Color Atlas of Histopathology of the Cervix Uteri

The second edition of this atlas provides a detailed histopathological
diagnosis of cervical disease emphasizing carcinogenesis, and correlating
morphologic changes with clinical aspects. Instructions of how to obtain and
handle tissue samples are followed by a description of the normal histology, of
the action of steroid hormones on the cervix, and of the various forms of
regeneration and inflammation. The section on etiology and pathogenesis of HPV-
induced neoplasia has been enlarged to explain new insights into cellular and
nuclear deregulation at the molecular level. A chapter on immunohistochemistry
has been added which includes refined detection methods, e.g., with p16 for the
early differential diagnosis of premalignant lesions. The latest advances in
molecular biological research, with predictive subdivision of neoplasias,
facilitate the choice of the proper therapy. All chapters ?supported by over
20 new microphotographs ?have been revised to include advances in the
interpretation and management of cervical disease. The tumor nomenclature is
adapted to the new WHO classification; the ICD-O code has been added. The
reference list is updated with relevant publications.