Heart Transplantation : Indication and Contraindicaitons Procedures and Complicaitons

Book Description:
Cardiac transplantation is a widely accepted therapy for the treatment of end-stage congestive heart failure. Most
candidates for cardiac transplantation have not been helped by conventional medical therapy and are excluded from other
surgical options because of the poor condition of the heart. About 45% of the candidates have ischemic cardiomyopathy;
however, this percentage is rising because of the increase in coronary artery disease in younger age groups. Of the
candidates, 54% have some form of dilated cardiomyopathy, which often has an unclear origin. The remaining 1% of
candidates fall into the category of other diseases, including congenital heart disease, that are not amenable to
surgical correction. Candidacy determination and evaluation are key components of the process, as is postoperative
follow-up care and immunosuppression management. This new book presents leading research from around the world.





Table of Contents:
Preface

1. Management of Tricuspid Regurgitation after Cardiac Transplantation
(Mitesh V. Badiwala, Vivek Rao, Division of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General
Hospital, University Health Network, and others) (pp. 1-9)

2. Virtual Histology Intravascular Ultrasound in Coronary Allograft Vasculopathy
(G. Sarno, W. Wijns, M. Vanderheyden, Aalst Cardiovascular Center, Belgium) (pp. 11-16)

3. Gene Therapy for Prevention of Acute and Chronic Cardiac Rejection
(Jun-ichi Suzuki, Mitsuaki Isobe, Ryuichi Morishita, and Ryozo Nagai, Department of Advanced Clinical Science and
Therapeutics, University of Tokyo, and others) (pp. 17-23)

4. Prevention of Heart Allograft Rejection by Immunotherapy with Ex Vivo-Expanded Foxp3+CD4+CD25+ Natural Regulatory T
Cells
(Guliang Xia, Zheng Zhang, Bryon D Johnson, Department of Surgery ?Organ Transplantation, Northwestern University
Feinberg School of Medicine, Chicago, Illinois, and others) (pp. 25-49)

5. Addressing the Shortage of Donor Cardiac Allografts ?Use of Marginal Grafts
(Silvana F Marasco, CJOB Cardiothoracic Surgery Unit, The Alfred Hospital, Melbourne, Australia, Andrew E Newcomb,
Cardiothoracic Sugery Unit, St. Vincent뭩 Hospital, Melbourne, Australia) (pp. 51-62)

6. Dendritic Cell Modulation for Therapeutic Immunoregulation in Heart Transplantation
(Marc-Estienne Roehrich, Manuel Pascual, Ludwig K. von Segesser, Pierre Vogt, Giuseppe Vassalli, Dept. of Cardiology,
Centre Hospitalier Universitaire Vaudois and Faculty of Biology and Medicine, University of Lausanne, Lausanne,
Switzerland, and others) (pp. 63-80)

7. Heart Transplantation: Indications and Contraindications, Procedures and Complications
(Katharina Kerschan-Schindl, Peter Pietschmann, Department of Physical Medicine & Rehabilitation, Medical University of
Vienna, and others) (pp. 81-89)

8. The Role of Statins in Heart Transplantation
(Nikolaos Bessias, Panagiotis Georgakis, Kosmas I. Paraskevas, Department of Vascular Surgery, Red Cross Hospital,
Athens, Greece, and others) (pp. 91-99)

9. Heart Transplantation from Non-Heart-Beating Donors; Future Transplantation^
(Masanori Hirota and Shunji Sano, Departments of Cardiovascular Surgery, Okayama University Graduate School of
Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan) (pp. 101-142)

10. An Innovative Treatment for Cardiac Failure: Autologous Stem Cell Tranplantation
(Gloria Invernici, Silvia Cristini,, Stefania Navone., Laura Canzi., Eugenio A. Parati,
The Neurobiology and Neuroregenerative Therapies Unit, Fondazione IRCCS Istituto Neurologico 밅arlo Besta? Milan,
Italy) (pp. 143-205)

11. Continuous, normothermic heart preservation in a modified Langendorff perfusion system?ultrastructural findings
and functional morphology in a pig model ^
(Heike Aupperle, Jens Garbade, Christian Krautz, Cris Ullmann, Sven Lehmann, J?g Kempfert, Michael A. Borger, Stefan
Dhein, Jan F. Gummert, Friedrich-Wilhelm Mohr, Institute of Veterinary-Pathology, Faculty of Veterinary Medicine,
University of Leipzig, Germany, and others) (pp. 207-229)

12. Non-Transplant Surgical Options for Cardiomyopathy
(Andrew E. Newcomb, St. Vincent's Hospital, Melbourne, Australia, Silvana F. Marasco, Alfred Hospital, Melbourne,
Australia and Nikunj Powar, Royal Melbourne Hospital, Melbourne, Australia* (pp. 231-272)

Index