Table of Contents
SECTION I INTRODUCTION TO IMMUNOLOGY 1
CHAPTER 1 GENERAL PROPERTIES OF IMMUNE RESPONSES 3
CHAPTER 2 CELLS AND TISSUES OF THE IMMUNE SYSTEM 14
SECTION II LYMPHOCYTE SPECIFICITY AND ACTIVATION 31
CHAPTER 3 ANTIBODIES AND ANTIGENS 33
CHAPTER 4 MATURATION OF B LYMPHOCYTES AND EXPRESSION OF IMMUNOGLOBULIN GENES 65
CHAPTER 5 THE MAJOR HISTOCOMPATIBILITY COMPLEX 96
CHAPTER 6 ANTIGEN PROCESSING AND PRESENTATION TO T LYMPHOCYTES 115
CHAPTER 7 MOLECULAR BASIS OF T CELL ANTIGEN RECOGNITION AND ACTIVATION 136
CHAPTER 8 T CELL MATURATION IN THE THYMUS 166
CHAPTER 9 B CELL ACTIVATION AND ANTIBODY PRODUCTION 187
CHAPTER 10 REGULATION OF IMMUNE RESPONSES 205
CHAPTER 11 FUNCTIONAL ANATOMY OF LOCAL AND SYSTEMIC IMMUNE RESPONSES 222
SECTION III EFFECTOR MECHANISMS OF IMMUNE RESPONSES 237
CHAPTER 12 CYTOKINES 239
CHAPTER 13 EFFECTOR MECHANISMS OF T CELL-MEDIATED IMMUNE REACTIONS 261
CHAPTER 14 EFFECTOR MECHANISMS OF IMMUNOGLOBULIN E-INITIATED IMMUNE REACTIONS 278
CHAPTER 15 THE COMPLEMENT SYSTEM 293
SECTION IV IMMUNITY IN DEFENSE AND DISEASE 317
CHAPTER 16 IMMUNITY TO MICROBES 319
CHAPTER 17 IMMUNE RESPONSES TO TISSUE TRANSPLANTS 337
CHAPTER 18 IMMUNITY TO TUMORS 356
CHAPTER 19 SELF-TOLERANCE AND AUTOIMMUNITY 376
CHAPTER 20 IMMUNE-MEDIATED TISSUE INJURY AND DISEASE 393
CHAPTER 21 CONGENITAL AND ACQUIRED IMMUNODEFICIENCIES 409
APPENDIX PRINCIPAL FEATURES OF KNOWN CD MOLECULES 431
INDEX 437