Contents
Dedication
Preface
Section Ⅰ: Immunology and Basic Science
1. Molecular Biology Techniques for the Investigation of Immune
Activation and Immunologic Dysfuction
2. Chemokines and Their Receptors
-Role and Functions of Chemokines
-Disease Involvement
-Assays
-Future Therapies
3. Mast cell- and Basophil-derived Mediators
-Morphology
-Mast Cell and Basophil Mediators
-Mast Cell ClassificationL Receptors and Activation
-Degranulation of Mast Cells and Basophils
-Therapies for Allergic Disease
4. The Eosinophil
-Clinical Conditions with Tissue and Blood Eosinophilia
-Morphology of Eosinophils and Eosinophil Products
-Immunobiology of Eosinophils
5. Aerobiology and Aeroallergens
-Sampling Devices
-Outdoor Aeroallergens
-Indoor Aeroallergens
6. Immunology Laboratory Techniques
-Allergy Skin Tests
-Nonradioactive Techniques That Use Immunologic Reagents
-The Gene Array Technique
-Techniques That Use High-performance Light Sources
-Techniques to Determine Phagocyte Dysfunction
7. Anaphylaxis
-Incidence and Epidemiology
-Anaphylaxis Versus Anaphylactoid Reactions
-Causes of Anaphylaxis
-Immunopathology
-Clinical Manifestations
-Prevention
-Therapy
Section Ⅱ: Allergy and Clinical Immunology
8. Urticaria and Angioedema
-Urticaria
-Angioedema
-Classification
-Mastocytosis
-Treatment
9. Atopic Dermatitis
10. Contact Dermatitis
11. Allergic Eye Disorders
-Atopic Disorders of The Eye
-Nonatopic Disorders of the Eye
-Opthalmologic Procedures in the Evaluation of Atopic Disorders of
the Eye
12. Rhinitis
-Mechanisms
-Etiology and Epidemiology
-Diagnosis
-Examination of the Nasal Cavity
-Physical Findings
-Therapy
13. Sinusitis
-Anatomy
-Etiology
-Imaging
-Chronic Sinusitis
-Indications for Surgery
-Complications of Sinusitis
-Pediatric Sinusitis
-Upper Respiratory and Head Neck Infections
14. Allergic Bronchopulmonary Aspergillosis
-Pulmonary Infiltrates with Eosinophilia Syndrome
-Diagnosis
-Clinical Stages
-Treatment
15. Hypersensitivity Pneumonitis
16. Pulmonary Function Testing and Bronchial Provocation
-Physiologic Basis of Pulmonary Function Testing
-Spirometry in the Clinical Setting
-Bronchial Provocation Challenge Testing
-Infant Pulmonary Function Tests
17. Allergen Immunotherapy
-Extracts, Vaccines, and Diagnostic Allergens
-Mite and Insect Allergens
-Mammalian Allergens
-Fire Ant and Hymenoptera Allergens
-Outdoor Allergens
-Fungal Allergens
-Immunologic Mechanisms
18. Latex Allergy
19. Asthma in Adults
-Epidemiology and Etiology
-Pathology and Pathogenesis
-Clinical Features and Diagnosis
-Management
20. Occupational Asthma
-Characteristics of Industrial Allergens and Inhalants
-Predisposing Factors
-Clinical and Pathogenic Features
-Diagnosis and Management
21. Food Allergy
-Clinical Manifestations of Food Hypersensitivity
-Diagnosing Adverse Food Reactions
-Management
-Prognosis
22. Insect Allergy
-Bites
-Systemic Allergic Reactions
23. Otitis Media
-Anatomy
-Classification
-Pathogenesis
-Evaluation
-Diagnosis
-Immune Evaluation
-Management
24. Aerosols and Inhaler Therapy
-Basic Aspects of Drug Delivery to the Lung
-Dry Powder Inhaler Delivery
-Nebulized Delivery
-Metered-Dose Inhaler Delivery
-Inhalation Techniques
25. Immunodeficiency Disorders
-Disorders of T- and B-cell Function
-Disorders of Granulocytes and Complement
-X-linked Agammaglobulinemia
-Common Varriable Immunodeficiency
-Combined Immunodeficiency and Severe Combined Immunodeficiency
-Chronic Mucocutaneous Candidasis
-Hyper-lgE Syndrome
-Chronic Granulomatous Disease
-Leukocyte Adhesion Deficiency
-Chediak-Higashi Syndrome
-Gene Defects
26. Allergic Drug Reations
-Typical Allergic Reactions to Drugs
-Antibiotic Allergy
-Drug Desensitization and Challenge Testing
-Radiocontrast Media Allergy
27. Anti-lgE Therapy for Allergic Asthma and Other Allergic Diseases
-Background
-Biology
-The Paradox of Increasing l