Originally published in 2006, this is a comprehensive and definitive account of the human male gamete. The volume
summarizes many unique and revealing characteristics of the sperm cell. It provides a detailed overview of human sperm
production, maturation and function, and looks at how these processes affect and influence fertility, infertility and
ART. The volume thus provides a detailed review of the most important research and developments, augmented with
pertinent references. This book will appeal to all practitioners and scientists in reproductive medicine and in
particular to clinical scientists, graduate and post-graduate scientists, and laboratory personnel.
Table of Contents
1. Anatomical and compartmental analysis Peter Sutovsky and Gaurishankar Manandhar
2. Sperm chromatin stability and susceptibility to damage in relation to its structure Jeffrey A. Shaman and W. Steven
Ward
3. Genomic and proteomic approaches to defining sperm production and function Sarah Conner, Linda Lefi?re and
Christopher L. R. Barratt
4. The epididymis and sperm maturation Trevor Cooper and C. H. Yeung
5. Control of motility Claude Gagnon and Eve de Lamirande
6. Regulation of capacitation Pablo Visconti and B. M. Gadella
7. ROS's: friend or foe John Aitken and Liga Bennetts
8. Testing sperm manufacturing quality: the sperm-zona binding assay Sergio Oehninger and Daniel Franken
9. Genetics: a basic science perspective Peter Vogt
10. Sex chromosome abnormalities and male infertility: a clinical perspective Shai Shefi and Paul J. Turek
11. Epigenetic patterning in male germ cells: importance of DNA methylation to progeny outcome Jacquetta Trasler and
Sophie La Salle
12. The DAZ gene family and human germ cell development from embryonic stem cells Mark S. Fox, Renee A. Reijo Pera and
Amander T. Clark
Index.