Dementia 4/e

Summary:
This definitive work on dementia and related disorders has been fully updated and revised to reflect recent advances in
this fast moving field.
The incidence of dementia continues to rise as the population of the world ages, and the condition represents one of
the most significant challenges facing societies and health professionals in the next half-century. In this, the most
comprehensive single volume work available on the subject, the editors have met this challenge by assembling a team of
the world's leading experts on all aspects of the condition, from history, epidemiology and social aspects to the
latest neurobiological research and advanced therapeutic strategies.
The new edition includes:
?the latest neurobiological research made relevant to everyday practice
?a thorough review of all treatment strategies from drug and stem cell therapies through to psychosocial interventions
?a comprehensive review of carer support strategies, community care, long term care facilities, and behavioural
management techniques
?contributions from a team of leading international experts and recognised key opinion leaders.
The ebook uses VitalSource?Bookshelf ?an ebook reader which allows you to:
?download the ebook to your computer or access it anywhere with an internet browser
?search the full text and add your own notes and highlights
?link through from references to PubMed.
Dementia, Fourth Edition, is essential reading for all specialists in old age psychiatry, neurology and care of the
elderly. It will also prove invaluable for all clinicians working with patients affected by dementia, including
psychologists, occupational therapists, social workers and specialist nursing staff.




뷪he definitive work on the subject of dementia
뷪ruly international chapter authorship, representing the cream of the world's dementia researchers and clinicians
뷚ully revised and updated, reflecting the nature of this fast moving field
뷙ssential reading for old age psychiatrists and anyone whose work involves patients with dementia



Table of Contents:
Part I ?Dementia: General Aspects
Introduction
1. Dementia: historical overview
2. The lived experience of dementia
3. Prevalence and incidence of dementia
Diagnosis and assessment
4. Criteria for the diagnosis of dementia
5. Assessment of the patient with apparent dementia
6. Screening and assessment instruments for the detection and measurement of cognitive impairment
7. Neuropsychological assessment of dementia
8. Neuropsychiatric aspects of dementia
9. Measurement of neuropsychiatric symptoms, behavioural disturbance and quality of life
10. Cross-cultural issues in the assessment of cognitive impairment
Research findings from brain imaging and neurophysiology
11. Structural brain imaging
12. Functional brain imaging
13. Molecular brain imaging in dementia
14. The neurophysiology of dementia
The care and management of people with dementia
15. Family carers of people with dementia
16. One caregiver뭩 view
17. Dementia care in the community: challenges for primary health and social care
18. Managing co-morbidities and general hospital admissions for people with dementia
19. The role of nursing in the management of dementia
20. Social work and care/case management in dementia
21. Occupational therapy in dementia care
22. The role of the speech and language therapist in the assessment and management of
the patient with dementia
23. The role of the physiotherapist in the management of dementia
24. Therapeutic effects of music in persons with dementia
25. Psychological, behavioural and psychosocial interventions for neuropsychiatric symptoms in dementia
26. The case-specific approach to challenging behaviour in dementia
27. Pharmacological treatments for behavioural and psychological symptoms in Alzheimer's disease and other dementias
28. Psychological approaches for the practical management of cognitive impairment in dementia
29. Sexuality and dementia
30. Residential care for people with dementia
31. Design and dementia
32. Legal issues and dementia
33. Driving and dementia
34. Quality of life in dementia: conceptual and practical issues
35. Ethical issues and dementia
36. End of life decisions and dementia
37. Care and management of the patient with advanced dementia
38. Alzheimer Associations and societies
39. Health economic aspects of dementia
40. The global challenge of dementia: what can be done?
41. Development of a national strategy for dementia
42. The pharmaceutical industry and dementia
Part II Mild cognitive impairment
43. Mild cognitive impairment: A historical perspective
44. Clinical characterization of mild cognitive impairment
45. Managing the patient with mild cognitive impairment
Part III Alzheimer뭩 disease
Clinical aspects
46. What is Alzheimer뭩 disease?
47. Risk factors for Alzheimer뭩 disease
48. The natural history of Alzheimer뭩 disease
Neurobiology
49. The neuropathology of Alzheimer뭩 disease
50. The neurochemistry of Alzheimer뭩 disease
51. The role of A?amyloid in the pathogenesis of Alzheimer뭩 disease
52. The genetics of Alzheimer뭩 disease
53. Blood and cerebrospinal fluid biomarkers for Alzheimer뭩 disease
Therapeutic strategies to treat Alzheimer뭩 disease
54. Established treatments for Alzheimer's disease
55. Drug treatments in development for Alzheimer뭩 disease
56. Stem cell therapies for Alzheimer뭩 disease and other dementias
57. Vitamins and complementary therapies used to treat Alzheimer뭩 disease
58. Prevention of Alzheimer뭩 disease
59. Trial design for putative Alzheimer뭩 disease treatments
Part IV The overlap and interaction between Alzheimer뭩 disease and cerebrovascular disease
60. Vascular factors and Alzheimer뭩 disease
Part V Cerebrovascular disease and cognitive impairment
61. What is vascular cognitive impairment?
62. The neuropathology of vascular dementia
63. Therapeutic strategies for vascular dementia and vascular cognitive disorders
Part VI Dementia with Lewy bodies and Parkinson뭩 disease
64. Dementia with Lewy bodies: a clinical and historical overview
65. The pathology of dementia with Lewy bodies
66. The management of dementia with Lewy bodies
67. Cognitive impairment and dementia in Parkinson뭩 disease
Part VII Focal dementias and related issues
68. Frontotemporal dementia
69. Pick뭩 disease
70. The genetics and molecular pathology of frontotemporal lobar degeneration
71. Semantic dementia
72. Primary progressive aphasia and posterior cortical atrophy
73. The cerebellum and cognitive impairment
Part VIII Other dementias and neuropsychiatric disorders associated with cognitive impairments
74. Depression with cognitive impairment
75. Schizophrenia, cognitive impairment and dementia
76. Dementia and intellectual disability
77. Alcohol related dementia and Wernicke-Korsakoff syndrome
78. Huntingdon뭩 disease
79. Creutzfeldt-Jakob disease and other prion diseases
80. Uncommon forms of dementia




About the Author(s):
David Ames - BA, MD, FRCPSYCH, FRANZCP is Director of the National Ageing Research
Institute and Professor of Ageing and Health at the University of Melbourne, Australia
Alistair Burns - MPHIL, MD, FRCP, FRCPSYCH is Professor of Old Age Psychiatry at the University of Manchester,
Manchester Academic Health Science Centre, UK
John O묪rien BA, MA, DM, FRCPSYCH is Professor of Old Age Psychiatry at Institute for Ageing and Health, Newcastle
University, UK




Contributors:
Dag Aarsland MD PhD Psychiatric Clinic, Stavanger University Hospital, Stavanger, Norway George S Alexopoulos MD Weill
Cornell Medical College, White Plains, NY, USA Osvaldo P Almeida Western Australian Centre for Health and Ageing,
School of Psychiatry and Clinical Neurosciences and Centre for Medical Research, University of Western Australia;
Department of Psychiatry, Royal Perth Hospital, Perth, Australia June Andrews Iris Murdoch Building, University of
Stirling, Stirling, UK Sylvaine Artero PHD INSERM U888, Nervous System Pathologies: Epidemiological and Clinical
Research, La Colombi?e Hospital, Montpellier, France Clive Ballard Wolfson Centre for Age Related Diseases, Guy뭩
Campus, London, UK Sube Banerjee Professor of Mental Health and Ageing, The Institute of Psych



Readership:
Psychiatrists (9600 in the England) especially those specialising in in old age psychiatry (1300 of the 9600) and
general psychiatry (600 of the 9600). Geriatricians (3000 in England). Neurologists (1