Breast Cancer 2e

Foreword v
John Mendelsohn
Preface vii
Contributors xiii
Chapter 1
Multidisciplinary Care of Breast Cancer Patients:
Overview and Implementation 1
Eric A. Strom, Aman U. Buzdar, and Kelly K. Hunt
Chapter 2
Primary Prevention of Breast Cancer, Screening
for Early Detection of Breast Cancer, and Diagnostic
Evaluation of Clinical and Mammographic
Breast Abnormalities 27
Therese B. Bevers
Chapter 3
Genetic Predisposition to Breast Cancer
and Genetic Counseling and Testing 57
Kaylene J. Ready and Banu K. Arun
Chapter 4
Mammography, Magnetic Resonance Imaging
of the Breast, and Radionuclide Imaging of the Breast 83
Gary J. Whitman and Anne C. Kushwaha
Chapter 5
Breast Sonography 121
Bruno D. Fornage and Beth S. Edeiken-Monroe
Chapter 6
Image-Guided Biopsies of the Breast:
Technical Considerations, Diagnostic Challenges,
and Postbiopsy Clinical Management 163
Nour Sneige
Chapter 7
Surgical Options for Breast Cancer 197
Kelly K. Hunt and Funda Meric-Bernstam
Chapter 8
Breast Reconstruction 235
Pierre M. Chevray and Geoffrey L. Robb
Chapter 9
Radiation Therapy for Early and Advanced Breast Cancer 271
Welela Tereffe and Eric A. Strom
Chapter 10
Serum Tumor Markers and Circulating Tumor Cells 309
Francisco J. Esteva, Herbert A. Fritsche, Jr., James M. Reuben,
and Massimo Cristofanilli
Chapter 11
Histopathologic and Molecular Markers
of Prognosis and Response to Therapy 323
Lajos Pusztai and W. Fraser Symmans
Chapter 12
Chemotherapy for Breast Cancer 345
Marjorie C. Green and Gabriel N. Hortobagyi
Chapter 13
Stem Cell Transplantation for Metastatic
and High-Risk Nonmetastatic Breast Cancer:
A Novel Treatment Approach 387
Naoto T. Ueno, Michael Andreeff, and Richard E. Champlin
Chapter 14
Endocrine Therapy for Breast Cancer 411
Mary C. Pinder and Aman U. Buzdar
x Contents
Chapter 15
Gynecologic Problems in Patients with Breast Cancer 435
Elizabeth R. Keeler, Pedro T. Ramirez, and Ralph S. Freedman
Chapter 16
Special Clinical Situations in Patients with Breast Cancer 461
Karin M. E. Hahn and Richard L. Theriault
Chapter 17
Rehabilitation of Patients with Breast Cancer 485
Ying Guo and Anne N. Truong
Chapter 18
Menopausal Health after Breast Cancer 505
Gilbert G. Fareau and Rena Vassilopoulou-Sellin
Chapter 19
Sexuality and Breast Cancer Survivorship 525
Karin M. E. Hahn
Index 535

Essential clinical guide for oncologists, surgeons, and all physicians involved in breast cancer patient care
M.D. Anderson's current standard approach to breast cancer care
Detailed and key practice points provided for each chapter
New chapters on Molecular Prognostic and Predictive Markers, and Sexuality and Fertility Issues in Women with Breast
Cancer
Breast Cancer, Second Edition, is the seventh book in the M. D. Anderson Cancer Care Series. This book, like the others
in this series, highlights M. D. Anderson Cancer Center’s multidisciplinary approach and reviews the entire spectrum
of patient care, from prevention and screening through diagnosis and treatment through posttreatment follow-up and
survivorship issues.


This new edition of Breast Cancer has been extensively revised and updated. It covers newer approaches adopted since
the first edition of this book was published in 2001, such as new options for breast cancer prevention, the role of MRI
screening for women at high risk for breast cancer development, and integration of trastuzumab (Herceptin) into
treatment regimens for early breast cancer. A number of new tables and figures have been added as well.


In 19 comprehensive yet concise chapters, the experts at M. D. Anderson discuss primary prevention of breast cancer,
screening for early detection of breast cancer, genetic predisposition to breast cancer and genetic counseling and
testing, diagnostic imaging, pathology, surgical options, reconstructive surgery, radiation therapy, prognostic
markers, standard and high-dose chemotherapy, horm