The discovery of neurotransmission in a succinct and illustrative way
Neurochemical transmission accounts for the majority of information transfer
both in the central and peripheral nervous system. The initial findings centred
around the experimental work of the two Nobel Prize winners Sir Henry H. Dale
and Otto Loewi as well as Wilhelm Feldberg. Their historical findings opened
the door to further investigations and extended the list of neurotransmitters
to many others such as amino acids, peptides, purines and nitric oxide.
In the first part, the publication provides fascinating insights into the life
of the three scientists. Their personality and scientific approach are
presented through autobiographical sketches and personal memories by authors.
Various comments and details of the atmosphere in the laboratory complete the
picture of the conditions at the time.
The second part is dedicated to the history of the substances, such as
neurotransmitters, their antagonists and analogues. The stories of these
substances are presented to the reader in a succinct way, including many
anecdotes and unusual events on the way to their therapeutic application.