Pediatric Hematology and Oncology: Scientific Principles and Clinical Practice

Hardcover - 448 pages



This new textbook has an international authorship and is a practical, up-to-date resource for clinicians responsible
for the care of children with oncologic and malignant hematologic disease. It is specifically designed for practicing
oncologists and hematologists, pediatricians with an interest in childhood cancer and trainees seeking a systematic
approach to these disorders. This new textbook has an emphasis on the visual presentation and ease of reading of
contemporary and comprehensive information for children’s cancers and contains detailed tables, fact boxes and
illustrations.
The textbook begins with an introduction to the general principles of the scientific foundation and treatment of
childhood cancers and hematological malignancies. Separate sections are then devoted to descriptions of central nervous
system tumors, hematological malignancies and solid tumors of childhood which encompass epidemiology, cellular and
molecular biology, cancer genetics, immunology, pharmacology and the findings of clinical trials. For each area of
science covered, key original references and reviews are highlighted to direct further reading.

Diagnostic, biological, and therapeutic issues are integrated into each tumor-specific chapter, with evidence
supporting the current rationales for risk stratification and the development of novel therapies. A final section then
explores supportive care, palliative care, late effects considerations and psychosocial issues as relate to children’s
cancer.


Table of Contents
Section One: Central Nervous System Tumours of Childhood.

1.1 Low and high-grade glioma.

1.2 Ependymoma.

1.3 Primitive neuroectodermal tumours.

1.4 Spinal cord tumours.

1.5 Miscellaneous tumours (Craniophyngioma, mixed neuronal tumours, rhabdoid tumour).

Section Two: Haematological Disorders.

2.1 Acute lymphoblastic leukaemia.

2.2 Acute myeloid leukaemia and myeloproliferative disorders.

2.3 Non-Hodgkins lymphoma.

2.4 Hodgkins disease.

2.5 Histiocytoses.

Section Three: Solid Tumours of Childhood.

3.1 Neuroblastoma.

3.2 Renal tumours.

3.3 Soft tissue tumours.

3.4 Bone tumours.

3.5 Hepatic tumours.

3.6 Germ cell tumours.

3.7 Retinoblastoma.

3.8 Rare tumours.

Section Four: Supportive Care, Long-Term Issues and Palliative Care.

4.1 Supportive care in relation to the physical consequences of cancer therapy.

4.2 Supportive care in relation to the psychological and social consequences of cancer therapy.

4.3 Late effects in relation to non-CNS tumours.

4.4 Late effects in relation to CNS tumours.

4.5 Palliative care