- Contents -
Foreword
Preface
Ch. 1 Overview of the Immune System 3
Ch. 2 Experimental Systems 25
Ch. 3 Cells and Organs of the Immune System 47
Ch. 4 Antigens 87
Ch. 5 Immunoglobulins: Structure and Function 107
Ch. 6 Antigen-Antibody Interactions 143
Ch. 7 Organization and Expression of Immunoglobulin Genes 165
Ch. 8 B-Cell Maturation, Activation, and Differentiation 195
Ch. 9 Major Histocompatibility Complex 223
Ch. 10 Antigen Processing and Presentation 249
Ch. 11 T-Cell Receptor 263
Ch. 12 T-Cell Maturation, Activation, and Differentiation 285
Ch. 13 Cytokines 313
Ch. 14 The Complement System 335
Ch. 15 Leukocyte Migration and Inflammation 357
Ch. 16 Cell-Mediated and Humoral Effector Responses 379
Ch. 17 Hypersensitive Reactions 413
Ch. 18 Vaccines 443
Ch. 19 Immune Response to Infectious Diseases 459
Ch. 20 Autoimmunity 485
Ch. 21 Immunodeficiency Diseases 507
Ch. 22 The Immune System in AIDS 523
Ch. 23 Transplantation Immunology 555
Ch. 24 Cancer and the Immune System 573
Glossary 597
Answers to Study Questions 611
Credits 633
Index 641