Prognostic and Predictive Factors in Gynecologic Cancers

Table of Contents
Part I. Ovary
1. Clinical predictors of outcome in epithelial ovarian carcinoma
2. Influence of BRCA1 and BRCA2 on survival
3. Cell-cycle and apoptotic markers
4. p53 as a prognostic factor
5.Use of microarray and CGH technologies for predicting outcome
6. Angiogenesis and epithelial ovarian carcinoma
7. Cell-adhesion and matrix-associated proteins in ovarian carcinoma
8. Effect of immune factors on prognosis
9. Predictive factors in germ-cell and stromal tumors

Part II. Endometrium
10. Rethinking traditional surgical-pathologic criteria for early stage endometrial cancer: studies of patterns of
failure
11. Molecular prognostic and predictive factors in advanced endometrial cancer: implications for therapy
12. Inherited and acquired mismatch repair deficiency
13. Molecular profiling in endometrial cancer: Current research and implications for the future
14. Traditional and molecular predictors of behavior in uterine papillary serous carcinoma and clear cell carcinoma
Part III. Cervical
15. Clinical pathologic predictors in patients with cervical cancer
16. Predictors of radiation sensitivity and resistance
17. Molecular prognostic and predictive factors for cervix cancer
18. Virology in the prevention and management of cervical cancer
19. Molecular imaging for cervical cancer
20. Neuroendocrine cancer of cervix: prognostic and predictive factors
21. Predictive values of sentinel lymph nodes

Synopsis

Prognostic and Predictive Factors in Gynecologic Oncology takes a fresh look at a critical aspect of cancer treatment
planning. An international team of authors reviews the traditional prognostic and predictive factors such as tumor
grade, histologic subtype, and grade and then goes a step further to review the growing number of molecular discoveries
that have increasing clinical significance. The book is organized into comprehensive sections on ovarian, endometrial
and cervical cancer and includes up to date reviews, newly discovered molecular pathways, genetic markers, molecular
imaging techniques, and their relevance to clinical medicine.

Prognostic and Predictive Factors in Gynecologic Oncology is illustrated with over 100 figures and is essential reading
for oncologists, translational and basic scientists, as well as fellows, residents and students with a special interest
in gynecologic oncology.

Doody Review Services
Reviewer: David G. Mutch, MD (Washington University School of Medicine)
Description: This book describes the prognostic factors associated with gynecologic malignancies, incorporating the
current clinical features with newer molecular identifiers as well as those associate with newer imaging technologies.
This comprehensive and well written book is the first to focus on this issue and is a needed addition to the field of
gynecologic oncology.
Purpose: The purpose is to comprehensively compile prognostic data that has emerged relating to gynecologic cancers.
Clinical, molecular, and imaging data has accumulated as our technologic ability has increased. This compilation is
truly necessary if we are to continue to make improvements in the management of women with these cancers. The
objectives are met well in book written by world authorities in these diseases.
Audience: It is intended for all who are interested in women's cancers, including students, residents, fellows, basic
scientists, and clinicians. The authors are all authorities in this field.
Features: This well written and thorough book comprehensively collates the data available to date on gynecologic
cancers. It is a complete and thoughtful compilation of clinical, molecular, and imaging data on these cancers and is
structured in manner that is efficient and easy to understand.
Assessment: This is an excellent reference on this disease. It is a must read for those interested in gynecologic
malignancies.