Handbook of Botulinum Toxin Treatment (Hardcover)

Botulinum toxin A is a remarkably versatile treatment with a steadily expanding list of
indications, which include strabismus, hemifacial spasm, focal dystonias such as spasmodic
torticollis, dysphonia and writer's cramp, as well as adult and childhood spasticity. Recent
innovations include its use in some types of pain, in autonomic and gastrointestinal disorders, and
in cosmetic medicine, such as hyperhidrosis, hypersalivation, rectal fissure, achalasia and facial
wrinkles. Botulinum toxin is arguably the safest and most effective treatment in movement disorders
since the introduction of levodopa, and is an increasingly important option in many other fields.
The long-awaited second edition of the Handbook of Botulinum Toxin Treatment brings the reader up
to date with the many advances in background knowledge and in clinical practice in both the
established and the newer indications, including the use of a second serotype botulinum toxin B.
The book is an introduction and practical guide for doctors and paramedical staff who use botulinum
toxin or who may want to refer patients or care for patients being treated elsewhere. Initial
chapters provide historical and general information. The rest of the book concentrates on the
different conditions treated with botulinum toxin. Chapters follow a standard format with a
pragmatic approach based on the wide experience of the authors. Review from Doody's Review Service -
A five star rating! Description: This is a well-written and well-illustrated book that elegantly
details the utility of botulinum toxin in treating a variety of neurological conditions. Purpose:
The authors have created a superb, well-edited book that details the practical aspects of selecting
patients for botox injections as well as technique and possible adverse effects. Audience: Any
physician who plans to use botox in his or her practice -- whether for spasticity, dystonia, pain,
or cosmetic purposes will want to read and own this book. Features: This book is well written and
well edited. It consists of 18 contributions from authorities in the field. The first five
contributions delineate the discovery of botox and its mechanism of action. The next nine chapters
describe in detail the use of botox in a variety of movement disorders including blepharospasm,
tics, dystonia, spasticity, and tremor. Two chapters deal with treatment of autonomic disorders
with botox and the book concludes with three chapters on use of botox for pain, strabismus, and
cosmetic purposes. Assessment: This is a superb book that combines theory with practical
application. It is easy to read and filled with useful drawings. Any physician who wishes to use
botox in his or her practice will want to have this book. Score: Weighted Numerical Score: 99


List of Contributors
Foreword
Preface
Pt. 1 General
1 History and current applications of botulinum toxin - from poison to remedy by Markus Naumann
and Klaus Viktor Toyka and Peter Moore 3
2 How botulinum toxins work by Ornella Rossetto and Cesare Montecucco 9
3 General and clinical aspects of treatment with botulinum toxin by Peter Moore and Markus
Naumann 28
4 EMG for identification of dystonic, tremulous and spastic muscles and techniques for guidance of
injections by Jorg Wissel and Jorg Muller and Werner Poewe 76
Pt. 2 Movement disorders
5 Fundamentals of dystonia by Mitchell E. Brin 101
6 Blepharospasm, oromandibular dystonia, Meige's syndrome and hemifacial spasm by Mitchell E. Brin
and Fabio Danisi and Andrew Blitzer 119
7 The larynx and pharynx by Lucian Sulica and Jean Verheyden and Andrew Blitzer 142
8 Cervical and axial dystonia by Reiner Benecke and Peter Moore and Dirk Dressler and Markus
Naumann 158
9 Limb and occupational dystonia by Geoff Sheean 195
10 Spasticity in adults by Jean-Michel Gracies and Harald Hefter and David M. Simpson and Peter
Moor