Tietz Textbook of Clinical Chemistry and Molecular Diagnostics-5판

As the definitive reference for clinical chemistry, Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 5th
Edition offers the most current and authoritative guidance on selecting, performing, and evaluating results of new and
established laboratory tests. Up-to-date encyclopedic coverage details everything you need to know, including:
analytical criteria for the medical usefulness of laboratory procedures; new approaches for establishing reference
ranges; variables that affect tests and results; the impact of modern analytical tools on lab management and costs; and
applications of statistical methods. In addition to updated content throughout, this two-color edition also features a
new chapter on hemostasis and the latest advances in molecular diagnostics.

Table of Contents
Section I: Principles of Laboratory Medicine


Introduction to Laboratory Medicine


Selection and Analytical Evaluation of Methods&' || 'nbsp;- With Statistical Techniques


Clinical Evaluation of Methods


Evidence Based Laboratory Medicine


Establishment and Use of Reference Values


Preanalytical Variables and Biological Variation


Specimen Collection and Processing


Quality Management

Section II: Analytical Techniques and Instrumentation


Principles of Basic Techniques and Laboratory Safety


Optical Techniques


Electrochemistry and Chemical Sensors


Electrophoresis


Chromatography and Extraction


Mass Spectrometry


Enzyme and Rate Analyses


Principles of Immunochemical Techniques


Nucleic Acid Techniques


Microfabrication and Microfluidics and Their Application to Clinical Diagnostics


Automation in the Clinical Laboratory


Point-of-Care Testing

Section III: Analytes


Amino Acids, Peptides, and Proteins


Serum Enzymes


Enzymes of the Red Blood Cell


Tumor Markers


Kidney Function Tests


Carbohydrates


Lipids, Lipoproteins, Apolipoproteins, and Other Cardiovascular Risk Factors


Electrolytes and Blood Gases


Hormones


Catecholamines and Serotonin


Vitamins and Trace Elements


Hemoglobin, Iron, and Bilirubin


The Porphyrias and Other Disorders of Porphyrin Metabolism


Therapeutic Drugs and Their Management


Clinical Toxicology


Toxic Metals

Section IV: Molecular Diagnostics and Genetics


Principles of Molecular Biology


Genomes and Nucleic Acid Alterations


Nucleic Acid Isolation


Inherited Diseases


Identity Assessment


Molecular Methods in Diagnosis and Monitoring of Infectious Diseases


Pharmacogenetics


Hematopoietic Malignancies


Plasma Nucleic Acids

Section V: Pathophysiology


Diabetes Mellitus


Cardiovascular Disease


Kidney Disease


Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism


Liver Disease


Gastrointestinal and Pancreatic Diseases


Disorders of Bone and Mineral Metabolism


Pituitary Function and Pathophysiology


The Adrenal Cortex


The Thyroid: Pathophysiology and Thyroid Function Testing


Reproductive Endocrinology and Related Disorders


Pregnancy and its Disorders


Newborn Screening and Inborn Errors of Metabolism


Hemostasis

Section VI: Appendix


Reference Information for the Clinical Laboratory