From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience 2/e

도서내용

An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic
building block, the neuron. This book provides the solid foundation of the morphological, biochemical, and biophysical
properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant
advances of the past five years. The new edition expands on the network aspects of cellular neurobiology by adding a
new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various
neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical
and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative
disease.


? Written and edited by leading experts in the field, the second edition completely and comprehensively updates all
chapters of this unique textbook

? Discusses emerging new understanding of non-classical molecules that affect neuronal signaling

? Full colour, professional graphics throughout

? Includes two new chapters: Information Processing in Neural Networks - describes the principles of operation of
neural networks and the key circuit motifs that are common to many networks in the nervous system. Molecular and
Cellular Mechanisms of Neurodegenerative Disease - introduces the progress made in the last 20 years in elucidating the
cellular and molecular mechanisms underlying brain disorders, including Amyotrophic Lateral Sclerosis (ALS), Parkinson
disease, and Alzheimer's disease.

? Twoexpansive, frequently updated support websites: one for students, with additional study materials, updated further
reading references, and quizzes; and one for instructors, providing all figures, solutions to quizzes and further
materials, PowerPoint lecture slides, and more.

목차

1 Cellular Components of Nervous Tissue
2 Subcellular Organization of the Nervous System: Organelles and Their Functions
3 Brain Energy Metabolism
4 Electrotonic Properties of Axons and Dendrites
5 Membrane Potential and Action Potential
6 Molecular Properties of Ion Channels
7 Dynamical Properties of Excitable Membranes
8 Release of Neurotransmitters
9 Pharmacology and Biochemistry of Synaptic Transmission: Classic Transmitters
10 Nonclassic Signaling in the Brain
11 Neurotransmitter Receptors
12 Intracellular Signaling
13 Regulation of Neuronal Gene Expression and Protein Synthesis
14 Mathematical Modeling and Analysis of Intracellular Signaling Pathways
15 Cell-Cell Communication: An Overview Emphasizing Gap Junctions
16 Postsynaptic Potentials and Synaptic Integration
17 Information Processing in Complex Dendrites
18 Learning and Memory: Basic Mechanisms
Index