-Introduction-
The most complete, trusted reference-text covering the full span of medical toxicology Market: Students, toxicologists,
and pharmacologists Focuses on the principles, concepts, and modes of thought that are the foundation of the discipline
New to this edition: updated throughout to reflect new understanding of cell death and drug metabolism, new content on
chemical terrorism, many new contributors
-Table of Contents-
Preface
Preface to the First Edition
UNIT 1: GENERAL PRINCIPLES OF TOXICOLOGY
1. History and Scope of Toxicology Michael A. Gallo
2. Principles of Toxicology David L. Eaton and Steven G. Gilbert
3. Mechanisms of Toxicity Zolt? Gregus
4. Risk Assessment Elaine M. Faustman and Gilbert S. Omenn
UNIT 2: DISPOSITION OF TOXICANTS
5. Absorption, Distribution, and Excretion of Toxicants Lois D. Lehman-McKeeman
6. Biotransformation of Zenobiotics Andrew Parkinson, and Brian Ogilvie
7. Toxicokinetics Danny D. Shen
UNIT 3: NON-ORGAN-DIRECTED TOXICITY
8. Chemical Carcinogens James E. Klaunig, and Lisa M. Kamendulis
9. Genetic Toxicology R. Julian Preston, and George R. Hoffmann
10. Developmental Toxicology John M. Rogers, and Robert J. Kavlock
UNIT 4: TARGET ORGAN TOXICITY
11. Toxic Responses of the Blood John C. Bloom, and John T. Brandt
12. Toxic Responses of the Immune System Norbert E. Kaminski, Barbara L. Faubert Kaplan, and Michael P. Holsapple
13. CHAPTER TO COME
14. Toxic Responses of the Kidney Rick G. Schnellmann
15. Toxic Responses of the Respiratory System Hanspeter R. Witschi, Kent E. Pinkerton, Laura S. Van Winkle, and Jerold
A. Last
16. Toxic Responses of the Nervous System Virginia C. Moser, Michael Aschner, Rudy J. Richardson, and Martin A.
Philbert
17. Toxic Responses of the Ocular and Visual System Donald A. Fox and William K. Boyes
18. Toxic Responses of the Heart and Vascular System Y. James Kang, DVM, PhD, FATS
19. Toxic Responses of the Skin Robert H. Rice, and Theodora M. Mauro
20. CHAPTER TO COME
21. Toxic Responses of the Endocrine System Charles C. Capen
UNIT 5: TOXIC AGENTS
22. Toxic Effects of Pesticides Luis G. Costa
23. Toxic Effects of Metals Jie Liu, Robert A. Goyer, and Michael P. Waalkes
24. Toxic Effects of Solvents and Vapors James V. Bruckner, Satheesh S. Anand, and D. Alan Warren
25. Health Effects of Radiation and Radioactive Materials Naomi H. Harley
26. Properties and Toxicities of Animal Venoms John B. Watkins, III
27. Toxic Effects of Plants Stata Norton
UNIT 6: ENVIRONMENTAL TOXICOLOGY
28. Air Pollution Daniel L. Costa
29. Ecotoxicology Richard T. Di Giulio, and Michael C. Newman
UNIT 7: APPLICATIONS OF TOXICOLOGY
30. Food Toxicology Frank N. Kotsonis, and George A. Burdock
31. CHAPTER TO COME
32. Clinical Toxicology Louis R. Cantilena Jr.
33. Occupational Toxicology Peter S. Thorne
Index
-Author Biography-
Curtis D. Klaasen, PhD, University Distinguished Professor and Chair, Kansas University School of Medicine; Kansas
City, Kansas.