companion to Braunwald's Heart Disease

Mechanical Circulatory Support, by Drs. Robert L. Kormos and Leslie W. Miller, provides the clinically relevant

information you need to effectively use this therapy to treat and manage end-stage cardiovascular disease. In this

Companion to Braunwald’s Heart Disease, the world’s most prominent experts in mechanical circulatory support (MCS)

cover basic science, device construction, clinical applications, socioeconomic implications, future directions, and

more. Stay on top of hot topics - including innovative devices like continuous flow pumps, next-generation centrifugal

pumps, and total artificial hearts; MCS for pediatric and congenital heart disease; cellular, molecular, genomic, and

functional changes that occur in the failing heart in response to MCS; and Interagency Registry of Mechanically

Assisted Circulatory Support (INTERMACS) as a tool to track and advance clinical practice. You’ll also have access the

fully searchable text online at www.expertconsult.com.





Table of Contents

1. Historical Aspects of Mechanical Circulatory Support





2. The Potential Population for Chronic Use of Mechanical Circulatory Support





3. Acute Decompensated Heart Failure





4. Chronic Stage D Heart Failure





5. Risk Factors for Mortality with Heart Failure





6. Candidate Selection for Chronic Left Ventricular Assist Device Therapy for Advanced Heart Failure





7. Preoperative Patient Optimization for Mechanical Circulatory Support





8. Current Types of Devices for Mechanical Circulatory Support





9. Special Clinical Settings for Mechanical Circulatory Support





10. Preoperative Anesthesia assessment/preparation





11. Surgical Methods for Mechanical Circulatory Support





12. Intraoperative Management Issues in Mechanical Circulatory Support





13. Adverse Events and Complications of Mechanical Circulatory Support





14. Pre-Discharge and Outpatient Management





15. Psychosocial and Quality of Life Issues in Mechanical Circulatory Support





16. Mechanical Circulatory Support in Pediatrics





17. Myocardial Recovery with Use of Mechanical Circulatory Support





18. Regenerative Therapy as an Adjunct to Recovery with MCS





19. Biologic Responses to the Interface Between Device and Circulation: Bleeding and Thrombosis with MCS





20. Cellular, Molecular, Genomic, and Functional Changes that Occur in the Failing Heart in Response to Mechanical

Circulatory Support





21. Results of Clinical Trials to Date





22. Design Challenges for Clinical Trials in Mechanical Circulatory Support





23. Regulatory Framework for Mechanical Circulatory Support





24. Interagency Registry of Mechanically Assisted Circulatory Support (INTERMACS) as a Tool to Track and Advance

Clinical Practice





25. Reimbursement and Funding Framework for Mechanical Circulatory Support





26. The Future of Mechanical Circulatory Support